 | Colin Farrell als Steven Murphy |
 | Nicole Kidman als Anna Murphy |
 | Barry Keoghan als Martin Lang |
 | Raffey Cassidy als Kim Murphy |
 | Sunny Suljic als Bob Murphy |
 | Bill Camp als Matthew Williams |
 | Alicia Silverstone als Martin's Mother |
 | Herb Caillouet als Ed Thompson (Hospital Director) |
| Barry G. Bernson als Dr. Larry Banks |
 | Denise Dal Vera als Mary Williams |
| Drew Logan als Principal |
| Ming Wang als Doctor (Abdominal) |
| Michael Trester als Elderly Man |
 | Anita Farmer Bergman als Nurse (uncredited) |
 | Lea Hutton Beasmore als Conference Guest (uncredited) |
| Dylan Keith Adams als Doctor at Conference and Event Dinner (uncredited) |
 | Charles Poole als Patient / Fisherman (uncredited) |
| John W. Harden als Conference Guest / Paramedic (uncredited) |
 | Bryant Bentley als Paramedic (uncredited) |
| Aaron Pullins IV als Medical Conference Attendee (uncredited) |
 | Joanne Popolin als Medical Conference Attendee (uncredited) |
 | Carly Tamborski als Doctor at Conference (uncredited) |
| David Pittinger als Student's Dad (uncredited) |
| Michael Lee Bailey als Conference Guest (uncredited) |
| John Newsom als Doctor at Banquet (uncredited) |
| Robert Gerding als Visiting Consultant (uncredited) |
 | William C. Ingram als Janitor (uncredited) |
| Beverly Kristy als Doctor (uncredited) |
 | Derek Polen als Conference Guest (uncredited) |
 | John E. Brownlee als Coastal Walker (uncredited) |
| Yorgos Lanthimos | Director |
| Ed Guiney | Producer |
| Thimios Bakatakis | Director of Photography |
| Yorgos Mavropsaridis | Editor |
| Jade Healy | Production Design |
| Adam Willis | Set Decoration |
| Nancy Steiner | Costume Design |
| Yorgos Lanthimos | Producer |
| D. Lynn Meyers | Casting |
| Daniel Baker | Art Direction |
| Holly Fisk | Set Decoration |
| A. Patrick Storey | Property Master |
| Belle Francisco | Script Supervisor |
| Pamela Ford | Craft Service |
| Johnnie Burn | Music Editor |
| Sarah Giles | Music Supervisor |
| Nick Payne | Music Supervisor |
| Claudia Sarbu | Assistant Costume Designer |
| Jaclyn Laravie | Key Costumer |
| Joseph Arena | Steadicam Operator |
| Matt Fleischmann | Steadicam Operator |
| Chris Salamone | Dolly Grip |
| Russ Faust | Gaffer |
| Scott Lipez | Best Boy Electric |
| Atsushi Nishijima | Still Photographer |
| Vadim Draempaehl | 3D Artist |
| Kenneth Coyne | Visual Effects Producer |
| Ed Bruce | Visual Effects Supervisor |
| Nicholas Murphy | Visual Effects Supervisor |
| Kelvin R. Trahan | Hair Department Head |
| Crystal Lewis | Hairstylist |
| Tanya Tieman | Hairstylist |
| Tina Roesler Kerwin | Makeup Department Head |
| Anna Richardson | Makeup Artist |
| Andrea Vieth | Makeup Artist |
| Jonathan Collard | Digital Intermediate |
| Neil Harrison | Digital Intermediate |
| Patrick Malone | Digital Intermediate |
| Charlotte Barnes | Digital Intermediate |
| Maria Chamberlain | Digital Intermediate |
| Georgina Cranmer | Digital Intermediate |
| Mark Neale | First Assistant Editor |
| Johnnie Burn | Sound Designer |
| Max Behrens | Sound Effects Editor |
| Steve Browell | Sound Effects Editor |
| Simon Carroll | Sound Effects Editor |
| Ed Downham | Sound Effects Editor |
| Ashley Smith | Sound Mixer |
| Efthymis Filippou | Writer |
| Yorgos Lanthimos | Writer |
| Andrew Lowe | Executive Producer |
| Daniel Battsek | Executive Producer |
| David Kosse | Executive Producer |
| Sam Lavender | Executive Producer |
| Nicki Hattingh | Executive Producer |
| Amit Pandya | Executive Producer |
| Anne Sheehan | Executive Producer |
| Peter Watson | Executive Producer |
| Marie-Gabrielle Stewart | Executive Producer |
| Will Greenfield | Co-Producer |
| Paula Heffernan | Co-Producer |
| Atilla Salih Yücer | Co-Producer |
| Francine Maisler | Casting Director |
| Kamen Velkovsky | Associate Producer |
| Emily Kacere | Unit Production Manager |
| Atilla Salih Yücer | First Assistant Director |
| Peter Wolf | Second Assistant Director |
| Verity Wislocki | Post Production Supervisor |
| Niall Brady | Dialogue Editor |
| Jean McGrath | Foley Mixer |
| Caoimhe Doyle | Foley Artist |
| Brendan Rehill | Foley Editor |
| Taylor Morgan | Production Coordinator |
| Keith Potter | Executive Producer |
| Vasilis Marmatakis | Graphic Designer |
| Yorgos Mavropsaridis | Music Editor |
| Ariane Labed | Thanks |
| Emer O'Shea | Production Coordinator |
| Sofiya Gubaydulina | Sound |
| Jodi Byrne | Makeup Artist |
| David Greathouse | Special Effects Makeup Artist |
| Vasilis Marmatakis | Title Designer |
