 | Ray Milland als Don Birnam |
 | Jane Wyman als Helen St. James |
 | Phillip Terry als Wick Birnam |
 | Howard Da Silva als Nat the Bartender |
 | Doris Dowling als Gloria |
 | Frank Faylen als 'Bim' Nolan |
 | Mary Young als Mrs. Deveridge |
 | Anita Sharp-Bolster als Mrs. Foley |
 | Lilian Fontaine als Mrs. Charles St. James |
 | Frank Orth als Opera Cloak Room Attendant |
 | Lewis L. Russell als Charles St. James |
 | Andy Andrews als Alcoholic (uncredited) |
 | Walter Baldwin als Man from Albany (uncredited) |
 | Harry Barris als Pianist at Harry & Joe's (uncredited) |
| Jess Lee Brooks als (uncredited) |
 | Jack Rube Clifford als Guard (uncredited) |
 | David Clyde als Dave (uncredited) |
| James Conaty als Man in Nightclub Washroom (uncredited) |
| Willa Pearl Curtis als Mrs. Wertheim's Assistant (uncredited) |
 | John Deauville als Cloakroom Attendant (uncredited) |
| Helen Dickson als Mrs. Frink (uncredited) |
 | Franklyn Farnum als Concert Attendee (uncredited) |
 | Byron Foulger als Shopkeeper (uncredited) |
 | Jayne Hazard als M. (uncredited) |
 | Ted Hecht als Man with Bandaged Ear (uncredited) |
 | Ernest Hilliard als Headwaiter (uncredited) |
 | Earle Hyman als Smoking Man (uncredited) |
| Jerry James als Male Nurse (uncredited) |
| Stan Johnson als Nurse (uncredited) |
 | Jack W. Johnston als Nightclub Guest (uncredited) |
 | Karl 'Karchy' Kosiczky als Baby (uncredited) |
| Eddie Laughton als Mr. Brophy (uncredited) |
| Perc Launders als Doorman (uncredited) |
| Bertram Marburgh als Jewish Man (uncredited) |
| William Meader als Hardware Man (uncredited) |
 | James Millican als Nurse (uncredited) |
 | Frank Mills als Drunk in Alcoholic Ward (uncredited) |
| Pat Moriarity als Irishman (uncredited) |
 | William Newell als Liquor Store Proprietor (uncredited) |
| William O'Leary als Irishman (uncredited) |
| Peter Potter als Shaky and Sweaty Man (uncredited) |
 | Stanley Price als Fruit Clerk (uncredited) |
 | Craig Reynolds als George (uncredited) |
| Lester Sharpe als Jewish Man (uncredited) |
 | Lee Shumway als Guard (uncredited) |
 | Douglas Spencer als Hospital Patient Seeing Imaginary Beetles (uncredited) |
| Al Stewart als Mattress Man (uncredited) |
 | Amzie Strickland als Woman in Bar (uncredited) |
 | Harry Tenbrook als Drunk in Alcoholic Ward (uncredited) |
 | Fred 'Snowflake' Toones als Washroom Attendant at Harry & Joe's (uncredited) |
 | Emmett Vogan als Doctor (uncredited) |
| Max Wagner als Mike (uncredited) |
| Milton Wallace als Pawnbroker with Helen's Coat (uncredited) |
| Gisela Werbisek als Mrs. Wertheim (uncredited) |
 | Crane Whitley als Waiter at Harry & Joe's Bar (uncredited) |
 | Ernest Whitman als Black Man Talking to Himself (uncredited) |
 | Harry Wilson als Drunk (uncredited) |
| Isabel Withers als Woman Before Pawn Shop (uncredited) |
 | Audrey Young als Cloak Room Attendant (uncredited) |
| Charles R. Jackson | Novel |
| Charles Brackett | Screenplay |
| Billy Wilder | Screenplay |
| Charles Brackett | Producer |
| Miklós Rózsa | Original Music Composer |
| John F. Seitz | Director of Photography |
| Edith Head | Costume Design |
| Doane Harrison | Editorial Manager |
| Hans Dreier | Art Direction |
| A. Earl Hedrick | Art Direction |
| Gordon Jennings | Visual Effects |
| Farciot Edouart | Visual Effects |
| Wally Westmore | Makeup Artist |
| Bertram C. Granger | Set Decoration |
| Billy Wilder | Director |
| Richard Blaydon | Production Manager |
| Frank Parmenter | Production Manager |
| Charles C. Coleman | Assistant Director |
| Gene Lauritzen | Construction Coordinator |
| Sidney Cutner | Orchestrator |
| Leo Shuken | Orchestrator |
| Doane Harrison | Editor |
| Jack Colconda | Props |
| Harlow Stengel | Assistant Camera |
| Fred True | Grip |
| Stanley Cooley | Sound Recordist |
| Joel Moss | Sound Recordist |
