 | Abbi Jacobson als Katie Mitchell / Dog Cop (voice) |
 | Danny McBride als Rick Mitchell (voice) |
 | Maya Rudolph als Linda Mitchell (voice) |
 | Mike Rianda als Aaron Mitchell / Furbies / Talking Dog / Wifi Enthusiast (voice) |
 | Eric André als Mark Bowman (voice) |
 | Olivia Colman als PAL (voice) |
 | Fred Armisen als Deborahbot 5000 (voice) |
 | Beck Bennett als Eric / PAL Max Robots (voice) |
 | Chrissy Teigen als Hailey Posey (voice) |
 | John Legend als Jim Posey (voice) |
 | Charlyne Yi als Abbey Posey (voice) |
 | Blake Griffin als PAL Max Prime (voice) |
 | Conan O'Brien als Glaxxon 5000 (voice) |
 | Doug the Pug als Monchi (voice) |
 | Melissa Sturm als Sarge / Melissa (Woman In Pod) (voice) |
| Doug Nicholas als Hamburger Boy / Smart-Racket 5000-S Series (voice) |
 | Madeleine McGraw als Young Katie (voice) |
| Ellen Wightman als Baby Katie (voice) |
 | Sasheer Zamata als Jade (voice) |
 | Elle Mills als Hanna (voice) |
 | Alex Hirsch als Dirk (voice) |
 | Jay Pharoah als Noah (voice) |
 | Natalie Canizares als Catherine (Food Blogger) (voice) |
 | Jeff Rowe als Man Who Loves Fun (voice) |
 | Zeno Robinson als Sean (Unboxer) (voice) |
 | Grey DeLisle als Stagehand (voice) |
| Will Allegra als Water Fountain Man (voice) |
 | Alison Rich als Jill (Woman In Pod) (voice) |
 | Natalia del Riego als Additional Voices (voice) |
| Libby Thomas Dickey als Additional Voices (voice) |
| Kerry Gutierrez als Additional Voices (voice) |
| Todd Hansen als Additional Voices (voice) |
 | Lex Lang als Additional Voices (voice) |
 | Greg Levitan als Additional Voices (voice) |
 | Griffin McElroy als Additional Voices (voice) |
 | Caitlin McKenna als Additional Voices (voice) |
 | Andrew Morgado als Additional Voices (voice) |
| Illya Owens als Additional Voices (voice) |
 | Juan Pacheco als Additional Voices (voice) |
 | Ashley Peldon als Additional Voices (voice) |
 | Jim Pirri als Additional Voices (voice) |
 | Michelle Ruff als Additional Voices (voice) |
 | Justin Shenkarow als Additional Voices (voice) |
 | Shane Sweet als Additional Voices (voice) |
| Brittanny Tuerpe als Additional Voices (voice) |
| Alana Webster als Additional Voices (voice) |
 | Jason Linere-White als Additional Voices (voice) |
 | Lisa Wilhoit als Additional Voices (voice) |
 | Adam Wylie als Additional Voices (voice) |
| Christopher Miller | Producer |
| Phil Lord | Producer |
| Kurt Albrecht | Producer |
| Jeff Rowe | Writer |
| Mike Rianda | Writer |
| Mike Rianda | Director |
| Alan Tyler | Additional Music |
| Will Allegra | Executive Producer |
| Louis Koo | Executive Producer |
| Daniel Chuba | Co-Producer |
| Carey Smith | Co-Producer |
| John Pospisil | Sound Designer |
| Michael Semanick | Sound Re-Recording Mixer |
| Mark Mothersbaugh | Original Music Composer |
| Michael Lasker | Visual Effects Supervisor |
| Greg Levitan | Editor |
| Lindsey Olivares | Character Designer |
| Lindsey Olivares | Production Design |
| Rich Turner | Head of Layout |
| Toby Wilson | Art Direction |
| Kier Lehman | Music Supervisor |
| Peter Szilagyi | Script Coordinator |
| Jeff Rowe | Co-Director |
| Brittany N. Grooms | Casting |
| Tamara Hunter | Casting |
| Mary Hidalgo | Additional Casting |
| Ian Whittaker | Set Decoration |
| Nobuteru Sasagawa | Character Designer |
| Alice Lemma | Character Designer |
| Fabien Mense | Character Designer |
| Christopher Wright | Character Designer |
| James A. Castillo | Character Designer |
| Todd Hansen | Additional Editor |
| Doug Nicholas | Additional Editor |
| Tony Ferdidand | Associate Editor |
| R. Collin Wightman | Associate Editor |
| T.J. Young | Associate Editor |
| Bret Allen | First Assistant Editor |
| Arin Mathern | Assistant Editor |
| Katie Greathouse | Music Editor |
| Jun'ya Otake | Animation |
| Kellan Jett | Visual Development |
| Nick Bradshaw | Visual Development |
| John Butiu | Visual Development |
| Peter Chan | Visual Development |
| Arthur Fong | Visual Development |
| Matthew Divito | Visual Development |
| Rocky Curby | Visual Development |
| Jayse Hansen | Visual Development |
| Faris Hermiz | Visual Development |
| Michael Isaak | Visual Development |
| Yashar Kassai | Visual Development |
| Alex Konstad | Visual Development |
| Garrett Lee | Visual Development |
| Ryan Lang | Visual Development |
| Tiffany Lam | Visual Development |
| Sylvain Marc | Visual Development |
| Lizzie Nichols | Visual Development |
| Lily Nishita | Visual Development |
| Brittany Shively | Visual Development |
| Michael V. Schroeder | Visual Development |
| Jake Panian | Visual Development |
| Ian Worrel | Visual Development |
| Juan Couto | Animation |
| Joe Darko | Lead Animator |
| Federico Abib | Lead Animator |
| Emmanuel Gatera | Lead Animator |
| Nicholas Georgeou | Lead Animator |
| Earl Brawley | Lead Animator |
| Lindsey Butterworth Langston | Lead Animator |
| Martin Sen | Lead Animator |
| David Wesch | Lead Animator |
| Bobby Taylor | Lead Animator |
| Adam Sarophim | Lead Animator |
| Chelsea Gordon-Ratzlaff | Lead Animator |
| Robin George | Lead Animator |
| Guillermo Martinez | Head of Story |
| Alan Hawkins | Head of Animation |
| Jocelyn Cofer | Supervising Animator |
| Chad Ellis | Supervising Animator |
| Tim Kallok | Supervising Animator |
| Nick Kondo | Supervising Animator |
| Rohini Kumar | Supervising Animator |
| Toby Pedersen | Supervising Animator |
| Jose Luis Llado Porquer | Supervising Animator |
| JP Welsh | Animation |
| Thanawat Khantrum | Animation |
| Mario Richard | Animation |
| Kelsey Wagner | Supervising Animator |
| Matt Shepherd | Supervising Animator |
| Tim Rudder | Supervising Animator |
| Dylan Reid | Supervising Animator |
| Kevin Herron | Animation |
| Tristan Jeanbourquin | Animation |
| Yuko Ikeda | Animation |
| Chaeyeon Lee | Animation |
| Sejin Lee | Animation |
| Jenny Sining Li | Animation |
| Robert Lehman | Animation |
| Dave Mah | Animation |
| Minseok Lee | Animation |
| Julius Kwan | Animation |
| Aleksandar Kolev | Animation |
| Seongbae Jeong | Animation |
| Ina Marczinczik | Animation |
| Hanung Lee | Animation |
| JD Walsh | Animation |
| Mikey Wong | Animation |
| Mitchell Yeager | Animation |
| Vaskinta Atika | Animation |
| Hanna Cho | Story Artist |
| Myke Bakich | Story Artist |
| Koko Wing Hei Chou | Story Artist |
| Justin Hunt | Story Artist |
| Brandon Jeffords | Story Artist |
| Rachel Kral | Story Artist |
| Quinne Larsen | Story Artist |
| Ben Mansfield | Story Artist |
| Andrew James Ross | Story Artist |
| Vitaliy Strokous | Story Artist |
| Caitlin VanArsdale | Story Artist |
| Ray Xu | Story Artist |
| Kasey Fagerquist | Story Artist |
| Arthur D. Noda | Editor |
| Jeff Rowe | Director |
| Matt Braly | Storyboard Artist |
| Dana Terrace | Storyboard Artist |
