 | Oscar Isaac als Mikael Boghosian |
 | Charlotte Le Bon als Ana Khesarian |
 | Christian Bale als Chris Myers |
 | Daniel Giménez Cacho als Reverend Dikran Antreassian |
 | Tom Hollander als Garin |
 | Shohreh Aghdashloo als Marta Boghosian |
 | Rade Šerbedžija als Stephan |
 | Marwan Kenzari als Emre Ogan |
 | Angela Sarafyan als Maral |
 | Numan Acar als Mustafa |
 | Igal Naor als Mesrob |
 | Milene Mayer als Yeva |
 | Tamer Hassan als Faruk Pasha |
 | Alicia Borrachero als Lena |
 | Abel Folk als Harut |
 | Jean Reno als Admiral Fournet |
 | James Cromwell als Henry Morgenthau Sr. |
 | Kevork Malikyan als Vartan Boghosian |
| Lucía Zorrilla als Tamar |
 | Roman Mitichyan als Van |
 | Armin Amiri als Captain Ali |
 | Stewart Scudamore als Ismet Ogan |
 | Andrew Tarbet als Pastor Merril |
| Aharon Ipalé als Dr. Nazim |
| Shnorhk Sargsyan als Komitas |
 | Aaron Neil als Talaat Pasha |
| James Chanos als General Zyniker |
 | Anthony Rotsa als Ahmet |
 | Michael Stahl-David als Brad |
 | Àlex Maruny als Sharp Shooter 2 |
 | Diogo Andrade als Turkish Student (Uncredited) |
 | Sofia Black-D'Elia als Older Yeva |
 | Luis Callejo als Turkish Intelligence Officer |
 | Julián Villagrán als Armenian Soldier |
 | Alain Hernández als Turkish Telegraph Officer |
 | Vic Tablian als Cattle Car Man |
| Terry George | Writer |
| Terry George | Director |
| Robin Swicord | Writer |
| Steven Rosenblum | Editor |
| Gabriel Liste | Art Direction |
| Dídac Bono | Supervising Art Director |
| Óscar Sempere | Art Direction |
| José Luis Saldaña | Set Decoration |
| Mark Albela | Line Producer |
| Benjamín Fernández | Production Design |
| Alejandro Fernández | Art Direction |
| Ian Bedford | Associate Producer |
| Pilar Revuelta | Set Decoration |
| Ralph Winter | Producer |
| Eric Esrailian | Producer |
| Edward McGurn | Co-Producer |
| Mike Medavoy | Producer |
| Carla Garapedian | Associate Producer |
| Denise O'Dell | Producer |
| Paula Maestro | Set Decoration |
| Pierre-Yves Gayraud | Costume Design |
| William Horberg | Producer |
| Avy Kaufman | Casting |
| Edward Said | Casting |
| Camilla-Valentine Isola | Casting |
| Gabriel Yared | Original Music Composer |
| Javier Aguirresarobe | Director of Photography |
| Martin Ware | Casting Associate |
| Militza Vélez | Seamstress |
| Maralyn Causley | Script Supervisor |
| Oriol Nogues | Assistant Costume Designer |
| Randall Balsmeyer | Title Designer |
| James Seymour Brett | Music Director |
| Leeba Zakharov | Casting Associate |
| Tim McKelvey | Costume Supervisor |
| Cristina Sopeña | Wardrobe Supervisor |
| Anna Izquierdo | Set Costumer |
| José Vico | Assistant Costume Designer |
| Isabel Finkler | Costume Supervisor |
| Rocío Redondo | Set Costumer |
| Patricia Amor | Casting Associate |
| Eudald Magri | Assistant Costume Designer |
| Susan Boyajian | ADR Voice Casting |
| John Hubbard | Casting |
| Jon Goracy | Casting Associate |
| Bettina Seifert | Costume Supervisor |
| Béatrice Kruger | Casting |
| Oriol Busquets | Camera Operator |
| John Grillo | Second Unit Director of Photography |
| Manuel Nevosad | Rigging Gaffer |
| Renee Burke | Script Supervisor |
| David Domínguez | Camera Operator |
| Dave Hamilton-Green | Steadicam Operator |
| Patrick DeVine | Digital Intermediate |
| Agustín Serna G. Lavín | First Assistant Editor |
| Tina Earnshaw | Makeup Department Head |
| Douglas Kirkland | Still Photographer |
| Iván Sequeira | Dolly Grip |
| Abel Zoe Rodriguez | Lighting Technician |
| Joanna McCarthy | Key Makeup Artist |
| Louise McCarthy | Makeup Department Head |
| Arcadio Sequeira | Rigging Gaffer |
| José Luis Rodríguez | Gaffer |
| John Preca Trapani | Underwater Camera |
| Adenike Wright | Hairstylist |
| Michael Ludwig | Dolly Grip |
| William M. Weberg | Key Grip |
| Joaquín 'Kino' Sánchez | Gaffer |
| Ailbhe Lemass | Key Makeup Artist |
| Matteo Silvi | Key Makeup Artist |
| José Haro | Still Photographer |
| José Lebrón | Boom Operator |
| Paul Hsu | Supervising Sound Editor |
| Tom Fleischman | Sound Re-Recording Mixer |
| Patricia Brolsma | Boom Operator |
| Frank Kern | Foley Editor |
| Deborah Wallach | Supervising ADR Editor |
| Paul Hsu | Sound Re-Recording Mixer |
| Dámaso Hernández | Boom Operator |
| Philip Stockton | Supervising Sound Editor |
| Marko Costanzo | Foley |
| Bill Orrico | Sound Editor |
| Bruce Souza | Animation |
| Malte Sarnes | VFX Supervisor |
| Thibaud Galbois | Visual Effects Coordinator |
| Jacques Levesque | Visual Effects Supervisor |
| Lluna Juvé | Location Scout |
| Ana Rubio | Visual Effects Coordinator |
| David Temprano | Assistant Art Director |
| Juan Aguirre | Property Master |
| Eli Gavete | Transportation Coordinator |
| Sara Bourque | Visual Effects Coordinator |
| Mani Martínez | Property Master |
| Navdeep Singh | Animation |
| Jesse Hood | Visual Effects Coordinator |
| Virginie Lavallée | Visual Effects Coordinator |
| Adam O'Brien-Locke | Visual Effects Producer |
| Bryan Hirota | Visual Effects Supervisor |
| Charlie Galea | Picture Car Coordinator |
| Helen Martí Donoghue | Visual Effects Coordinator |
| Katherine Soares | Visual Effects Coordinator |
| Alan Ciantar | Location Manager |
| Dave Shaw | Marine Coordinator |
| Christian Mallia | Transportation Coordinator |
| Mariel Sanchez | Animation |
| Christopher Ahrens | CG Supervisor |
| Rémi Ducharme | Visual Effects Coordinator |
| Sébastien Bergeron | Visual Effects Supervisor |
| Ramón Alonso | Transportation Captain |
| Pau Costa | Special Effects Supervisor |
| Sara Bold | Visual Effects Coordinator |
| Amelie Poitras | Visual Effects Producer |
| Mark Russell | Visual Effects Supervisor |
| Andrés Leal Chele | Transportation Coordinator |
| Nadine Frève | Visual Effects Editor |
| Juanma Nogales | Visual Effects Supervisor |
| Monette Dubin | Visual Effects Producer |
| Jorge Leonardo | Location Scout |
| Frédérique Schmidt | Visual Effects Editor |
| Céline Zapater | Visual Effects Editor |
| Fabrice Vienne | CG Supervisor |
| Rocio Sainz Herrero | Assistant Art Director |
| Óscar Romero | Property Master |
| Kenneth Cassar | Special Effects Supervisor |
| Kristen Drewski | Visual Effects Coordinator |
| Jordi Casares | Stunt Coordinator |
