 | Amber Tamblyn als Tibby Rollins |
 | America Ferrera als Carmen Lowell |
 | Blake Lively als Bridget Vreeland |
 | Alexis Bledel als Lena Kaligaris |
 | Rachel Nichols als Julia Beckwith |
 | Tom Wisdom als Ian |
 | Rachel Ticotin als Christina Lowell |
 | Leonardo Nam als Brian McBrian |
 | Michael Rady als Kostas Dounas |
 | Shohreh Aghdashloo als Professor Nasrin Mehani |
 | Blythe Danner als Greta |
 | Jesse Williams als Leo |
 | Lucy Hale als Effie Kaligaris |
 | Maria Konstadarou als Yia Yia |
 | Ernie Lively als Franz Vreeland |
 | Stevie Ray Dallimore als Nigel O'Bannon |
 | Alison Folland als Stage Manager Margaret |
 | Zacharoula Klimatsaki als Melia |
| Paul Coughlan als David Breckman |
| Rebekah Aramini als Ariadne Kaligaris |
 | Cory Nichols als Nicky Rollins |
| Carly Rose Sonenclar als Katherine Rollins |
 | Adrienne Bailon-Houghton als Cute Video Couple Girl |
 | Kiely Williams als Yaffa Waitress |
 | Kyle MacLachlan als Bill Kerr (uncredited) |
 | Harry L. Seddon als Tibby's Dad (uncredited) |
 | Victor Slezak als Doctor |
 | Marceline Hugot als Nurse |
| Sanaa Hamri | Director |
| Elizabeth Chandler | Screenplay |
| Ann Brashares | Novel |
| Kira Davis | Producer |
| Sergio Kotsovoulos | Production Design |
| Andrew Max Cahn | Art Direction |
| Melissa Kent | Editor |
| Rachel Portman | Original Music Composer |
| Denise Di Novi | Producer |
| George DeTitta Jr. | Set Decoration |
| Yolanda T. Cochran | Co-Producer |
| Gaylyn Fraiche | Co-Producer |
| Gae S. Buckley | Production Design |
| Broderick Johnson | Producer |
| Andrew A. Kosove | Executive Producer |
| Debra Martin Chase | Producer |
| Bob Levy | Executive Producer |
| Alison Greenspan | Executive Producer |
| Steven P. Wegner | Co-Producer |
| Jim Denault | Director of Photography |
| Leslie Morgenstein | Executive Producer |
| Dona Granata | Costume Design |
| Christine A. Sacani | Executive Producer |
| Richard Patrick | First Assistant Director |
| Colin MacLellan | Second Assistant Director |
| Christos Dervenis | Third Assistant Director |
| Kimberly Shannon Murphy | Stunt Double |
| Anthony Vincent | Stunts |
| Julia Michels | Music Supervisor |
| Laura Rosenthal | Casting |
| Ali Farrell | Casting |
| Margot Lulick | Unit Production Manager |
| Amy Lynn | Second Assistant Director |
| G. A. Aguilar | Stunt Coordinator |
| Mariana Hellmund | Script Supervisor |
| John Kasarda | Assistant Art Director |
| Tom Warren | Assistant Art Director |
| Nora Kasarda | Art Department Coordinator |
| Gay Howard | Art Department Coordinator |
| Susan Kaufman | Assistant Set Decoration |
| Regina Graves | Assistant Set Decoration |
| Gerald DeTitta | Leadman |
| David H. Allen | Property Master |
| Ruth DiPasquale | Assistant Property Master |
| Jim McConkey | Steadicam Operator |
| David Knox | "B" Camera Operator |
| Aurelia Winborn | First Assistant "A" Camera |
| Doug Foote | Second Assistant "A" Camera |
| Pierson Silver | First Assistant "B" Camera |
| Amy Silverman | Second Assistant "B" Camera |
| Scott H. Ramsey | Gaffer |
| Ben Noble | Best Boy Electric |
| Rocco Palmieri | Rigging Gaffer |
| Kurt Rimmel | Key Grip |
| Joe Doughan | Best Boy Grip |
| Johnny Erbes-Chan | Dolly Grip |
| Robert Kummert | Rigging Grip |
| Edmund Tomaselli | Set Medic |
| Mathew Price | Sound Mixer |
| Linda Murphy | Boom Operator |
| Kate Edwards | Costume Supervisor |
| Emily Gunshor | Assistant Costume Designer |
| Jessica Glenn | Costume Coordinator |
| Mindy Hall | Makeup Department Head |
| Autumn Moultrie | Makeup Artist |
| Mary Anne Spano | Makeup Artist |
| Michael Kriston | Hair Department Head |
| Kathy Lineberger | Hairstylist |
| Christine Cantrell | Hairstylist |
| Paul Kramer | Location Manager |
| Daniel Coss | Assistant Location Manager |
| Kate Killoran Dowd | Location Coordinator |
| Dan Cooley | Location Scout |
| Heather Mullen | First Assistant Editor |
| Trudy Yee | Assistant Editor |
| Ken Nelson | Construction Coordinator |
| Sierra Drucker | Music Coordinator |
| Angela Conde | Extras Casting |
| Melissa Braun | Extras Casting |
| Paula Jack | Dialogue Coach |
| Colin MacLellan | Second Second Assistant Director |
| Cameron Frankley | Sound Designer |
| Jon Michaels | Sound Editor |
| David V. Butler | Supervising Dialogue Editor |
| Petra Bach | ADR Supervisor |
| Ai-Ling Lee | Sound Effects Editor |
| Jason W. Jennings | Sound Effects Editor |
| Thomas J. O'Connell | ADR Mixer |
| Rick Canelli | ADR Recordist |
| John Roesch | Foley Artist |
| Alyson Dee Moore | Foley Artist |
| Gregory H. Watkins | Sound Re-Recording Mixer |
| Tim LeBlanc | Sound Re-Recording Mixer |
| David Carbonara | Music Editor |
| Jeff Atmajian | Orchestrator |
| Lee Wimer | Color Timer |
| David Gere | Stunts |
