 | Tom Hanks als Viktor Navorski |
 | Catherine Zeta-Jones als Amelia Warren |
 | Stanley Tucci als Frank Dixon |
 | Chi McBride als Mulroy |
 | Diego Luna als Enrique Cruz |
 | Barry Shabaka Henley als Thurman |
 | Kumar Pallana als Gupta Rajan |
 | Zoe Saldaña als Dolores Torres |
 | Eddie Jones als Salchak |
 | Jude Ciccolella als Karl Iverson |
 | Corey Reynolds als Waylin |
 | Guillermo Díaz als Bobby Alima |
 | Rini Bell als Nadia |
 | Stephen Mendel als Steward First Class |
 | Valeriy Nikolaev als Milodragovich |
 | Michael Nouri als Max |
 | Ana Maria Quintana als Government Inspector |
 | Bob Morrisey als Government Inspector |
 | Sasha Spielberg als Lucy |
 | Susan Slome als Woman with Cart |
 | Mik Scriba als Transportation Liaison |
 | Jim Ishida als Yoshinoya Manager |
 | Carlease Burke als Brookstone Manager |
 | Stephon Fuller als Swatch Manager |
 | Dan Finnerty als Discovery Store Manager |
 | Anastasia Basil als La Perla Employee Julie |
 | Lydia Blanco Garza als Burger King Employee |
 | John Eddins als CBP Officer |
 | Kenneth Choi als CBP Officer |
 | Cas Anvar als CBP Officer |
 | Conrad Pla als CBP Officer |
 | Danette MacKay als CBP Officer |
 | Ian Finlay als CBP Officer |
 | Janique Kearns als CBP Officer |
 | Eddie Santiago als Man on Phone |
 | Kevin Ryder als Businessman |
 | Dusan Dukic als Young Drug Trafficker |
 | Mark Ivanir als Cab Driver Goran |
 | Matt Holland als Ramada Inn Clerk |
 | Benny Golson als Himself |
| Buster Williams als Bass |
| Mike Ledonne als Piano |
| Carl Allen als Drums |
 | Scott Adsit als Cab Driver |
 | Robert Covarrubias als Janitor |
 | Terry Haig als CBP Inspector |
| Jeff Michael als Anchor |
| Dilva Henry als Anchor |
 | Michelle Arthur als Field Reporter |
| Thinh Truong Nguyen als Passenger |
| Sandrine Kwan als Passenger |
 | Carl Alacchi als Passenger |
 | Tanya van Blokland als Passenger |
 | Evelyne de la Chenelière als Passenger |
| Laurie Meghan Phelps als Homeland Security Officer |
 | Ryan Stockstad als Brookstone Employee (uncredited) |
| Jeff Nathanson | Screenplay |
| Steven Spielberg | Producer |
| Jason Hoffs | Executive Producer |
| Patricia Whitcher | Executive Producer |
| Sacha Gervasi | Screenplay |
| Mary Zophres | Costume Design |
| Isabelle Guay | Art Direction |
| Anne Kuljian | Set Decoration |
| Richard C. Franklin | Supervising Sound Editor |
| Michael Kahn | Editor |
| Debra Zane | Casting |
| Christine Wada | Costume Design |
| Steven Spielberg | Director |
| Walter F. Parkes | Producer |
| Janusz Kamiński | Director of Photography |
| Laurie MacDonald | Producer |
| Brad Ricker | Art Direction |
| Andrew Niccol | Executive Producer |
| John Williams | Original Music Composer |
| Alex McDowell | Production Design |
| Lucie Robitaille | Casting |
| Zoltan Elek | Makeup Artist |
| Helene Lamarre | Art Department Coordinator |
| Merrick Morton | Still Photographer |
| Ana Maria Quintana | Script Supervisor |
| Johanne Gravel | Makeup Artist |
| Michael Lantieri | Special Effects Supervisor |
| Julia Nessling-Douglas | Digital Intermediate |
| Cosmas Paul Bolger Jr. | Visual Effects Producer |
| Kevin Blauvelt | Rigging Gaffer |
| Gary Wright | Sound Effects Editor |
| Michael Trent | First Assistant Editor |
| Cindy J. Williams | Makeup Artist |
| Peter Myles | Music Editor |
| John DeLuca | Choreographer |
| Doug Jackson | Sound Effects Editor |
| Patrick Crane | First Assistant Editor |
| Daniel C. Striepeke | Makeup Artist |
| Mitch Dubin | Camera Operator |
| Clay Liversidge | Rigging Gaffer |
| Dawn Fintor | Foley |
| Kim Santantonio | Hair Department Head |
| Andrea Carter | Art Department Coordinator |
| Jessica Lichtner | Script Supervisor |
| Steven Meizler | First Assistant Camera |
| Katalin Elek | Makeup Artist |
| Charles Gibson | Visual Effects Supervisor |
| Cha Blevins | Costume Supervisor |
| Charles L. Campbell | Supervising Sound Editor |
| Thomas Real | Key Hair Stylist |
| Johanne Paiement | Key Hair Stylist |
| Greg Funk | Makeup Artist |
| Alicia Stevenson | Foley |
| Karyn Huston | Hairstylist |
| Robert Stromberg | Visual Effects Supervisor |
| Paul LeBlanc | Hairstylist |
| George Billinger III | Steadicam Operator |
| Tannis Vallely | Casting Associate |
| Brian Lukas | Rigging Gaffer |
| Odin Benitez | Sound Effects Editor |
| Bruce MacCallum | Camera Operator |
| Edouard F. Henriques | Makeup Department Head |
| Mildred Iatrou | Dialogue Editor |
| Vanessa Lapato | ADR Editor |
| Vidar Neuhof | Property Master |
| Ron Judkins | Production Sound Mixer |
| R.J. Kizer | ADR Supervisor |
| Doug Harlocker | Property Master |
| Doug Coleman | Stunt Coordinator |
| Chris Palermo | Utility Stunts |
| Andrew Niccol | Story |
| Sacha Gervasi | Story |
| Sergio Mimica-Gezzan | Co-Producer |
| Christopher Burian-Mohr | Art Direction |
| Frank L. Bare II | Utility Stunts |
| Sandy Berumen | Stunt Double |
| Joey Box | Utility Stunts |
| Kurt D. Lott | Utility Stunts |
| Marc Désourdy | Stunt Coordinator |
| Allen Robinson | Utility Stunts |
| Kerry Rossall | Utility Stunts |
| Brian Machleit | Stunt Double |
| Cheryl Lawson | Stunt Double |
| Marcello Bezina | Stunts |
| Patrick Sabongui | Stunts |
| Stéphane Byl | Stunts |
| Javier Segura | Stunts |
| Stéphane Byl | Assistant Director |
| David H. Venghaus Jr. | Second Assistant Director |
| Sergio Mimica-Gezzan | First Assistant Director |
| Anna Behlmer | Sound Re-Recording Mixer |
| Michael Lantieri | Special Effects |
| David Ebner | Visual Effects Supervisor |
| Nicolas Lepage | Art Direction |
