 | Denzel Washington als Macbeth |
 | Frances McDormand als Lady Macbeth |
 | Alex Hassell als Ross |
 | Bertie Carvel als Banquo |
 | Brendan Gleeson als Duncan |
 | Corey Hawkins als Macduff |
 | Harry Melling als Malcolm |
 | Miles Anderson als Lennox |
 | Kathryn Hunter als Witches / Old Man |
 | Matt Helm als Donalbain |
 | Moses Ingram als Lady Macduff |
 | Scott Subiono als Murderer |
 | Brian Thompson als Murderer |
 | Lucas Barker als Fleance |
 | Stephen Root als Porter |
 | Robert Gilbert als Angus |
 | Ethan Hutchison als Macduff's Son |
 | James Udom als Seyton |
 | Richard Short als Siward |
 | Sean Patrick Thomas als Monteith |
 | Ralph Ineson als Captain |
 | Jefferson Mays als Doctor |
 | Olivia Washington als Children’s Nurse |
 | Susan James Berger als Lady in Waiting |
 | Wayne T. Carr als Lady Macduff’s Murderer |
 | Jacob McCarthy als Wheyface |
 | Nancy Daly als Lady Macbeth's Nurse |
 | Kayden Alexander Koshelev als Apparition Boy |
 | Ledger Fuller als Apparition Boy |
| T.K. Weaver als Apparition Boy |
| Edward Headington als Thane of Cawdor (uncredited) |
| Tim Oakes als Duncan's Protector (uncredited) |
 | Peter Janov als Soldier (uncredited) |
 | Max Baker als Doctor (uncredited) |
| Madison Randolph als Macduff's Daughter (uncredited) |
| Phil DiGennaro als Demitrius (uncredited) |
| Joel Coen | Director |
| Carter Burwell | Music |
| Stefan Dechant | Production Design |
| Mary Zophres | Costume Design |
| Bruno Delbonnel | Director of Photography |
| Frances McDormand | Producer |
| Robert Graf | Producer |
| Joel Coen | Producer |
| Catherine Farrell | Co-Producer |
| Jason T. Clark | Art Direction |
| Nancy Haigh | Set Decoration |
| Jean Ann Black | Makeup Department Head |
| Cydney Cornell | Hair Designer |
| Cydney Cornell | Hair Department Head |
| Josh Foster | Makeup Artist |
| Iman Newborn | Hairstylist |
| Cynthia P. Romo | Hairstylist |
| Terrie Velazquez Owen | Key Hair Stylist |
| Karen Ruth Getchell | Production Manager |
| Robert Graf | Unit Production Manager |
| Ellen Chenoweth | Casting |
| Katterli Frauenfelder | First Assistant Director |
| Jeff Hubbard | Second Assistant Director |
| Aaron Hasson | ADR Mixer |
| Gavin Hecker | Foley Mixer |
| Randall L. Johnson | Boom Operator |
| Peter F. Kurland | Sound Mixer |
| Igor Nikolic | Foley Supervisor |
| Jay Peck | Foley Artist |
| Nick Roberts | ADR Mixer |
| Michael Huber | Visual Effects Supervisor |
| Alex Lemke | Visual Effects Supervisor |
| Joel Coen | Screenplay |
| William Shakespeare | Theatre Play |
| Lucian Johnston | Editor |
| Caitlin Disney | Costumer |
| Tim Croshaw | Set Designer |
| Colin Sieburgh | Set Designer |
| Michael Thurman | Set Dresser |
| Trinh Vu | Set Designer |
| Jane Wuu | Set Designer |
| Michael LaCorte | Art Department Coordinator |
| Rich Pernice | VFX Artist |
| Mark Avery | Set Costumer |
| Michelle Kurpaska | Costume Supervisor |
| Paul Urmson | Sound Re-Recording Mixer |
| Skip Lievsay | Supervising Sound Editor |
| Skip Lievsay | Sound Re-Recording Mixer |
| Michael Bauman | Gaffer |
| Joel Coen | Editor |
| Hanna Woltz | Assistant Set Decoration |
| Sophie Kay | Costume Assistant |
| Kelli Barksdale | Stunts |
| Denise Acosta | Art Department Assistant |
