 | Andra Day als Billie Holiday |
 | Trevante Rhodes als Jimmy Fletcher |
 | Garrett Hedlund als Harry Anslinger |
 | Leslie Jordan als Reginald Lord Devine |
 | Miss Lawrence als Miss Freddy |
 | Adriane Lenox als Mrs. Fletcher |
 | Natasha Lyonne als Tallulah Bankhead |
 | Rob Morgan als Louis McKay |
 | Da'Vine Joy Randolph als Roslyn |
 | Evan Ross als Agent Williams |
 | Tyler James Williams als Lester 'Prez' Young |
 | Tone Bell als John Levy |
 | Blake DeLong als Agent Carter |
 | Dana Gourrier als Sadie |
 | Melvin Gregg als Joe Guy |
 | Erik LaRay Harvey als James Monroe |
 | Ray Shell als Carl The Drummer |
 | Dusan Dukic als Joe Glaser |
 | Koumba Ball als Lucille |
 | Kate MacLellan als Working Class Woman |
 | Kwasi Songui als Working Class Man |
 | Letitia Brookes als Velva |
 | Warren 'Slim' Williams als Bobby Tucker |
 | Orville Thompson als Auditioning Sax Player |
 | Jeff Corbett als Congressman JP Thomas |
 | Damian Joseph Quinn als Roy Cohn |
 | Robert Alan Beuth als Congressman J. Rankin |
 | Randy Davison als Senator J. McCarthy |
 | Kevin Hanchard als Louis Armstrong |
| Jono Townsend als Guitar Player |
| Morgan Moore als Bass Player |
| Arlen John Bonnar als Priest |
| Furly Mac als Elevator Attendant |
| Andrew Zadel als Agent McDermott |
 | Tristan D. Lalla als Mr. Jordon Green |
 | Alex Bisping als Bailiff #1 |
 | Don Anderson als Judge Ganey |
| Amanda Strawn als Gloria |
| Charleine Charles als Shirley |
 | Sylvia Stewart als Stink-Eye Inmate |
| Daphné Archer als Jail Dishwasher |
| Anita Lee als Fighting Woman |
| Tony Chao als Fighting Man |
| Linda Sauvé als Receptionist |
 | Alain Goulem als Ed Fishman |
| Ramona Clyke als Miss Mona |
| Laurent Beaudin als Ed Fishman's Assistant |
 | Alika Autran als Martha Anslinger |
 | Kim Feeney als Lady In Audience |
| Diana Carmen Ratycz als Carnegie Fan |
 | Richard Jutras als Uptown Restaurant Maître d' |
 | Jonathan Higgins als Defense Lawyer Erlich |
| Marc Essertaize als Bailiff #2 |
 | Nealla Gordon als Courthouse Reporter |
 | Len Blavatnik als Club Owner |
 | Christopher Ricardo Price als Drug Dealer |
| Taryn Brown als Billie (10 years old) |
| Zuri Hawkins als Little Girl in Brothel |
 | Elizabeth Eveillard als Prostitute 1923 |
 | Clauter Alexandre als Husband |
 | Penande Estime als Hanging Woman |
| Elikya Tupula als Young Daughter |
| Nefertari Zanyah Brewster-Griffith als Older Daughter |
 | Joe Cobden als George Jessel |
 | Ronda Louis-Jeune als Jimmy's Girlfriend |
 | Maxime Paradis als Producer |
 | Sarah Levesque als Nurse |
 | Donald Fullilove als Additional Voices (voice) |
| Lee Daniels | Director |
| Suzan-Lori Parks | Screenplay |
| Joe Roth | Producer |
| Jeff Kirschenbaum | Producer |
| H.H. Cooper | First Assistant Director |
| Jeremy Allen | Executive Producer |
| Mark Bomback | Executive Producer |
| Marie Cisco | Co-Producer |
| Cassian Elwes | Executive Producer |
| Jordan Fudge | Producer |
| Wellington Love | Co-Producer |
| Hilary Shor | Executive Producer |
| Tucker Tooley | Producer |
| Pamela Oas Williams | Producer |
| Jay Rabinowitz | Editor |
| Leah Daniels Butler | Casting |
| Billy Hopkins | Casting |
| Ashley Ingram | Casting |
| Daniel T. Dorrance | Production Design |
| Carolyne de Bellefeuille | Art Direction |
| Léa-Valérie Létourneau | Assistant Art Director |
| Andrew Dunn | Director of Photography |
| Kris Bowers | Original Music Composer |
| Johann Hari | Book |
| Lee Daniels | Producer |
| Johann Hari | Executive Producer |
| Dennis Stratton | Executive Producer |
| Patty Long | Executive Producer |
| Paolo Nieddu | Costume Designer |
| Jahil Fisher | Co-Producer |
| H.H. Cooper | Co-Producer |
| Simone Sheffield | Co-Executive Producer |
| Salaam Remi | Executive Music Producer |
| Amanda Ghost | Executive Music Producer |
| Lynn Fainchtein | Music Supervisor |
| Kevin Scott | Casting |
| Hélène Ross | Unit Production Manager |
| George Parra | Unit Production Manager |
| Patty Long | Unit Production Manager |
| Fanny Hudon | Second Assistant Director |
| Jeremy Green | Associate Producer |
| Jake Meyers | Associate Producer |
| Tom Westfall | Associate Producer |
| Rodney Alexandre | Stunt Coordinator |
| Tyler Hall | Stunt Coordinator |
| Michael Scherer | Stunt Coordinator |
| Chelsea Jackson | Stunts |
| Rodney Alexandre | Stunts |
| Jason Conyers | Stunts |
| Otis Hopson | Stunts |
| Mario Allard | Musician |
| Giovany Arteaga | Musician |
| Hubert Brizard | Musician |
| Drey Demo | Musician |
| Nicola Di Lauro | Musician |
| Claude Gelineau | Musician |
| Ken Joseph | Musician |
| Jean Laplante | Musician |
| Jean-Marc Martel | Musician |
| Daniel Plamondon | Musician |
| François D'Anjou Pomerleau | Musician |
| Peter Purich | Musician |
| Olivier Allard | Musician |
| Carl Beaudoin | Musician |
| Nicolas Cousineau | Musician |
| Maxime Despax | Musician |
| Schadrac Émilica | Musician |
| Sébastien Grenier | Musician |
| Laszlo Koos | Musician |
| Patrice Luneau | Musician |
| Nathan Mignien | Musician |
| Kieran Poile | Musician |
| Jacques Proulx | Musician |
| Jeremy Sandfelder | Musician |
| Charles-Antoine Solis | Musician |
| Félix Larivière-Charron | Supervising Art Director |
| Vincent Aird | Art Direction |
| Luc-Eric Duhamel | Assistant Art Director |
| Guy Pigeon | Set Designer |
| Simon Théberge | Set Designer |
| Isabelle Côté | Graphic Designer |
| Anne-Marie Giroux | Graphic Designer |
| Cecile Braemer | Art Department Coordinator |
| Nutan Khanna | Clearances Coordinator |
| Andrew Dunn | "A" Camera Operator |
| Dany Racine | First Assistant "A" Camera |
| Soupharak Keoborakoth | Second Assistant "A" Camera |
| Yoann Malnati | "B" Camera Operator |
| Yoann Malnati | Steadicam Operator |
| Nicolas Marion | First Assistant "B" Camera |
| Eric Aubin | Second Assistant "B" Camera |
| Isabelle Lauzon | Camera Loader |
| Christian Caperaa | Camera Loader |
| Sylvaine Dufaux | "C" Camera Operator |
| Michel Bernier | First Assistant "C" Camera |
| Jean-Francois Tousignant | Second Assistant "C" Camera |
| Salome Dufaux-Mathieu | Camera Trainee |
| Charles Castonguay | Video Assist Operator |
| Jean-Francois Landry | Libra Head Technician |
| Elizabeth Tremblay | Script Supervisor |
| Claude La Haye | Sound Recordist |
| Francis Péloquin | Boom Operator |
| Thomas Sedillot | Sound Assistant |
| Eames Gagnon | Chief Lighting Technician |
| Daniel Goyens | Assistant Chief Lighting Technician |
| Constant Lavallée | Lighting Technician |
| Frederic Nivoix | Lighting Technician |
| Monica Caballero Moreno | Lighting Technician |
| Sébastien Lauzon | Lighting Technician |
| Marc Hénaut | Lighting Technician |
| Christopher Cadorette | Lighting Technician |
| Frederic Moreau | Lighting Technician |
| Ryan Faulconbridge | Lighting Technician |
| Alain Apollon | Lighting Technician |
| Éric Morin | Generator Operator |
| Jeremy Martin | Lighting Coordinator |
| Christine Chu | Lighting Coordinator |
| Daniel Dinel | Key Grip |
| Rémi Giroux | Dolly Grip |
| Joost Clerinx | Dolly Grip |
| Martin Landry | Grip |
| Jonathan Barbeau | Grip |
| Johanzen Aldana Espinosa | Grip |
| Jean-Phillipe Gauthier | Grip |
| Simon Hébert | Grip |
| Steve Montplaisir | Grip |
| Christophe Desjardins | Grip |
| Christian Chabot | Grip |
| Melanie St-Pierre | Grip |
| Eric Belanger | Grip |
| Thierry Lacombe | Grip |
| Claude Gervais | Grip |
| Alexandra Elkin | Grip |
| Martin Boiteau | Grip |
| Daniel Robidoux | Key Rigging Grip |
| Dominic Prevost | Rigging Grip |
| Michael Robidoux | Rigging Grip |
| Emile Gonin Robidoux | Rigging Grip |
| Stephane St-Pierre | Rigging Grip |
| Carmelo Staguitta | Rigging Grip |
| Alexandre Dumas | Rigging Grip |
| Cedric Arcand | Rigging Grip |
| Gabriel Boudrau | Rigging Grip |
| Frederic Calve | Rigging Grip |
| Guillaume Vidal | Rigging Grip |
| Frederic Bilodeau | Rigging Grip |
| Jean-François Dubé | Rigging Grip |
| Adam Robidoux | Rigging Grip |
| Philippe Lacrois | Rigging Grip |
| Kathy Ann Thomas | Production Coordinator |
| Eva Quintero | Assistant Production Coordinator |
| Odette Lavigne | Travel Coordinator |
| Patricia Ferris | Production Secretary |
| Stéphanie-Alexandra Joseph | Receptionist |
| Myriam Santos | Actor's Assistant |
| Andre Thomas | Actor's Assistant |
| Adrienne Williams | Actor's Assistant |
| Ben Poppleton | Actor's Assistant |
| Thom Jones | Dialect Coach |
| Harris Ellison | Third Assistant Director |
| Shanna Roberts Salée | Third Assistant Director |
| Ami Diakité | Assistant Director Trainee |
| Brigitte St-Onge | Unit Manager |
| Benoit Thériault | Assistant Unit Manager |
| Stephane Desharnais | Assistant Unit Manager |
| Jonathan Meunier | Set Production Assistant |
| Valérie Caron | Back-up Set Production Assistant |
| Martin Roy | Truck Production Assistant |
| Christian Rollin | Back-up Truck Production Assistant |
| Ben Clune | Producer's Assistant |
| Danny Williams | Producer's Assistant |
| Adam Davis | Producer's Assistant |
| Ian Malcolm | Producer's Assistant |
| Tom Di Blasio | Production Accountant |
| Flora Eleftheriou | First Assistant Accountant |
| François Choinière | Payroll Accountant |
| Benoît Mathieu | Location Manager |
| Lynne Dauphinee | Location Scout |
| Andrea Kenyon | Local Casting |
| Randi Wells | Local Casting |
| Julie Breton | Extras Casting |
| Melissa Nepton | Extras Casting Assistant |
| Simone Leclerc | Property Master |
| Olivier Proulx | Assistant Property Master |
| Andrew Law | Props |
| Eulalie Gagne | Props |
| Vidar Neuhof | On Set Key Props |
| Vincent Brabant | On Set Props |
| Sarah-Rose Buchanan | On Set Props |
| Pascale Deschênes | Decorator |
| Geneviève Boivin | Decorator |
| Jacques Rajotte | Decorator |
| Josée Arsenault | Decorator |
| Yves Allard | Assistant Decorator |
| Marzia Pellissier | Assistant Decorator |
| Léonie Lavoie | Assistant Decorator |
| Ariane Leroux-Ringuette | Assistant Decorator |
| Michèle Laroche | Leadman |
| Colin Lavigne | Set Dresser |
| Vincent Morin | Set Dresser |
| Eduardo Santibanez | Set Dresser |
| Julie Baumann | Set Dresser |
| Alexis St-Denis | Set Dresser |
| Martin Leblanc | Set Dresser |
| Joakim Rivest-Girard | Set Dresser |
| Alain Clouâtre | Set Dresser |
| Frédérick Marcil | Set Dresser |
| Jason Sheppard | Set Dresser |
| Elissa Arsenault Soupras | Set Dresser |
| Julyan Chamorro | Set Dresser |
| Julien Bocciarelli | Set Dresser |
| Jimmy Brassard | Set Dresser |
| Stephan McKenzie | On Set Dresser |
| Guillaume Murray | Special Effects Supervisor |
| Andre Fortin | Special Effects Technician |
| Etienne Trepanier | Special Effects Technician |
| Marc Godding | Special Effects Technician |
| Stacey Godding | Special Effects Technician |
| Nedra Gribaa | Assistant Costume Designer |
| Pat Welch | Costume Supervisor |
| Katrina Marie Lukaitis | Costume Coordinator |
| Gigi Duval | Key Dresser |
| Susana Vera | Tailor |
| Cristina Carvalho | Wardrobe Specialized Technician |
| Deborah Adams | Seamstress |
| Priscillia Collin | Seamstress |
| Lynda Goode | Seamstress |
| Sylvie Théberge | Seamstress |
| Viriya Say | Seamstress |
| Laurie-Anne St-Pierre Savard | Seamstress |
| Sigesmund Moser | Tailor |
| Laini Thompson | Makeup Department Head |
| Catherine Lavoie | Makeup Artist |
| Camiel McLean | Assistant Makeup Artist |
| Lizane La Salle | Assistant Makeup Artist |
| Sophie Lebeau | Assistant Makeup Artist |
| Sandra Ruel | Assistant Makeup Artist |
| Genevieve Bonneau | Assistant Makeup Artist |
| Chanelle Ouellette | Assistant Makeup Artist |
| Sherry Hu | Assistant Makeup Artist |
| Kathy Tse | Special Effects Key Makeup Artist |
| Caroline Aquin | Special Effects Makeup Artist |
| Vague Vartanian | Special Effects Makeup Artist |
| Charles Gregory Ross | Hair Department Head |
| T.A. Henderson | Hairdresser |
| Liliane Saad | Hairdresser |
| Gladys Simard | Assistant Hairdresser |
| Sarah Tremblay | Assistant Hairdresser |
| Nathalie Garon | Assistant Hairdresser |
| Mario Saint-Louis | Assistant Hairdresser |
| Martin Lapointe | Assistant Hairdresser |
| Marie-Eve Menard | Assistant Hairdresser |
| Pascale Royer | Assistant Hairdresser |
| Janie Otis | Assistant Hairdresser |
| Nathalie Dion | Assistant Hairdresser |
| Jerry Asiedu Pipim | Assistant Hairdresser |
| Manon Joly | Assistant Hairdresser |
| Francoise Lortie | Assistant Hairdresser |
| André Duval | Assistant Hairdresser |
| Rocco Stallone | Assistant Hairdresser |
| Charles Gregory Ross | Wig Designer |
| Bob Kretschmer | Wigmaker |
| Puelo Deir | Unit Publicist |
| Takashi Seida | Still Photographer |
| Mirsad Osmanbasic | Set Medic |
| Thamara Antoine | Set Medic |
| Josée Juteau | Animal Wrangler |
| Rejean Brochu | Construction Coordinator |
| Ann Brochu | Construction Manager |
| Rémi Beaudoin | Head Carpenter |
| Richard Cardin | Head Carpenter |
| Pablo Figueroa | Head Carpenter |
| Marc-André Proulx | Head Carpenter |
| Jean-Philippe Silvestro | Head Carpenter |
| Reno Hebert | Greensman |
| Myriam Tallard | Greensman |
| Olya Zarapina | Greensman |
| Marc-Antoine Paquet | Sculptor |
| Éric Brais | Picture Car Coordinator |
| Maude Beaunoyer | Assistant Picture Car Coordinator |
| Jocelyne Hamel | Assistant Picture Car Coordinator |
| Yan Philie | Assistant Picture Car Coordinator |
| Claude Saingelain | Assistant Picture Car Coordinator |
| Péo Chénard | Transportation Coordinator |
| Philippe Gilbert | Transportation Captain |
| Michel Robert | Base Camp Operator |
| John-Sébastien Côté | Armorer |
| Joseph Petrucelli | Music Consultant |
| Steve Jordan | Music Consultant |
| Rhiannon Colley | Craft Service |
| Luc Champagne | Catering Head Chef |
| Sébastien Paré | Chef |
| Juan Pablo | Assistant Chef |
| Natalie Turgeon | Assistant Chef |
| Alexis Wiscomb | Post Production Supervisor |
| Michelle Fowler | Additional Post-Production Supervisor |
| Mallory Trice | Post Production Coordinator |
| Hughes Winborne | Additional Editing |
| Joe Leonard | Additional Editing |
| Kyle Falcon | First Assistant Editor |
| Ejon Williamson | Post Production Assistant |
| Samantha Hernandez | Post Production Assistant |
| Daniel Tantalean | Post Production Assistant |
| Dan Schrecker | Visual Effects Supervisor |
| Daniel Triller | Visual Effects Editor |
| Kelsey Schuyler | Post Production Accountant |
| Robert Hein | Supervising Sound Editor |
| Josh Berger | Sound Re-Recording Mixer |
| Robert Hein | Sound Re-Recording Mixer |
| Glenfield Payne | Sound Re-Recording Mixer |
| Glenfield Payne | Sound Effects Editor |
| Ian Cymore | Dialogue Editor |
| Dave Paterson | Dialogue Editor |
| Sylvia Menno | Dialogue Editor |
| Josh Berger | Dialogue Editor |
| Kenton Jakub | ADR Editor |
| Ruth Hernandez | ADR Editor |
| Dennis Dembeck | Assistant Sound Editor |
| Heikki Kossi | Foley Artist |
| Kari Vähäkuopus | Foley Mixer |
| Lars Halvorsen | Foley Editor |
| Bobby Johanson | ADR Mixer |
| Michael Rivera | ADR Recordist |
| Joel Scheuneman | Sound Engineer |
| Georgia Simon | ADR Voice Casting |
| Jen Monnar | Supervising Music Editor |
| Kris Bowers | Musician |
| Max Wrightson | Music Coordinator |
| Stephen Kaye | Scoring Mixer |
| Scott Michael Smith | Score Engineer |
| Edward Trybek | Orchestrator |
| Jonathan Beard | Orchestrator |
| Henri Wilkinson | Orchestrator |
| Fabrizio Mancinelli | Conductor |
| Moises Cruz | Digital Intermediate Producer |
| Rebecca Erbe | Digital Intermediate Producer |
| Tim Stipan | Colorist |
| Nick Nassif | Color Assistant |
| Alain Lachance | Visual Effects Supervisor |
| Loic Laurelut | Compositing Supervisor |
| Eric Clement | CG Supervisor |
| Marie-Claude Lafontaine | Visual Effects Producer |
| Mélissa Massé | Visual Effects Coordinator |
| Philippe Langlois | Matte Painter |
| Simon Beaupré | VFX Artist |
| Sébastien Chartier | VFX Artist |
| Valérie Dugas | VFX Artist |
| Bryan Hsu | VFX Artist |
| Andris Pakalns | VFX Artist |
| Raphael Valle | VFX Artist |
| Didier Bertrand | VFX Artist |
| Camille Dao | VFX Artist |
| Jessica Francoeur-Ducharme | VFX Artist |
| Maxime Lapointe | VFX Artist |
| Charles Richer | VFX Artist |
| Pierre-David Myles | VFX Artist |
| Jonathan Lancelot | Visual Effects Editor |
| Marc A. Rousseau | Executive Visual Effects Producer |
| Olivier Péloquin | Pipeline Technical Director |
| Kristyn Hume | Title Designer |
| Charles Gregory Ross | In Memory Of |
| Simon Paquin | Transportation Captain |
| Eboni Nichols | Choreographer |
| Pietu Korhonen | Foley Editor |
| Trevor Jones | Stunts |
