 | Amber Heard als Kristen |
 | Mamie Gummer als Emily |
 | Danielle Panabaker als Sarah |
 | Jared Harris als Dr. Stringer |
 | Laura-Leigh als Zoey |
 | Lyndsy Fonseca als Iris |
 | Mika Boorem als Alice Hudson |
 | Sydney Sweeney als Young Alice Hudson |
 | D.R. Anderson als Roy |
 | Susanna Burney als Nurse Lundt |
 | Sean Cook als Jimmy |
 | Jillian Kramer als Ghost Alice |
 | Milos Milicevic als Predator |
 | Sali Sayler als Tammy |
 | Mark Chamberlin als Mr. Hudson |
 | Andrea Petty als Mrs. Hudson |
 | Tracy Schornick als Cop#1 |
 | Kent Kimball als Cop #2 |
 | Patrick Treadway als 2nd Floor Nurse |
| Bev Holsclaw als Admitting nurse |
| Lonny W. Waddle als Orderly (uncredited) |
| Pam Dixon | Casting |
| John Carpenter | Director |
| Shawn Rasmussen | Writer |
| Lisa Caryl-Vukas | Costume Design |
| Andrew Spaulding | Producer |
| Paul Peters | Production Design |
| Peter Block | Producer |
| Mike Marcus | Producer |
| Patrick McMahon | Editor |
| Rachel M. Thompson | Set Decoration |
| Doug Mankoff | Producer |
| Trista Jordan | Makeup Department Head |
| Vincent DeFelice | Art Direction |
| Yaron Orbach | Director of Photography |
| Barbara Brown | Script Supervisor |
| Jeff Stone | First Assistant Editor |
| Charles Papert | Steadicam Operator |
| Pete Moroz | Still Photographer |
| Steve Broussard | Construction Coordinator |
| Tim Maffia | Digital Intermediate |
| Scott Kramer | Foley Editor |
| Rick Davidson | Additional Camera |
| Mike Meyers | Hairstylist |
| Brian Dunlop | Foley Editor |
| Lara Dale | Foley |
| Javier Bennassar | Sound Designer |
| Mandell Winter | Supervising Dialogue Editor |
| Amy Bruscoe | Makeup Artist |
| Tom Marks | Sound Re-Recording Mixer |
| Casey Pritchett | Special Effects Coordinator |
| Piotr Redlinski | Still Photographer |
| Taci Van Leuven | Hairstylist |
| Jennifer Popochock | Key Hair Stylist |
| Tim Limer | Sound Recordist |
| Jodi Nichols | Art Department Coordinator |
| Lynn Wegenka | First Assistant Director |
| Leslie Shatz | Sound Designer |
| Don Stier | Dolly Grip |
| Chris David | Sound Re-Recording Mixer |
| Gregory D. Smith | Key Grip |
| Michael Rasmussen | Writer |
| Mark Kilian | Original Music Composer |
| Jeff Imada | Stunt Coordinator |
| Helena Barrett | Stunt Double |
| Heidi Pascoe | Stunt Double |
| John Casino | Stunt Coordinator |
| Jillian Kramer | Stunts |
| Stacey Carino | Stunts |
| Michelle Sebek | Stunt Double |
| Mike Vukas | Gaffer |
