 | Felicity Huffman als Sabrina "Bree" Osbourne / Stanley Schupak |
 | Kevin Zegers als Toby Wilkins |
 | Fionnula Flanagan als Elizabeth Schupak |
 | Burt Young als Murray Schupak |
 | Carrie Preston als Sydney Schupak |
 | Elizabeth Peña als Margaret |
 | Graham Greene als Calvin Many Goats |
 | Venida Evans als Arletty |
 | Jon Budinoff als Alex |
 | Raynor Scheine als Bobby Jensen |
 | Danny Burstein als Dr. Spikowsky |
 | Maurice Orozco als Fernando |
 | Stella Maeve als Taylor |
 | Teala Dunn als Little Girl |
| Grant Monohon als Hitchhiker |
 | Paul Borghese als New York City Cop |
 | Andrea James als Voice Coach |
 | Amy Povich als Phoenix Cop |
 | Bianca Leigh als Mary Ellen |
 | Craig Bockhorn als Sergeant |
 | Kate Bayley als Tennessee Waitress |
| Jim Frangione als Taylor's Father |
| Calpernia Addams als Calpernia |
 | David E. Harrison als David |
 | Forrie J. Smith als Sammy |
 | Barbara Barron als Mrs. Swallow |
| Steve Hurwitz als Harvey |
 | Richard Poe als John |
| Vince Reign als Waiter |
| William H. Macy | Executive Producer |
| Duncan Tucker | Screenplay |
| Lucy Cooper | Line Producer |
| Karen O'Toole | Production Manager |
| Pam Wise | Editor |
| Rene Bastian | Producer |
| Lisa Scoppa | Set Decoration |
| Elinyisia Mosha | Production Manager |
| David Mansfield | Original Music Composer |
| Lucy Cooper | Producer |
| Mark White | Production Design |
| Duncan Tucker | Director |
| Eve Battaglia | Casting |
| Danny Glicker | Costume Design |
| Linda Moran | Producer |
| Stephen Kazmierski | Director of Photography |
| Lynn Campbell | Makeup & Hair |
| Jason Hayes | Wig Designer |
| Gerard Kelly | Wig Designer |
| Heidi Kulow | Makeup Department Head |
| Celia Hallquist | Production Manager |
| Justin Ritson | Second Second Assistant Director |
| Sebastian Mazzola | First Assistant Director |
| Urs Hirschbiegel | First Assistant Director |
| Lauren Guilmartin | Second Assistant Director |
| David Blazina | Additional Second Assistant Director |
| Neil Driscoll Jr. | Leadman |
| Kat Donahue | Set Dresser |
| Pastor Alvarado III | Assistant Property Master |
| Jeff Everett | Art Direction |
| Duke Scoppa | Property Master |
| Todd M. Serkland | Set Dresser |
| Emily Gaunt | Scenic Artist |
| Carlie Bergman | Assistant Foley Artist |
| Louis Bertini | Supervising Sound Editor |
| Leslie Bloome | Foley Artist |
| Laura Congleton | Assistant Sound Editor |
| David Diamond | Sound Mixer |
| Chris Fondulas | Boom Operator |
| Katherine Gordon Miller | Assistant Sound Editor |
| Douglas Murray | ADR Mixer |
| Griffin Richardson | Sound Recordist |
| Gabriel Sanders | Boom Operator |
| Tony Volante | Sound Re-Recording Mixer |
| Dave Corcoran | Sound Recordist |
| Manny Siverio | Stunt Coordinator |
| Lawrence Blume | Thanks |
| Brian David Cange | Thanks |
| Marília Pêra | Thanks |
| Laila Robins | Thanks |
| Barbara Sukowa | Thanks |
| Tom Camarda | Director of Photography |
| Jay Coolidge | Second Assistant Camera |
| Marialuisa Ernst | Lighting Technician |
| Bob Izzo | Key Grip |
| Jim Mickle | Best Boy Grip |
| Jessica Miglio | Still Photographer |
| Laura Nespola | Second Assistant Camera |
| Doug Oh | First Assistant Camera |
| Joseph Paolini | Grip |
| Eddie Rodriguez | First Assistant Director |
| Steve Siddell | Best Boy Electric |
| Jason Velez | Gaffer |
| Rafael Winer | Still Photographer |
| Gay Gilbert | Casting |
| Gil Kruger | Casting Assistant |
| Erika Munro | Wardrobe Supervisor |
| Joe Monge | Technical Supervisor |
| John Rehberger | Online Editor |
| Mara Safransky | Assistant Editor |
| Jane Tolmachyov | Colorist |
| Rebecca Fulton | Script Supervisor |
| David Mansfield | Musician |
| Doug Bernheim | Music Supervisor |
| Tony Diaz | Driver |
| George Swinney | Driver |
| Blake Davis | Set Production Assistant |
