 | Sheryl Lee als Laura Palmer |
 | Ray Wise als Leland Palmer |
 | Mädchen Amick als Shelly Johnson |
 | Dana Ashbrook als Bobby Briggs |
 | Phoebe Augustine als Ronette Pulaski |
 | David Bowie als Phillip Jeffries |
 | Eric DaRe als Leo Johnson |
 | Miguel Ferrer als Albert Rosenfield |
 | Pamela Gidley als Teresa Banks |
 | Heather Graham als Annie Blackburn |
 | Chris Isaak als Chester Desmond |
 | Moira Kelly als Donna Heyward |
 | Peggy Lipton als Norma Jennings |
 | David Lynch als Gordon Cole |
 | James Marshall als James Hurley |
 | Jürgen Prochnow als Woodsman |
 | Harry Dean Stanton als Carl Rodd |
 | Kiefer Sutherland als Sam Stanley |
 | Lenny Von Dohlen als Harold Smith |
 | Grace Zabriskie als Sarah Palmer |
 | Kyle MacLachlan als Dale Cooper |
 | Frances Bay als Mrs. Tremond (Chalfont) |
 | Catherine E. Coulson als The Log Lady |
 | Michael J. Anderson als Man From Another Place |
 | Frank Silva als Bob |
 | Walter Olkewicz als Jacques Renault |
 | Al Strobel als Philip Gerard (The One Armed Man) |
 | Gary Hershberger als Mike Nelson |
 | Sandra Kinder als Irene at Hap's |
 | Chris Pedersen als Tommy |
 | Victor Rivers als Buck |
 | Rick Aiello als Cliff Howard |
 | Gary Bullock als Sheriff Cable |
 | Jon Huck als FBI Agent |
| Mike Malone als FBI Agent |
| Joe Berman als Bus Driver |
| Yvonne Roberts als First Prostitute |
| Audra L. Cooper als Second Prostitute |
| John Hoobler als Pilot |
| Kimberly Anne Cole als Lil the Dancer |
| Elizabeth McCarthy als Giggling Secretary |
| C.H. Evans als Jack at Hap's |
| Paige Bennett als French Girl at Hap's |
| G. Kenneth Davidson als Old Guy at Hap's |
| Ingrid Brucato als Curious Woman |
| Chuck McQuary als Medic |
| Margaret Adams als Fat Trout Neighbor |
| Carlton Lee Russell als Jumping Man |
 | Calvin Lockhart als The Electrician |
| Jonathan J. Leppell als Mrs. Tremond's Grandson |
| David Brisbin als Second Woodsman |
 | Andrea Hays als Heidi |
 | Julee Cruise als Roadhouse Singer |
| Steven Hodges als Band at Roadhouse |
| William Ungerman als Band at Roadhouse |
| Joseph 'Simon' Szeibert als Band at Roadhouse |
| Smokey Hormel als Band at Roadhouse |
| Joseph L. Altruda als Band at Roadhouse |
 | James Parks als Service Station Mechanic |
| Jane Jones als School Teacher |
| Karin Robison als Angel in Train Car |
| Lorna MacMillan als Angel in Red Room |
| Philip Anagnos als Student (uncredited) |
 | Anne Gaybis als Dancer on Stage in 'Pink Room' (uncredited) |
| John Nelson als Double R Diner Customer (uncredited) |
| Gregg Fienberg | Producer |
| Ronald Víctor García | Director of Photography |
| David Lynch | Director |
| Mary Sweeney | Editor |
| Francis Bouygues | Producer |
| Angelo Badalamenti | Music |
| Sophia Barashkoff | Painter |
| Jon Kazunaga | Construction Foreman |
| Daniel Kuttner | Property Master |
| David Lynch | Sound Designer |
| Douglas Murray | Supervising Sound Editor |
| David Parker | Sound Re-Recording Mixer |
| Christopher Rohde | Visual Effects |
| Rufus Reid | Musician |
| Frank Canonica | Sound Recordist |
| Diana Wagner-Boyd | Stunts |
| Norbert F. Quiban | Electrician |
| Elaine J. Huzzar | Casting Associate |
| Heidi Walker | Casting |
| Cheri Reed | Set Costumer |
| Angelo Badalamenti | Orchestrator |
| Leslie Morales | Set Decoration |
| Stephen Kearney | Assistant Sound Editor |
| Del Reahm | Special Effects |
| John Buckley | Gaffer |
| Dan Kneece | Steadicam Operator |
| Stephen McGehee | Lighting Technician |
| Rick Wiley | Key Grip |
| James Hynes | Musician |
| Patricia Norris | Costume Design |
| Sabrina McCarthy | Special Effects |
| Darrell Pritchett | Special Effects |
| Vince Rapini | Grip |
| Eric Thomas | Electrician |
| Ron Carter | Musician |
| David Cooper | Musician |
| Marvin Perry | Carpenter |
| Carlos Quintero | Carpenter |
| Gunter Simon | Special Effects |
| Johanna Ray | Casting |
| Patricia Norris | Production Design |
| Phil Benson | Assistant Sound Editor |
| Kristen Gerstner | Assistant Sound Editor |
| Bob Rose | Musician |
| John Wentworth | Co-Producer |
| Mike Malone | Set Dresser |
| David E. Robinson | Scenic Artist |
| Bob Riggs | Special Effects Coordinator |
| Vinnie Bell | Musician |
| William Fairbanks | Musician |
| David Jaurequi | Musician |
| Art Polhemus | Scoring Mixer |
| Chris Kelly | Painter |
| Bob McCarthy | Special Effects Coordinator |
| Hannah Kozak | Stunts |
| Traci Clauson | Stand In |
| David Lynch | Executive Producer |
| Katharina Hirsch-Smith | Key Makeup Artist |
| John Canedo | Painter |
| Debbie Pinthus | Boom Operator |
| Kathleen Reilly | Stunts |
| Tasso Bravos | Grip |
| Lloyd Moriarity | Key Grip |
| Deborah Gavlak | First Assistant Editor |
| Dave Alvin | Musician |
| Myles Boisen | Musician |
| Steven Hodges | Musician |
| Dana Eskelson | Stand In |
| Morgan Flaherty | Carpenter |
| David Boushey | Stunts |
| Ryan Purcell | Grip |
| Kinny Landrum | Musician |
| David Slusser | Musician |
| Buster Williams | Musician |
| Tim Harbert | Associate Producer |
| Johanna Ray | Co-Producer |
| Jon Huck | Sound Recordist |
| Donny Miele | Sound Effects Editor |
| Stephen Les | Grip |
| Tom Marvel | Best Boy Electric |
| Lloyd Moriarity | Dolly Grip |
| Shade Rupe | Grip |
| Shannon Ward | Casting Assistant |
| Andy Armor | Musician |
| David Christopher Campbell | Carpenter |
| Keith Cox | Construction Coordinator |
| Jon H. Epstein | Stunt Coordinator |
| Jay Johnson | Electrician |
| Don Falzone | Musician |
| Mark Frost | Executive Producer |
| Richard F.W. Davis | Sound Effects Editor |
| James Lebrecht | Sound Effects Editor |
| Dan Olmsted | Sound Recordist |
| Terry Shattuck | Special Effects |
| Kyle Carver | Electrician |
| Amy Stofsky | Costume Supervisor |
| Joe Fineman | Post Production Consulting |
| Angelo Badalamenti | Musician |
| Donald Bailey | Musician |
| Lori L. Eschler | Music Editor |
| Al Regni | Musician |
| Grady Tate | Musician |
| Audrey Stanzler | Set Dresser |
| T.J. Williams | Steadicam Operator |
| Jay Hoggard | Musician |
| Cori Glazer | Script Supervisor |
| Brent Lavett | Hairstylist |
| Gregg Fienberg | Unit Production Manager |
| Deepak Nayar | First Assistant Director |
| Richard Oswald | Second Assistant Director |
| Tyler Dupuy | Carpenter |
| James 'Bud' Hays | Carpenter |
| William Buckingham III | Grip |
| Bruce Alan Greene | Steadicam Operator |
| Stephanie Sandston | Leadman |
| David Lynch | Sound Re-Recording Mixer |
| Michael Semanick | Sound Re-Recording Mixer |
| Jeff Smolek | Stunt Coordinator |
| Colleen Kingdon | Electrician |
| Miguel Rico | Electrician |
| Joe Montrone | Production Manager |
| Pierre Edelman | Thanks |
| Barry Littman | Stand In |
| Gaye Pope | Unit Publicist |
| Sean Doyle | Additional Photography |
| Barbara Harris | ADR Voice Casting |
| Angelo Badalamenti | Original Music Composer |
| Andrew Durham | Production Assistant |
| David Lynch | Writer |
| Robert Engels | Writer |
| Mark Frost | Original Series Creator |
| David Lynch | Original Series Creator |
| Mark Frost | Writer |
