 | Tom Hardy als Eddie Brock / Venom |
 | Michelle Williams als Anne Weying |
 | Riz Ahmed als Carlton Drake / Riot |
 | Scott Haze als Security Chief Roland Treece |
 | Reid Scott als Dr. Dan Lewis |
 | Jenny Slate als Dr. Dora Skirth |
 | Melora Walters als Homeless Woman Maria |
 | Woody Harrelson als Cletus Kasady / Carnage |
 | Peggy Lu als Mrs. Chen |
 | Malcolm C. Murray als Lewis Donate |
 | Sope Aluko als Dr. Collins |
 | Wayne Pére als Dr. Emerson |
 | Michelle Lee als Malaysia EMT / Riot Host |
 | Kurt Yue als Mission Control Translator |
 | Chris O'Hara als Astronaut J. J. Jameson III |
 | Emilio Rivera als Lobby Guard Richard |
 | Amelia Young als Allie |
 | Ariadne Joseph als Eddie's TV Producer |
| Deen Brooksher als Drake Interview Guard #1 |
| David Jones als Drake Interview Guard #2 |
 | Roger Yuan als Village Eel Shop Owner |
 | Woon Young Park als Malaysia Village Tough #1 |
| Patrick Chundah Chu als Malaysia Village Tough #2 |
 | Vickie Eng als Elderly Village Woman / Riot Host |
 | Mac Brandt als Jack the Bartender |
 | Nick Thune als Beardo at Bar |
 | Michael Dennis Hill als Reporter on TV |
 | Sam Medina als Shakedown Thug |
 | Scott Deckert als Noisy Neighbor Ziggy |
 | Lauren Richards als Ziggy's Girlfriend |
 | Jared Bankens als Isaac / Blue Host |
 | Lucas Fleischer als Guard at Gate |
 | Michael Burgess als Flight Technician |
 | Diesel Madkins als Lab Security Guard |
 | Otis Winston als Chasing Guard |
 | Zeva DuVall als Little Girl / Riot Host |
 | Selena Anduze als Bistro Manager |
 | Brittany L. Smith als Bistro Hostess |
 | Jordan Foster als Waiter |
 | Jane McNeill als Diner #1 |
 | Victor McCay als Diner #2 |
 | Elizabeth Becka als Diner #3 |
 | Ron Prather als Diner #4 |
| Marcia White als Diner #5 |
 | Javier Vazquez Jr. als MRI Tech |
 | Ellen Gerstein als Hospital Lady with Dog / Mrs. Manfredi |
 | Martin Bats Bradford als Jacob / Blue Host |
 | Steven Teuchert als Stoner Dude #1 |
 | Al-Jaleel Knox als Stoner Dude #2 |
 | Brandon Morales als Crowd Control Officer |
 | Matthew Cornwell als Ops Director |
| David Fleischer als Flight Trajectory Specialist |
 | DJames Jones als L. F. Security Guard |
 | Angela Davis als Evacuating Scientist |
 | Stan Lee als Dapper Dog Walker |
 | Wade Williams als Prison Guard |
 | Ron Cephas Jones als Jack |
 | Christian Convery als Joey - 8 Year Old Boy (uncredited) |
 | Boston Rush Freeman als Trolly Teen #1 (uncredited) |
| Scott Rosenberg | Screenplay |
| Jeff Pinkner | Screenplay |
| David Michelinie | Characters |
| Matt Tolmach | Producer |
| Todd McFarlane | Characters |
| Avi Arad | Producer |
| Amy Pascal | Producer |
| Ruben Fleischer | Director |
| Kelly Marcel | Screenplay |
| Kelli Jones | Costume Design |
| Matthew Libatique | Director of Photography |
| Ludwig Göransson | Original Music Composer |
| David B. Householter | Executive Producer |
| Edward Cheng | Executive Producer |
| Jeff Pinkner | Screenstory |
| Howard Chen | Executive Producer |
| Stan Lee | Executive Producer |
| Scott Rosenberg | Screenstory |
| Tom Hardy | Executive Producer |
| Kelly Marcel | Executive Producer |
| Brice R. Parker | Visual Effects Production Manager |
| Alan Baumgarten | Editor |
| Maryann Brandon | Editor |
| Matt Gendron | Art Direction |
| Sheena Duggal | Visual Effects Supervisor |
| Chris O'Hara | Stunt Coordinator |
| Brandon Beckman | Stunts |
| Paul J. Franklin | Visual Effects Supervisor |
| Gabe Hilfer | Music Supervisor |
| Chad Bowman | Stunts |
| Matthew R. Anderson | Stunts |
| Ben Aycrigg | Stunts |
| Loyd Bateman | Stunts |
| Oliver Scholl | Production Design |
| John Papsidera | Casting |
| Spiro Razatos | Second Unit Director |
| Gregory J. Barnett | Stunts |
| Spiro Razatos | Stunt Coordinator |
| Keith Adams | Stunts |
| David Conk | Stunts |
| Phil Culotta | Stunts |
| Wally Crowder | Stunts |
| Joe Bucaro III | Stunts |
| RJ Casey | Stunts |
| Erik Cord | Stunts |
| Jahnel Curfman | Stunts |
| Cory DeMeyers | Stunts |
| Troy Sizemore | Art Direction |
| James F. Truesdale | Art Direction |
| Christophe Couzon | Art Direction |
| Diane Durant | Script Supervisor |
| Ron Licari | Armorer |
| Alice Felton | Set Decoration |
| Frédéric North | Aerial Coordinator |
| Gregory S. Hooper | Art Direction |
| Dea Cantu | Script Supervisor |
| Mari Wilson | Script Supervisor |
| Drew Monahan | Art Direction |
| Doug Fick | Art Direction |
| Brian Adler | Visual Effects |
| Larry Dias | Set Decoration |
| Aviv Bar-Ami | VFX Artist |
| Dana Robin | Unit Production Manager |
| David B. Householter | Unit Production Manager |
| Josh Roth | Property Master |
| K.C. Hodenfield | First Assistant Director |
| Michael Saunders | Second Assistant Director |
| Christopher TJ McGuire | "A" Camera Operator |
| Stewart Smith | "B" Camera Operator |
| John Holmes | First Assistant "A" Camera |
| Jeffrey N. Civa | First Assistant "B" Camera |
| Joey O'Donnell | Second Assistant "A" Camera |
| Bill McConnell Jr. | Second Assistant "B" Camera |
| Nicholas Kay | Digital Imaging Technician |
| Nick Cannon | Camera Loader |
| Michael-Ryan Fletchall | Drone Pilot |
| Jason Kay | Drone Operator |
| Ashley Heathcock | Assistant Costume Designer |
| Bill Edwards | Costume Supervisor |
| Jimmy Jay | Key Costumer |
| Harlan Groom | Key Costumer |
| Bree Tomlinson | Costume Coordinator |
| Kate Abraham | Costumer |
| Dustin Fletcher | Costumer |
| Gina Nalli | Costumer |
| Kate Duke | Costumer |
| Jay Wejebe | Makeup Department Head |
| Aida Scuffle | Key Makeup Artist |
| Audrey Doyle | Makeup Artist |
| Audrey Doyle | Prosthetic Makeup Artist |
| Angela Levin | Makeup Artist |
| Kayleen McAdams | Makeup Artist |
| Jordan Venetis | Makeup Artist |
| Jonah Levy | Prosthetic Makeup Artist |
| Matthew Silva | Prosthetic Makeup Artist |
| Adruitha Lee | Hair Department Head |
| Mary Everett | Key Hair Stylist |
| Tiffany Lord | Hairstylist |
| Tracie Morrison | Hairstylist |
| Dan Cornwall | Gaffer |
| Dale Fowler | Best Boy Electric |
| Clyde Sharman | Lighting Technician |
| Rusty Edmonson | Lighting Technician |
| Adam Harrison | Rigging Gaffer |
| Kerry Rawlins | Key Grip |
| Geoff Bremner | Best Boy Grip |
| Jeff 'Moose' Howery | Dolly Grip |
| Darryl Humber | Dolly Grip |
| Cordis Brooks | Grip |
| Keith Gaynor | Grip |
| Luke Messick | Grip |
| Matt Irby | Grip |
| Michael Cape | Grip |
| Mike Black | Grip |
| Chris Lumpkin | Rigging Grip |
| Matthew C. McCarthy | Rigging Grip |
| Matt Shearer | Rigging Supervisor |
| Michael B. Koff | Production Sound Mixer |
| Ian Bender | Boom Operator |
| Maria T. Bierniak | Location Manager |
| Caleb Hinshaw | Location Manager |
| Cait Murray | Assistant Location Manager |
| Georgia Anne Thompson | Assistant Location Manager |
| Justin M. Hamilton | Assistant Location Manager |
| Aaron D. Newton | Assistant Location Manager |
| Aaron J. Porter | Assistant Location Manager |
| Erin Burns | Assistant Location Manager |
| Marjorie Rudick | Production Coordinator |
| Huxley Rodriguez | Assistant Production Coordinator |
| Lacie Collins | Assistant Production Coordinator |
| Allen E. Taylor | Production Controller |
| Cheri Hall | Production Accountant |
| Steven DeSantis | Construction Coordinator |
| Nathan Krochmal | Assistant Art Director |
| Kristen Nowotarski | Assistant Art Director |
| Brian Baker | Set Designer |
| C. Scott Baker | Set Designer |
| Julie Vash | Set Designer |
| Omar Foster | Set Designer |
| Benton Jew | Storyboard Artist |
| Dan Sweetman | Storyboard Artist |
| David E. Duncan | Storyboard Artist |
| John Coven | Storyboard Artist |
| Monty Granito | Storyboard Artist |
| Ray Harvie | Storyboard Artist |
| Monica Fedrick | Graphic Designer |
| Wylie Griffin | Art Department Coordinator |
| Margaret Hungerford | Assistant Set Decoration |
| Max Bozeman | Assistant Property Master |
| Claire Raskind | Unit Publicist |
| Frank Masi | Still Photographer |
| Alina Gatti | Second Second Assistant Director |
| Caitlin Well | Casting Associate |
| Marissa Blair | Casting Assistant |
| Rose Locke | Extras Casting |
| Elizabeth Guiberteau | Craft Service |
| Robert Foster Jr. | Transportation Coordinator |
| Hector Tapia | Transportation Captain |
| Dennis Hallman | Transportation Co-Captain |
| Ben Cox | First Assistant Editor |
| Jane Tones | First Assistant Editor |
| Charlie B. Spaht | First Assistant Editor |
| Lindsay Tessier | Assistant Editor |
| Sumiko Braun | Post Production Coordinator |
| Kevin O'Connell | Sound Re-Recording Mixer |
| Will Files | Sound Re-Recording Mixer |
| Will Files | Sound Designer |
| Will Files | Supervising Sound Editor |
| Robert Stambler | Sound Designer |
| Ken McGill | Sound Effects Editor |
| Chris Terhune | Sound Effects Editor |
| Erin Oakley | ADR & Dubbing |
| Robert Chen | Dialogue Editor |
| Scott Ferrara | Dialogue Editor |
| Tim Tuchrello | Assistant Sound Editor |
| Ailene Roberts | Assistant Sound Editor |
| Sarah Monat | Foley Artist |
| Robin Harlan | Foley Artist |
| Gary A. Hecker | Foley Artist |
| Michael J. Broomberg | Foley Artist |
| Nerses Gezalyan | Foley Mixer |
| Randy Singer | Foley Mixer |
| Aaron Hasson | ADR Mixer |
| Howard London | ADR Mixer |
| Amanda Goodpaster | Music Editor |
| Joe Lisanti | Music Editor |
| Scott Johnson | Music Editor |
| Edward Trybek | Conductor |
| Henri Wilkinson | Orchestrator |
| Jonathan Beard | Orchestrator |
| Christoph Westphal | VFX Artist |
| Gary Archer | Prosthetics |
| Marie-France Henri | Digital Compositor |
| James David Leal | Set Costumer |
| Kelly Róisín | Stunts |
| Charlie Picerni | Stunt Driver |
| Henry Kingi | Stunt Driver |
| Andy Gill | Stunt Coordinator |
| Jack Gill | Stunt Coordinator |
| Katie Gill | Stunts |
| Denney Pierce | Stunts |
| Mike Malone | Set Dresser |
| Jimmy N. Roberts | Stunt Double |
| Monique Ganderton | Stunts |
| Daniel Hargrave | Stunts |
| Dane Farwell | Stunts |
| Steve Kelso | Stunt Driver |
| Todd Harris | Storyboard Artist |
| Allan Padelford | Stunt Driver |
