 | Jason Sudeikis als David Clark |
 | Jennifer Aniston als Rose O'Reilly |
 | Emma Roberts als Casey Mathis |
 | Will Poulter als Kenny Rossmore |
 | Ed Helms als Brad Gurdlinger |
 | Nick Offerman als Don Fitzgerald |
 | Kathryn Hahn als Edie Fitzgerald |
 | Molly C. Quinn als Melissa Fitzgerald |
 | Tomer Sisley als Pablo Chacon |
 | Matthew Willig als One-Eye |
 | Luis Guzmán als Mexican Cop |
 | Thomas Lennon als Rick Nathanson |
 | Mark L. Young als Scottie P. |
 | Ken Marino als Todd - Strip Club Owner |
 | Laura-Leigh als Kymberly |
 | Crystal Nichol als Brad's Receptionist |
 | Dickson Obahor als Parking Cop |
 | Brett Gentile als White Bread Dad |
 | Kelly Collins Lintz als White Bread Mom |
 | Sam Richardson als TSA Agent |
 | Lynn Talley als Stylist |
 | Alan Gilmer als Middle Aged Man |
 | Denielle Fisher Johnson als Flight Attendant #1 |
 | Deborah Chavez als Flight Attendant #2 |
 | Kevin Dorff als Border Guard #1 |
 | Rawson Marshall Thurber als The Ultimate Border Guard |
 | Kurt Grossi als Border Guard #3 |
 | Dave McElhaney als White Gringo |
 | Brendan Hunt als Sketchy Dude |
 | Scott Adsit als Doctor |
 | Vickie Eng als Hospital Nurse |
 | Lunden De'Leon als Hospital Receptionist |
 | Joey Nappo als Gutter Punk #1 |
 | Joshua Mikel als Gutter Punk #2 |
 | Matt Schweppe als Gutter Punk #3 |
 | Tonya Bludsworth als Soccer Mom |
 | Matthew Cornwell als Dan Johnson |
 | Marcus Viscidi als Business Man |
| Andrea Alcorn als Fair Goer (uncredited) |
| Martin Edward Andazola als Mexican Federali - SWAT (uncredited) |
 | Loren Anthony als Mexican Border Crosser (uncredited) |
 | Joshua R. Aragon als Drug Cartel Member (uncredited) |
 | Lionel Archuleta als Mexican Pedestrian (uncredited) |
| Laura Avery als Fair Goer (uncredited) |
| Del Baron als Coffee Shop Patron (uncredited) |
| Alyssa Bauman als Pedestrian (uncredited) |
| Christine Bear als Strip Club Cocktail Waitress (uncredited) |
 | Jenique Bennett als Stripper (uncredited) |
 | Ashley Blankenship als Hot Tub Bikini Girlfriend (uncredited) |
 | Kristi Booher als Pedestrian (uncredited) |
| Rachel Brewer als Fair Goer (uncredited) |
| Crystal M. Craven als DEA Agent (uncredited) |
 | Robert Crayton als Kidnapper (uncredited) |
| Christian Daniels als Fair Goer (uncredited) |
 | Lindsay Davis als Hot Tub Girlfriend (uncredited) |
| Todd Davis als Pedestrian (uncredited) |
| Michael J. Flanagan als Strip Club Patron (uncredited) |
 | Tait Fletcher als Creepy Trucker (uncredited) |
| Lauren Frandsen als Exotic Dancer (uncredited) |
 | William Frasca als Pedestrian (uncredited) |
 | Amanda Fresquez als Airplane Passenger (uncredited) |
 | Lawrence Gilligan als Border Guard (uncredited) |
| Randy Grazio als Neighbor (uncredited) |
| Albert Guzman als Fair Goer (uncredited) |
| Rebecca Harran als Fair Goer (uncredited) |
 | Karen M. Hudson als Border Crosser (uncredited) |
| Joe W. Lacey als Strip Club Patron (uncredited) |
| Saeri Lee als Pedestrian (uncredited) |
 | Natalia Marie als Stripper (uncredited) |
 | Cathy Mattson als Fair Goer (uncredited) |
| Brian Patrick Moize als Strip Club Bouncer (uncredited) |
| Robb Moon als Airline Passenger (uncredited) |
| Patrick V. Murphy als Mexican Taxi Driver (uncredited) |
| Matt Perkinson als Strip Club Patron (uncredited) |
| Danny Pollack als Strip Club Patron (uncredited) |
| Ed Ricker als Fair Goer (uncredited) |
 | John Henry Scott als Stilt Walker (uncredited) |
| Amanda Quinn Sherrick als Fair Goer (uncredited) |
| Bernard Sintim als Upscale Bistro Diner (uncredited) |
| Nathan Marcus Smith als Coffee Shop Patron (uncredited) |
| Michael E. Stogner als Airline Passenger (uncredited) |
| Nick Thies als Fair Goer (uncredited) |
| Shane Thompson als Strip Club Patron (uncredited) |
| Melissa Veal als Fair Goer (uncredited) |
 | Millie Wannamaker als Hospital Visitor (uncredited) |
| Anthony Williams als DEA Agent (uncredited) |
| Tyler Gene als Fair Goer (uncredited) |
| Rawson Marshall Thurber | Director |
| Chris Bender | Producer |
| Vincent Newman | Producer |
| Tucker Tooley | Producer |
| Happy Walters | Producer |
| Edward Pelle | Producer |
| Bob Fisher | Screenplay |
| Steve Faber | Screenplay |
| Sean Anders | Screenplay |
| John Morris | Screenplay |
| Bob Fisher | Story |
| Steve Faber | Story |
| Ludwig Göransson | Original Music Composer |
| Theodore Shapiro | Original Music Composer |
| Barry Peterson | Director of Photography |
| Michael L. Sale | Editor |
| Clayton Hartley | Production Design |
| Ronald J. Webb | Music Editor |
| Lisa Beach | Casting |
| Sarah Katzman | Casting |
| Elliott Glick | Art Direction |
| Chuck Potter | Set Decoration |
| Shay Cunliffe | Costume Design |
| Claire Hallworth | Costume Design |
| Nina Hallworth | Costume Design |
| Lindsey Suggs | Art Department Coordinator |
| Thomas A. Morris Jr. | Construction Coordinator |
| Robert Tezai | Visual Effects Coordinator |
| Jeremy Gordon | Casting Associate |
| Katie Saunders | Costume Supervisor |
| Shaun Garcia | Set Costumer |
| Lisa Hill | Set Costumer |
| Teri-Lyn Pugliese | Set Costumer |
| Michaell Keith Taylor Jr. | Set Costumer |
| Denise Faye | Choreographer |
| Patricia McAlhany Glasser | Hair Department Head |
| Christina Raye | Key Hair Stylist |
| Ashton Glasser | Key Hair Stylist |
| Whitney James | Makeup Department Head |
| Desne J. Holland | Makeup Artist |
| Claudia Pascual | Makeup Artist |
| Angela Levin | Makeup Artist |
| Richard Brener | Executive Producer |
| Toby Emmerich | Executive Producer |
| David Heyman | Executive Producer |
| Patrick McIntire | Consulting Producer |
| Dave Neustadter | Executive Producer |
| J.C. Spink | Executive Producer |
| Marcus Viscidi | Executive Producer |
| Matt Weaver | Co-Producer |
| Will Weiske | Unit Production Manager |
| John Burton West | Production Supervisor |
| Dee Blackburn | Set Designer |
| Ricardo Guillermo | Set Designer |
| Alex McCarroll | Set Designer |
| Beth Lipari | Casting Associate |
| Kevin Andrews | Location Manager |
| Robin Citrin | Location Manager |
| Paul B. Roberts | Location Scout |
| Elizabeth A. Dennis | Production Coordinator |
| Nancy Honeycutt | Production Coordinator |
| Crystal McAlerney | Production Coordinator |
| Grady Allen Bishop | Stunt Driver |
| Derrick Ballard | Set Designer |
| Erica Fester | Set Dresser |
| Jeffrey A. Hughes | Set Dresser |
| Vincent E. Immordino | Set Dresser |
| Patrick Jackson | Set Dresser |
| Edward McLoughlin | Set Decoration Buyer |
| Chris Painter | Set Dresser |
| George H. Anderson | Supervising Sound Editor |
| Cindy Marty | Sound Effects Editor |
| Brad Sherman | Sound Re-Recording Mixer |
| Elmo Weber | Sound Re-Recording Mixer |
| David D. Johnson | Visual Effects Supervisor |
| Andrew Lewitin | Visual Effects |
| Loeng Wong-Savun | VFX Artist |
| Laurie Singer | Stunt Double |
| Michele Waitman | Stunt Double |
| Kym Stys | Stunt Driver |
