 | Tim Allen als Jack Sheppard |
 | Courteney Cox als Marsha Holloway |
 | Chevy Chase als Dr. Grant |
 | Spencer Breslin als Tucker Willams / Mega-Boy |
 | Kevin Zegers als Connor Shepard / Concussion |
 | Kate Mara als Summer Jones / Wonder |
 | Michael Cassidy als Dylan West / Houdini |
 | Ryan Whitney Newman als Cindy Collins / Princess |
 | Rip Torn als Larraby |
 | Cornelia Guest als Cindy's Mom |
 | Ashton Moio als Halloween Bully |
 | Hunter Aarniokoski als Prince |
 | Thomas F. Wilson als Dylan's Teacher |
 | Ridge Canipe als Mean Bully |
 | Danny McCarthy als Meaner Bully |
 | David L. Lander als Wendy's Employee |
 | Lauren Sánchez als Reporter |
 | Willie Garson als Dick |
| Jane Hajduk als Researcher Taylor |
| Tommy Chang als Martial Arts Instructor |
 | Zoe Doyle als Researcher |
| Jennifer Todd | Producer |
| Suzanne Todd | Producer |
| John Papsidera | Casting |
| David Tattersall | Director of Photography |
| Neil A. Machlis | Executive Producer |
| Todd Garner | Producer |
| Mark Owen Forker | Visual Effects Supervisor |
| Ha Nguyen | Costume Design |
| Barry Chusid | Production Design |
| Peter Hewitt | Director |
| Tamara Deverell | Art Direction |
| Christophe Beck | Original Music Composer |
| Clive Thomasson | Set Decoration |
| Nick Osborne | Executive Producer |
| Lawrence Jordan | Editor |
| Adam Rifkin | Screenplay |
| Adam Rifkin | Screenstory |
| David Berenbaum | Screenplay |
| Joshu de Cartier | Art Direction |
| Matthew Wood | Supervising Sound Editor |
| Trevor Engelson | Executive Producer |
| Tim Merkel | Steadicam Operator |
| Joseph Boccia | Associate Producer |
| Virginia Burton | Costume Supervisor |
| Shelley Cook | Stunt Driver |
| Mark Dornfeld | Visual Effects Supervisor |
| Susan Marucci | Script Supervisor |
| Chris Scarabosio | Sound Designer |
| Ava Gerlitz | Still Photographer |
| Angie Jones | Animation |
| Jason Lethcoe | Novel |
| Julie Ragland | Co-Producer |
| Robert Scherer | Production Sound Mixer |
| Lisa Shaftel | Property Master |
| Luci Romberg | Stunts |
