 | Scott Mechlowicz als Scott Thomas |
 | Jacob Pitts als Cooper Harris |
 | Travis Wester als Jamie |
 | Michelle Trachtenberg als Jenny |
 | Jessica Boehrs als Mieke |
 | Kristin Kreuk als Fiona |
 | Vinnie Jones als Mad Maynard |
 | Dominic Raacke als Trucker |
 | Jana Pallaske als Anna, The Camera Store Girl |
 | Nial Iskhakov als Bert |
 | Petr Jákl als Gunter |
 | Molly Schade als Candy |
 | Jakki Degg als Missy |
 | Lenka Dayrit als Sissy |
| Cathy Meils als Mrs. Thomas |
 | J.P. Manoux als Robot Man |
| Patrick Rapold als Christoph |
 | Fred Armisen als Creepy Italian Guy |
 | Lucy Lawless als Madame Vandersexxx |
 | Diedrich Bader als Mugger |
 | Rade Šerbedžija als Tibor |
 | Jan Nemejovský als Manager at Opulent Hotel |
 | Miroslav Táborský als Waiter at Opulent Hotel |
 | Matt Damon als Donny |
 | Steve Hytner als Green Fairy |
 | Walter Sittler als Mieke's Father |
 | Patrick Malahide als Arthur Frommer |
| Ellen Savaria als Tourist Woman in Vatican |
| Predrag Bjelac als Italian Guy at Vatican |
 | Pat Kilbane als American Robot Guy |
 | Joanna Lumley als Hostel Clerk |
 | Mindy Sterling als Old Woman in Confessional (uncredited) |
 | Jeffrey Tambor als Scott's Dad (uncredited) |
 | Tereza Zimova als Vandersexxx Girl |
 | Lucie Kachtikova als Vandersexxx Girl |
 | Barbora Navratilova als Vandersexxx Girl |
| Joe Medjuck | Executive Producer |
| Roger Bondelli | Editor |
| Jackie Marcus Schaffer | Producer |
| Alec Berg | Producer |
| Jeff Schaffer | Director |
| Tom Pollock | Executive Producer |
| David Mandel | Producer |
| Ivan Reitman | Executive Producer |
| Daniel Goldberg | Producer |
| David Eggby | Director of Photography |
| Meg Liberman | Casting |
| Dell Hake | Orchestrator |
| Harimander Singh Khalsa | Digital Compositors |
| Láďa Koranda | Standby Painter |
| Mike Wike | Stand In |
| Nada Pinter | Script Supervisor |
| Erin Michael Rettig | Sound Engineer |
| James L. Venable | Original Music Composer |
| Vanessa Vogel | Costume Design |
| Helena Šteidlová | Hairstylist |
| David Meeking | Scenic Artist |
| Jessica Bouz | Production Coordinator |
| Roman Rigo | Boom Operator |
| Reinhard Stergar | Production Sound Mixer |
| John Benson | Supervising Sound Editor |
| Allan Starski | Production Design |
| Jindřich Kočí | Art Direction |
| William A. Cimino | Set Decoration |
| Barbora Bucharová | Set Designer |
| John Marzano | Helicopter Camera |
| Klaus Fuxjäger | Camera Operator |
| Václav Kocman | Driver |
| Jarda Peterka | Stunt Coordinator |
| Martin C. Heselov | First Assistant Editor |
| Jan Borůvka | Gaffer |
| David Baxa | Art Direction |
| Lee Wimer | Color Timer |
| Richard Kroll | Researcher |
| Ravi Dube | Picture Car Coordinator |
| Pavel Čáslavský | Rigging Gaffer |
| Jiří Čtvrtečka | Rigging Grip |
| Mark Graziano | Post Production Supervisor |
| Kate Caldwell | Casting Associate |
| Sheila Allen | Production Accountant |
| Nenad Pečur | Art Direction |
| Jiří Macke | Set Decoration |
| Katerina van Gemundova | Art Department Coordinator |
| Jan Kodera | Leadman |
| Alisa Buckley | Unit Publicist |
| Martina Burgetová | Production Manager |
| Nelia Morago | Casting |
| Julia Caston | Costume Design |
| Erin Julie Tavin | Assistant Costume Designer |
| Adam Barnhart | Stunts |
| Milan Jáchym | Electrician |
| Gary R. Wordham | Production Supervisor |
| Hana Kučerová | Costume Supervisor |
| Bob Newlan | Sound Editor |
| Brian Thomas Nist | Sound Effects Editor |
| Rene Mikan | Sound Mixer |
| David Minkowski | Associate Producer |
| Kirk Chiswell | First Assistant Camera |
| Zdeněk Vávra | Still Photographer |
| Stanton Cruse | Supervising Animator |
| Pavel Voráček | Transportation Captain |
| Lukáš Bech | Location Manager |
| Patrick Houlihan | Music Supervisor |
| Jonathan Spencer Levy | Visual Effects |
| Chris Del Conte | Visual Effects Producer |
| Tom Karnowski | Unit Production Manager |
| Kevin Blank | Visual Effects Supervisor |
| Matthew Stillman | Associate Producer |
| Milena Koubková | Assistant Art Director |
| Lori McCoy-Bell | Hair Department Head |
| Tomáš Červenka | Cableman |
| Jiří Husák | Transportation Coordinator |
| Cami Patton | Casting |
| Peter McCaffrey | Steadicam Operator |
| Aileen Seaton | Key Hair Stylist |
| Larisa Šrámková | Seamstress |
| Lee Frazier | Post Production Assistant |
| Jim Turner | Production Controller |
| James Bolt | Sound Re-Recording Mixer |
| Greg Franklin | Animation Director |
| Jeff Schaffer | Writer |
| David Mandel | Writer |
| Alec Berg | Writer |
| Tom Karnowski | Co-Producer |
| Bára Barová | Set Dresser |
| Václav Kareš | Camera Loader |
| Ivo Grešák | Key Grip |
| Justin Mitchell | 3D Artist |
| Mirek Lux | First Assistant Director |
| Jiří Farkaš | Key Makeup Artist |
| John Kuchera | Dolly Grip |
| Jindřich Hanzl | Grip |
| Goran Uljanic | Assistant Production Coordinator |
| Gary Burritt | Negative Cutter |
| James Thatcher | Musician |
| Michael T. Ryan | Supervising Music Editor |
| Robert Morrisey | Assistant Sound Editor |
| Ray Felipe | Script Researcher |
| Marc Wolff | Pilot |
| Julie Harkin | Casting Assistant |
| Bobo Sobotka | Makeup Artist |
| Ben Howarth | Second Assistant Director |
| Lukáš Líbal | Third Assistant Director |
| Matthew Harrison | Foley Editor |
| Nancy Bishop | Local Casting |
| Helen Luttrell | Dialogue Editor |
| Ralph Osborn | Dialogue Editor |
| Tim Gomillion | Sound Recordist |
| Michal Svoboda | Property Master |
| Eva Ungrová-Malíková | Makeup & Hair |
| Jeff Gomillion | ADR Mixer |
| Igor Jelen | Assistant Chief Lighting Technician |
| Martin Cigler | Production Assistant |
| John Houlihan | Music Consultant |
| Barbara Branch | First Assistant Accountant |
| Gabi Brown | Costume Assistant |
| Ted Boonthanakit | Storyboard Artist |
| Lukas Bergmann | Assistant Picture Car Coordinator |
| Jan Kotik | Graphic Designer |
| Michal Abraham | Swing |
| Eric Chauvin | Matte Painter |
| Zuzana Bursíková | Costumer |
| Scott Curtis | Foley Supervisor |
| Pavel Policar | Special Effects Technician |
| Dale Wyatt | Dialogue Coach |
| Martin Hubáček | Assistant Editor |
| Andrea Bystrá | Assistant Location Manager |
| Steven R. Molen | Production Executive |
| Helena Frankova | Second Second Assistant Director |
| Philip Rogers | ADR Recordist |
| Jan Loukota | Stunt Double |
| Jan Cabalka | Second Assistant Camera |
| Ivo Červenka | Best Boy Grip |
| Jiří Severa | Extras Casting Coordinator |
| Jakub Zíka | Payroll Accountant |
| Veronika Gavlakova | Production Secretary |
| Jirí Hrstka | Extras Casting |
| Kamil Jaffar | Special Effects Supervisor |
| Richard Steven Horvitz | ADR Voice Casting |
| John T. Sweeney | Production Coordinator |
| Cinda-Lin James | Stunts |
| Miroslav Lhotka | Stunts |
| Lee Sheward | Stunt Coordinator |
| Pat Romano | Stunt Coordinator |
| Ivan Mareš | Stunts |
| Rene Hajek | Stunts |
| Frantisek Deak | Stunts |
| Steve Griffin | Stunts |
