 | Neel Sethi als Mowgli |
 | Bill Murray als Baloo (voice) |
 | Ben Kingsley als Bagheera (voice) |
 | Idris Elba als Shere Khan (voice) |
 | Scarlett Johansson als Kaa (voice) |
 | Christopher Walken als King Louie (voice) |
 | Lupita Nyong'o als Raksha (voice) |
 | Giancarlo Esposito als Akela (voice) |
 | Garry Shandling als Ikki (voice) |
 | Emjay Anthony als Young Wolf #1 (voice) |
 | Brighton Rose als Gray (voice) |
 | Jon Favreau als Pygmy Hog (voice) |
 | Sam Raimi als Giant Squirrel (voice) |
 | Russell Peters als Rocky the Rhino (voice) |
| Max Favreau als Young Wolf #2 (voice) |
| Chloe Hechter als Young Wolf #3 (voice) |
 | Asher Blinkoff als Young Wolf #4 (voice) |
| Knox Gagnon als Young Wolf #5 (voice) |
| Sasha Schreiber als Young Wolf #6 (voice) |
| Kai Schreiber als Young Wolf #7 (voice) |
| Madeleine Favreau als Raquel the Rhino (voice) |
 | Ritesh Rajan als Infant Mowgli's Father |
| Kendrick Reyes als Infant Mowgli |
 | Sara Arrington als Neelgai Deer (voice) |
| Artie Esposito als Animal Voices (voice) |
 | Allan Trautman als Animal Voices (voice) |
 | Dee Bradley Baker als Animal Voices (voice) |
| Sean W. Johnson als Animal Voices (voice) |
 | Daz Crawford als Shere Kahn (mo-cap) (uncredited) |
| Jon Favreau | Director |
| Seth Engstrom | Conceptual Design |
| Mark S. Wright | Visual Effects Editor |
| Robert Legato | Visual Effects Supervisor |
| Molly Allen | Executive Producer |
| Jon Favreau | Producer |
| Justin Marks | Screenplay |
| Laura Jean Shannon | Costume Design |
| Mark Livolsi | Editor |
| Karen Gilchrist | Executive Producer |
| Peter M. Tobyansen | Executive Producer |
| Brigham Taylor | Producer |
| Christopher Glass | Production Design |
| Bill Pope | Director of Photography |
| Kevin Kaska | Orchestrator |
| John Bartnicki | Co-Producer |
| Ravi Bansal | Art Direction |
| John Lord Booth III | Art Direction |
| Joyce Cox | Co-Producer |
| Andrew L. Jones | Supervising Art Director |
| Amanda Moss Serino | Set Decoration |
| Dan Lemmon | Visual Effects Supervisor |
| Adam Valdez | Visual Effects Supervisor |
| Rudyard Kipling | Novel |
| Marie Larkin | Hair Department Head |
| David M. Bernstein | Unit Production Manager |
| Margie Kaklamanos | Special Effects Makeup Artist |
| Gregory J. Pawlik Jr. | Second Assistant Director |
| Bryn E. Leetch | Key Hair Stylist |
| David H. Venghaus Jr. | Unit Production Manager |
| David H. Venghaus Jr. | First Assistant Director |
| Sarah Halley Finn | Casting Director |
| George Black | Key Makeup Artist |
| Jerad Marantz | Concept Artist |
| Richard M. Sherman | Songs |
| Robert B. Sherman | Songs |
| Bruce Franklin | Visual Effects Production Manager |
| Phil Langone | Storyboard Artist |
| Sally Potters | Assistant Production Coordinator |
| Garry Shandling | In Memory Of |
| Christopher Ferguson | Lighting Technician |
| Casey O'Neill | Stunt Coordinator |
| Lois Yaroshefsky | Studio Teacher |
| John Debney | Original Music Composer |
