 | James McAvoy als Patricia / Dennis / Hedwig / The Beast / Barry / Heinrich / Jade / Ian / Mary Reynolds / Norma / Jalin / Kat / B.T. / Kevin Wendell Crumb / Mr. Pritchard / Felida / Luke / Goddard / Samuel / Polly |
 | Bruce Willis als David Dunn / The Overseer |
 | Samuel L. Jackson als Elijah Price / Mr. Glass |
 | Anya Taylor-Joy als Casey Cooke |
 | Sarah Paulson als Dr. Ellie Staple |
 | Spencer Treat Clark als Joseph Dunn |
 | Charlayne Woodard als Mrs. Price |
 | Luke Kirby als Pierce |
 | Adam David Thompson als Daryl |
 | M. Night Shyamalan als Jai, Security Guard |
 | Shannon Destiny Ryan als Cheerleading Girl |
 | Diana Silvers als Cheerleading Girl |
 | Nina Wisner als Cheerleading Girl |
 | Kyli Zion als Cheerleading Girl |
 | Serge Didenko als Ronald, Powerful Young Man |
 | Russell Posner als T, Skinny Camera Kid |
| Kimberly S. Fairbanks als Assistant Principal |
 | Rosemary Howard als Penelope Crumb |
 | Bryan McElroy als Clarence Crumb |
 | Owen Vitullo als Young Kevin |
| William Turner als Young Elijah |
| Johnny Hiram Jamison als Thirteen Year-Old Elijah (archive footage) |
 | Leslie Stefanson als Woman on Train |
| Marc H. Glick als Train Engineer |
| Brick Mason als Carnival Barker |
 | Bostin Christopher als Comic Book Counter Guy |
 | Ukee Washington als News Anchor |
| Colin Becker als Ten Year-Old David |
 | Brian Anthony Wilson als Security Guard in Car |
 | Tobias Segal als Surveillance Security Guard |
 | Joseph Thuet als Joe, Security Guard |
 | Tatiana St. Phard als Woman Group Member |
 | Tom DiNardo als Homeless Person |
 | Timothy Chivalette als Comic Book Geek |
 | Jack McCafferty als Comic Book Geek |
| Darby Schlosser als Foster Sibling |
| Jordan Coker als Foster Sibling |
 | Emma Hong als Foster Sibling |
| Xaiver Gerald als Foster Sibling |
 | Tim Duquette als Patient Jimmy |
| Nathan Nauroth als Orderly Harrison |
 | Ana Leonard als Hospital Volunteer |
 | Elijah Davis als Maintenance worker (uncredited) |
 | Charles W Harris III als Officer Williams (uncredited) |
 | Jesse Ridgway als College Student (uncredited) |
| M. Night Shyamalan | Director |
| Jason Blum | Producer |
| Chris Trujillo | Production Design |
| Luke Ciarrocchi | Editor |
| Mike Gioulakis | Director of Photography |
| Michael Maddi | Prosthetics Sculptor |
| John Burton West | Production Manager |
| Ashwin Rajan | Producer |
| Ben Bornstein | Prosthetic Makeup Artist |
| Steven Schneider | Executive Producer |
| Diane Dixon | Hair Department Head |
| Marc Bienstock | Producer |
| Douglas Aibel | Casting |
| Jesse Rosenthal | Art Direction |
| Margina Dennis | Makeup Artist |
| West Dylan Thordson | Original Music Composer |
| Kevin Scott Frakes | Executive Producer |
| Olivia Peebles | Set Decoration |
| John Rusk | Co-Producer |
| M. Night Shyamalan | Producer |
| Paco Delgado | Costume Design |
| Michael Maddi | Prosthetic Designer |
| Renaldo Kell | Editor |
| Pamela Peitzman | Makeup Department Head |
| Jason Fyrberg | Sound Mixer |
| William Lance | Set Designer |
| M. Night Shyamalan | Screenplay |
| Sean Garnhart | Sound Designer |
| Dave Kellom | Art Department Coordinator |
| Charles S. Rowe | Script Supervisor |
| Jason Loftus | Casting |
| Ian Seabrook | Underwater Director of Photography |
| Bill Vargo | Video Assist Operator |
| Andrew Joffe | Electrician |
| Ryan 'Sparks' Lynch | Chief Lighting Technician |
| Liza James | Ager/Dyer |
| Staci Hagenbaugh | Location Manager |
| Jessica Kourkounis | Still Photographer |
| Manny Siverio | Stunt Coordinator |
| Diane Heery | Casting |
| Ian S. Takahashi | Underwater Camera |
| Sandi Figueroa | Costumer |
| Aaron Becker | Title Designer |
| Aidan John Miller | Tailor |
| Jon Sibert | Key Grip |
| Rita Squitiere | Costume Supervisor |
| Tim Linden | Property Master |
| Jason Cortazzo | Libra Head Technician |
| Kara Morasco | Tailor |
| Teresa Binder Westby | Assistant Costume Designer |
| Christy Guillermain | Costumer |
| Dann Fink | ADR Voice Casting |
| Askia Won-Ling Jacob | Costumer |
| Chris Clemens | Pilot |
| Susan Jacobs | Music Co-Supervisor |
| Paul Maiello | Construction Coordinator |
| Yusuf Hassan | Script Coordinator |
| Thomas Devine | Electrician |
| Kasha Meyers | Costume Assistant |
| Angeline Zeigler | Set Costumer |
| Everette Webber | Digital Intermediate Editor |
| Kelly Bruce | Compositing Supervisor |
| Katherine Soares | Visual Effects Producer |
| Jonathan Stone | Visual Effects Producer |
| Jared Levin | Visual Effects Coordinator |
| Patrick Edward White | Special Effects Coordinator |
| Kathryn Cates | Assistant Editor |
| Brian Houlihan | Compositing Supervisor |
| Travis Avitabile | Digital Intermediate Producer |
| Kevin Murray | Assistant Editor |
| Travis Reinke | 3D Modeller |
| Arslan Naqvi | Compositing Supervisor |
| Andreia Lucas | Visual Effects Editor |
| Dan Boujoulian | Visual Effects Editor |
| Chris Giuffrida | Colorist |
| Rich Pernice | Visual Effects Editor |
| Ryan Cunningham | Visual Effects Producer |
| Chris Jensen | Digital Intermediate Colorist |
| Bob Peishel | Digital Intermediate Producer |
| Skip Lievsay | Sound Re-Recording Mixer |
| Blu Murray | Editor |
| Emily Austin Griswold | VFX Artist |
| Susan Jacobs | Music Supervisor |
| Gary Barber | Executive Producer |
| Roger Birnbaum | Executive Producer |
| Marc Bienstock | Unit Production Manager |
| John Burton West | Unit Production Manager |
| John Rusk | First Assistant Director |
| Alison C. Rosa | Second Assistant Director |
| Zack Roberts | Stunts |
| Mark Pettograsso | Stunts |
| Ricky Barksdale | Stunts |
| Chris Dyer | Stunts |
| Anthony Hoang | Stunts |
| Jim Ford | Stunts |
| Patrick M. Walsh | Stunts |
| Roberto Gutierrez | Stunts |
| Earl Weathers | Stunts |
| Elvis Valentino Lopez | Stunts |
| Mohammed J. Ali | Stunts |
| Jason Ng | Stunts |
| Rick Kain | Stunts |
| Matthew R. Staley | Stunts |
| James Ortiz | Stunts |
| David Shumbris | Stunts |
| Brian Donahue | Stunts |
| Victor Chan | Stunts |
| Anthony Mecca | Stunts |
| John McEnerney | Stunts |
| Aaron Joshua | Stunts |
| Chris Colombo | Stunts |
| Wendy Gutierrez | Stunts |
| Stephen Mann | Stunts |
| Stuart F. Wilson | Stunts |
| Kenny Wong | Stunts |
| Jeff Ward | Stunts |
| Zoli Dora | Stunts |
| Chazz Menendez | Stunts |
| Christian Dorsey | Stunts |
| Michael Viola | Stunts |
| Christopher Jon Gombos | Stunts |
| Giuseppe Ardizzone | Stunts |
| Bryce Burke | Stunts |
| Peter Wallack | Stunts |
| Kimmy Suzuki | Stunts |
| Chad Knorr | Stunts |
| Dom Catanzarite | Associate Producer |
| Matthew Shapiro | Post Production Supervisor |
| Skip Lievsay | Supervising Sound Editor |
| Kyle Rudolph | "A" Camera Operator |
| Kyle Rudolph | Steadicam Operator |
| Scott Johnson | First Assistant "A" Camera |
| Michael Leonard | First Assistant "B" Camera |
| Leon Sanginiti | Second Assistant "A" Camera |
| James McCann | Second Assistant "B" Camera |
| Sean Galczyk | Camera Loader |
| Kelly Doran | Boom Operator |
| Ye Zhang | Utility Sound |
| William P. Fiedler | Best Boy Electric |
| Ryan Callahan | Best Boy Grip |
| Mark Catania | Dolly Grip |
| Ken McCallum | Dolly Grip |
| Sheridan Braxton | Grip |
| Caswell Cooke | Grip |
| Matthew Hanlon | Grip |
| Shane Sibert | Grip |
| Liza James | Set Costumer |
| Ray Santoleri | Key Makeup Artist |
| Natalie Young | Makeup Artist |
| Janice Innella | Key Hair Stylist |
| Camille Friend | Hairstylist |
| Justine Frank | Art Department Assistant |
| Brick Mason | Storyboard Artist |
| Ray Fisher | Leadman |
| Samantha Higgins | Set Dresser |
| Benjamin J. Woodward | Assistant Property Master |
| Jay Rogers | Production Coordinator |
| Trish McMiniment | Assistant Production Coordinator |
| Janelle Coleman | Production Secretary |
| Blair Howley | Second Second Assistant Director |
| Chris Gormley | Assistant Location Manager |
| John Galloway | Assistant Location Manager |
| Stephanie Holbrook | Casting Associate |
| Henry Russell Bergstein | Casting Associate |
| Deborah Maxwell Dion | Casting Associate |
| Ryan Drake | Casting Assistant |
| Sean Garnhart | Sound Re-Recording Mixer |
| Lee Salevan | Sound Effects Editor |
| Igor Nikolic | Foley Editor |
| Michael Feuser | Dialogue Editor |
| Brian Bowles | Dialogue Editor |
| Jac Rubenstein | Dialogue Editor |
| Lidia Tamplenizza | ADR Editor |
| Rachel Wardell | Assistant Sound Editor |
| Matthew Kay | Foley Mixer |
| Jay Peck | Foley Artist |
| Jackie Mulhearn | Assistant Music Supervisor |
| Suzanna Perić | Music Editor |
| Jeanene Fiedler | Craft Service |
| Kyli Zion | Stunts |
