 | John Goodman als Fred Flintstone |
 | Elizabeth Perkins als Wilma Flintstone |
 | Rick Moranis als Barney Rubble |
 | Rosie O'Donnell als Betty Rubble |
 | Kyle MacLachlan als Cliff Vandercave |
 | Halle Berry als Sharron Stone |
 | Elizabeth Taylor als Pearl Slaghoople |
 | Dann Florek als Mr. Slate |
 | Richard Moll als Hoagie |
 | Irwin Keyes als Joe Rockhead |
 | Jonathan Winters als Gobo The Grizzled Man |
 | Harvey Korman als Ali / Dicabird / Blossom's Adopted Doll Son Ali |
 | Lainey Silver als Pebbles |
 | Melanie Silver als Pebbles |
 | Hlynur Sigurðsson als Bamm-Bamm |
 | Marinó Sigurðsson als Bamm-Bamm |
 | Sheryl Lee Ralph als Mrs. Pyrite |
 | Jean Vander Pyl als Mrs. Feldspar |
 | Janice Kent als Stewardess |
 | Jack O'Halloran als Yeti |
 | Becky Thyre als Roxanne |
 | Rod McCary als Store Manager |
 | Kate Pierson als BC-52's |
 | Fred Schneider als BC-52's |
 | Keith Strickland als BC-52's |
 | Jim Doughan als Maitre d' |
 | Laraine Newman als Susan Rock |
 | Jay Leno als Bedrock's Most Wanted Host |
 | Alan Blumenfeld als Fred Look-A-Like |
| Messiri Freeman als Miss Stone Look-A-Like |
| Alex Zimmerman als Accuser |
 | Sam Raimi als Cliff Look-A-Like |
| Tommy Terrell als Accuser |
| Andy Steinfeld als Aerobics Instructor |
| Bradford Bryson als Foreman |
| Tabbie Brown als Accuser |
 | Dean Cundey als Technician |
| Lita Stevens als Woman at Chevrox |
 | Joseph Barbera als Man in Mersandes |
 | William Hanna als Executive in Boardroom |
 | Mel Blanc als Dino (voice) (archive sound) |
 | Sam the Orangutan als Neighbor |
| Nancy Nayor | Casting |
| Richard Olso | Sound Director |
| Tom S. Parker | Screenplay |
| Rosanna Norton | Costume Design |
| William Hanna | Executive Producer |
| David Kirschner | Executive Producer |
| Bill Getty | Sound Director |
| Marty Paich | Original Music Composer |
| Steven E. de Souza | Screenplay |
| Bruce Cohen | Producer |
| Dean Cundey | Director of Photography |
| Christopher Burian-Mohr | Art Direction |
| Jim Jennewein | Screenplay |
| Kent Beyda | Editor |
| William Sandell | Production Design |
| William James Teegarden | Art Direction |
| Ted Nichols | Original Music Composer |
| Rosemary Brandenburg | Set Decoration |
| Nancy Patton | Art Direction |
| Joseph Barbera | Executive Producer |
| Kathleen Kennedy | Executive Producer |
| Steven Spielberg | Executive Producer |
| Brian Levant | Director |
| Gerald R. Molen | Executive Producer |
| Colin Wilson | Producer |
| Michelle Fandetti | Post Production Supervisor |
| Eloy Lobato | Production Design |
| Paul Deason | Unit Production Manager |
| Susan Pickett | Second Second Assistant Director |
| Nancy Sandberg | Production Manager |
| Elizabeth Campbell | Trainee Production Coordinator |
| Allen Tinkley | Location Manager |
| Marty P. Ewing | First Assistant Director |
| Gary Hymes | Second Unit Director |
| Denny Caira | Transportation Coordinator |
| Annette Haywood-Carter | Script Supervisor |
| Dana J. Kuznetzkoff | Second Assistant Director |
| William Plant | Production Supervisor |
| Curt Schulkey | Supervising ADR Editor |
| Donald Sylvester | ADR Editor |
| Jim Passon | Color Timer |
| Gary Burritt | Negative Cutter |
| Jay Johnson | Title Designer |
| Ronald Batzdorff | Still Photographer |
| Caroline Quinn | Art Department Coordinator |
| Raymond Stella | Camera Operator |
| Michael Lantieri | Special Effects Supervisor |
| Cynthia Barr | Key Makeup Artist |
| Mary Burton | Makeup Artist |
| Christina Smith | Makeup Artist |
| Larry Waggoner | Key Hair Stylist |
| Linle White | Hairstylist |
| William Howard | Hairstylist |
| Michael Orefice | Chief Lighting Technician |
| Ron Cardarelli | Key Grip |
| Sid Lucero | Best Boy Grip |
| Dave Wachtman | Dolly Grip |
| Chris L. Spellman | Leadman |
| Cal DiValerio | Construction Coordinator |
| Bruce DiValerio | Construction Foreman |
| Gary Hymes | Stunt Coordinator |
| Brian Smrz | Stunts |
| Jeff Jensen | Stunts |
| Pat Romano | Stunts |
| Kim Robert Koscki | Stunts |
| Alex Gaona | Stunts |
| Mark A. Mangini | Supervising Sound Editor |
| Ronald Fischer | Stand In |
| Adam Shankman | Choreographer |
| Rosine 'Ace' Hatem | Stunt Double |
| David Newman | Original Music Composer |
