 | Stephen Hawking als Self |
 | Isobel Hawking als Self - Stephen Hawking's Mother |
| Janet Humphrey als Self - Stephen Hawking's Aunt |
| Mary Hawking als Self - Stephen Hawking's Sister |
| Basil King als Self - Childhood Friend |
| Derek Powney als Self - Oxford Classmate |
| Norman Dix |
| Robert Berman als Self - Stephen Hawking's Tutor |
| Gordon Berry |
 | Roger Penrose |
| Dennis Sciama |
| John Archibald Wheeler |
| Brandon Carter |
| John R. Taylor |
 | Kip Thorne |
| Don Page |
| Christopher Isham |
| Brian Whitt |
| Raymond Laflamme |
| John Bailey | Director of Photography |
| Errol Morris | Director |
| David Hickman | Producer |
| Stephen Hawking | Author |
| Steven Spielberg | Executive Producer |
| Philip Glass | Original Music Composer |
| Stefan Czapsky | Director of Photography |
| Brad Fuller | Editor |
| Ted Bafaloukos | Production Design |
| David Lee | Art Direction |
| Kathleen Kennedy | Executive Producer |
| Gordon Freedman | Executive Producer |
| Colin Ewing | Executive Producer |
| Kurt Munkasci | Music Producer |
| Randy Thom | Sound Effects |
| Lisa Schecter | Associate Editor |
| Julian Rodd | Associate Editor |
| Charlie Silver | Consulting Editor |
| William A. Anderson | Additional Editing |
| Eliza Johnston | Assistant Editor |
| Mary Skinner | Intern |
| Ira Spiegel | Sound Editor |
| Eliza Paley | Sound Editor |
| Ed Barteski | Assistant Sound Editor |
| Julie Lindner | Assistant Sound Editor |
| Suki Buchman | Music Editor |
| Randy Thom | Sound Re-Recording Mixer |
| Bob Edwards | Sound Re-Recording Mixer |
| Michael Riesman | Conductor |
| Rory Johnston | Executive Producer |
| Angela Dryden | Sound Engineer |
| Scott Hollingsworth | Assistant Sound Engineer |
| Dante Desole | Assistant Sound Engineer |
| Nick Heckstall-Smith | First Assistant Director |
| Philippe Carr-Forster | Camera Operator |
| Steve Parker | Focus Puller |
| John Foster | Clapper Loader |
| Bruce White | Sound Mixer |
| Jenny Dyer | Property Buyer |
| Jenny Dyer | Set Dresser |
| Christine A. Sacani | Production Coordinator |
| Peter Butler | Grip |
| Bill Geddes | Grip |
| John Payne | Grip |
| Tony Sankey | Grip |
| Paul Hedges | Property Master |
| Mark Hedges | Props |
| Terry Dunne | Props |
| Richard Maris | Props |
| Rebekah Ingalls | Props |
| Kevin Bryan | Electrician |
| Steve Kitchen | Electrician |
| Bob Olley | Electrician |
| Peter Toley | Electrician |
| George Webb | Electrician |
| Suzie Zamit | Makeup Artist |
| Alan Chesters | Construction Manager |
| Bob Cox | Construction Manager |
| Jim Foran | Carpenter |
| John Bastin | Carpenter |
| Ned Kelly | Carpenter |
| Michael Webb | Carpenter |
| Michael Hersey | Painter |
| Lee Robert Betts | Painter |
| Pat Lynch | Painter |
| Alan Pearson | Painter |
| Andrew MacBean | Thanks |
| Gene Stone | Thanks |
