 | Scarlett Johansson als Kathy Caldwell |
 | Eva Mendes als Matilda |
 | Judge Reinhold als Richard Caldwell |
 | Alex D. Linz als Freud |
 | Romy Walthall als Dee Dee Caldwell |
 | Renée Victor als Grandma Berta |
 | Nick Fuoco als George Caldwell |
 | Marco Rodríguez als Edwardo |
| Eduardo Antonio Garcia als Luis |
 | Paul Renteria als Border Guard |
| Cambria Gonzalez als Mercedes |
| Nicole Zarate als Annie |
| Siri Baruc als Tourist Girl |
| Charlie Combes als Tourist Dad |
| Dee Ann Johnston als Tourist Mom |
| Rob Johnston als Taxi Driver |
 | Dee Bradley Baker als Pig George (voice) |
| Erik Fleming | Director |
| Matthew Flynn | Writer |
| Donald Paul Pemrick | Casting |
| Dean E. Fronk | Casting |
| Dan Reardon | Producer |
| Steven Robiner | Visual Effects Supervisor |
| Gilles Arondeau | Production Design |
| Michael Giacchino | Original Music Composer |
| Michael Stone | Director of Photography |
| Scott Conrad | Editor |
| Adam Novak | Associate Producer |
| Stephen Eckelberry | Associate Producer |
| Robert E. Baruc | Executive Producer |
| Deborah Thompson Duda | Co-Producer |
| Philip Botana | Producer |
| Scott Vandiver | Producer |
| Jim Hewitt | Art Direction |
| Patti MacIsaac | Set Decoration |
| Julie Merrill | Costume Supervisor |
| April Hutchinson | Key Makeup Artist |
| April Hutchinson | Key Hair Stylist |
| Julianne Kaye | Key Makeup Artist |
| Julianne Kaye | Key Hair Stylist |
| Brandon Walker | Supervising Sound Editor |
| Michael Olman | Sound Re-Recording Mixer |
| Liz Sroka | Sound Re-Recording Mixer |
