 | John Wayne als Robert Marmaduke Sangster Hightower |
 | Pedro Armendáriz als Pedro 'Pete' Roca Fuerte |
 | Harry Carey, Jr. als William Kearney ('The Abilene Kid') |
 | Ward Bond als Perley 'Buck' Sweet |
 | Mae Marsh als Mrs. Perley Sweet |
 | Mildred Natwick als The Mother |
 | Jane Darwell als Miss Florie |
 | Guy Kibbee als Judge |
 | Dorothy Ford als Ruby Latham |
 | Ben Johnson als Posse man #1 |
 | Charles Halton als Oliver Latham |
 | Hank Worden als Deputy Curly |
 | Jack Pennick als Luke |
 | Fred Libby als Deputy |
 | Michael Dugan als Posse Man #2 |
| Don Summers als Posse Man #3 |
 | Gertrude Astor als Saloon Girl (uncredited) |
 | Richard Hageman als Saloon Pianist (uncredited) |
| Nora Bush als Townswoman (uncredited) |
 | Eva Novak als Townswoman (uncredited) |
| Charles Soldani als Townsman (uncredited) |
 | Ruth Clifford als Woman in Bar (uncredited) |
 | Jack Curtis als Bartender (uncredited) |
 | Harry Tenbrook als Bartender (uncredited) |
 | Tex Driscoll als Barfly (uncredited) |
 | Jack Kenny als Barfly (uncredited) |
 | Jack Mower als Barfly (uncredited) |
 | Francis Ford als Drunk (uncredited) |
 | Cliff Lyons als Guard at Mojave Tanks (uncredited) |
| Amelia Yelda als Robert William Pedro Hightower (the Baby) (uncredited) |
| James Basevi | Art Direction |
| Merian C. Cooper | Producer |
| Merian C. Cooper | Presenter |
| Ben Johnson | Stunts |
| John Ford | Director |
| John Ford | Producer |
| John Ford | Presenter |
| Lowell J. Farrell | Production Manager |
| Eddie Fitzgerald | Camera Operator |
| Winton C. Hoch | Director of Photography |
| Terry Wilson | Stunts |
| Joseph Kish | Set Decoration |
| Laurence Stallings | Screenplay |
| Harry Carey | In Memory Of |
| Frank S. Nugent | Screenplay |
| Jack Murray | Editor |
| Frank McGrath | Stunt Double |
| Michael Dugan | Stunts |
| Robert Nathan | Writer |
| Richard Hageman | Original Music Composer |
| Peter B. Kyne | Story |
| Don L. Cash | Makeup Artist |
| Lucien Cailliet | Conductor |
| Lucien Cailliet | Music Arranger |
| Cliff Lyons | Stunts |
| Jack Williams | Stunts |
| Charles P. Boyle | Second Unit Director of Photography |
| Stan Jones | Technical Advisor |
| Sid Davis | Stand In |
| Edward O'Fearna | Assistant Director |
| Bryan 'Slim' Hightower | Stunts |
| D. Pat Kelley | Sound Effects |
| Wingate Smith | Assistant Director |
| Harvey Gould | Camera Operator |
| Natalie Kalmus | Colorist |
| Ann Peck | Wardrobe Master |
| Jack Caffee | Special Effects |
| Joseph I. Kane | Sound |
| Anna Malin | Hairstylist |
| Frank Wesselhoff | Painter |
| Alexander Kahle | Still Photographer |
| Jack Colconda | Property Master |
| Frank W. Moran | Sound |
| D.R.O. Hatswell | Costume Consultant |
| Tommy Griffin | Grip |
| Michael Meyers | Wardrobe Master |
| Meta Stern | Script Supervisor |
| Pat kelly | Script Supervisor |
