 | Samuel L. Jackson als Andrew Sterling |
 | Nicolas Cage als Amos Odell |
 | Michael Lerner als Phil Gillman |
 | Margaret Colin als Judy Gillman |
 | Dabney Coleman als Chief of Police Cecil Tolliver |
 | Brad Dourif als Officer Donnie Donaldson |
 | Chelcie Ross als Deputy Earl |
 | Jordan Lund als Deputy Riley |
 | I.M. Hobson als Waldo Lake |
 | Jeff Blumenkrantz als Ernie |
 | Todd Weeks als Stan |
 | Jodi Long als Wendy Wong |
 | Michael Burgess als Black Reporter |
| Leonor Anthony als Hispanic Reporter |
| Walter Raymond als Anchorman |
 | Giancarlo Esposito als The Reverend Fenton Brunch |
 | Loretta Devine als Ula |
 | Bob Balaban als Dr. R. A. (Roy) Fink |
 | Ron Taylor als Sherman |
 | Aimee Graham als Stacy |
| Ernie Garrett als State Police Captain |
 | Tracey Walter als Bloodhound Bob |
 | Allison Mackie als Anchorwoman |
| Eric Paisley als Mainland Gatekeeper |
 | Kim Staunton als Mrs. Andrew Sterling |
| E. Max Frye | Writer |
| E. Max Frye | Director |
| Jane Kurson | Editor |
| Jack Cornish | Construction Foreman |
| Patricia Norris | Production Design |
| Gary Goetzman | Producer |
| Glenn Randall Jr. | Stunt Coordinator |
| Elizabeth Ziegler | Steadicam Operator |
| Carlton Kaller | Music Editor |
| Amy Stofsky | Costume Supervisor |
| Gordon Antell | First Assistant Editor |
| Nina K. Noble | Second Assistant Director |
| Deborah Winship | Leadman |
| Marcy G. Kaplan | Production Supervisor |
| Carl Boles | Gaffer |
| Jeff 'Moose' Howery | Dolly Grip |
| Leslie Morales | Set Decoration |
| Denny DiAddezzio | Assistant Property Master |
| Jim Bridges | Still Photographer |
| Robert Beck | Property Master |
| John S. Lyons | Casting |
| Jack Cummins | Production Manager |
| Patricia Norris | Costume Design |
| Shawn McKay | Hairstylist |
| Isom Ison III | Construction Foreman |
| Tom Harjo | Key Grip |
| William G. Davis | Assistant Art Director |
| Eddie Collins | Camera Operator |
| Sioux Richards | Script Supervisor |
| Walt Lloyd | Director of Photography |
| John Pritchett | Sound Mixer |
| Richard Gibbs | Original Music Composer |
| Jack Cummins | Co-Producer |
| Marshall Persinger | Co-Producer |
| Tom Jones Jr. | Construction Coordinator |
| Jean Ann Black | Makeup Artist |
| Henry J. Bronchtein | First Assistant Director |
| Ken Hudson | Camera Loader |
| Jonathan Demme | Executive Producer |
| Tony Brubaker | Stunts |
