 | Meryl Streep als Alice Hughes |
 | Lucas Hedges als Tyler Hughes |
 | Gemma Chan als Karen |
 | Dianne Wiest als Susan |
 | Candice Bergen als Roberta |
 | Daniel Algrant als Kelvin Krantz |
 | John Douglas Thompson als Dr. Mitchell |
 | Christopher Fitzgerald als Eddie |
 | Mary Catherine Garrison als Customer |
 | Elna Baker als Clovis |
 | Samia Finnerty als Samia |
 | Fred Hechinger als Fred |
 | David Siegel als Karen's Boss |
 | Mike Doyle als Murray Dix |
 | David Shepherd als QM2 Hotel Manager |
| Stephanie Phippen als Check-in Agent |
| Dominic Crisonino als Terminal Guide |
| Barbara Rickard als Autograph Seeker |
| Haydn Rickard als Autograph Seeker |
 | Hannah James als Salon Receptionist |
| Andrea Kaiser als QM2 Officer |
| Al Gwilt als Vernon |
 | Saskia Larsen als Mika (uncredited) |
| Pete Meads als Hotel Guest (uncredited) |
| Steven Soderbergh | Director |
| Deborah Eisenberg | Screenplay |
| Gregory Jacobs | Producer |
| Ken Meyer | Executive Producer |
| Joseph Malloch | Executive Producer |
| Steven Soderbergh | Editor |
| Ellen Mirojnick | Costume Design |
| Joseph Malloch | Unit Production Manager |
| David Page | Set Costumer |
| Thomas Newman | Original Music Composer |
| Steven Soderbergh | Director of Photography |
| Corey Bayes | Co-Producer |
| Carmen Cuba | Casting |
| Andy Eklund | Art Direction |
| Amie English | Art Direction |
| Donna Marie Fischetto | Key Hair Stylist |
| J. Roy Helland | Makeup Artist |
| J. Roy Helland | Key Hair Stylist |
| Michael Jortner | Property Master |
| Fernando Torres Idrovo | Visual Effects Supervisor |
| Shawn Allen | Boom Operator |
| Josh Berger | Sound Re-Recording Mixer |
| Leslie Bloome | Foley Artist |
| Alex Carpenter | Foley Editor |
| Ryan Collison | Foley Mixer |
| Ian Cymore | Sound Effects Editor |
| Russell Edwards | Production Sound Mixer |
| Grant Elder | Sound Effects Editor |
| Joanna Fang | Foley Artist |
| Laura Heinzinger | Foley Editor |
| Thomas W. Jordan | Boom Operator |
| Kevin Peters | Dialogue Editor |
| Nick Seaman | Foley Editor |
| Dennis Towns | Sound Mixer |
| Tim Wong | Boom Operator |
| Mark Lee Cobb | Camera Operator |
| Kate Louise Eccarius | Focus Puller |
| Derek Gross | Gaffer |
| Gary Jay | Camera Operator |
| Jeff Makarauskas | First Assistant Camera |
| James Malamatinas | Clapper Loader |
| Dean Martinez | First Assistant Camera |
| Troy Sola | First Assistant Camera |
| Melissa Braun | Extras Casting |
| Sabrina Calley | Key Costumer |
| Corey Bayes | Associate Editor |
| Gil Litver | Digital Intermediate Assistant |
| Mae Sussman | First Assistant Editor |
| John Beasley | Orchestrator |
| John Beasley | Conductor |
| Peter Erskine | Musician |
| Jeff Gartenbaum | Score Engineer |
| Shinnosuke Miyazawa | Music Editor |
| Erin Michael Rettig | Score Engineer |
| Thomas Vicari | Scoring Mixer |
| Joseph Featherstone | Transportation Captain |
| Ann Caprio | First Assistant Accountant |
| David Koll | Production Secretary |
| Greg Loftus | Production Assistant |
| Amanda Lynch | Production Coordinator |
| Charlotte Rose Manning | Production Assistant |
| Emily Suber | Title Designer |
| Keri Weisblum | Post Production Accountant |
| Kirk Harris | Driver |
| Gregory Jacobs | First Assistant Director |
| Jody Spilkoman | Second Assistant Director |
| Larry Blake | Thanks |
| Nat Jencks | Colorist |
| Tahira Ali | VFX Artist |
| Sean Findley | Visual Effects Producer |
| Jonathan Jelkin | VFX Artist |
| Stephen Siemens | VFX Artist |
| Nicolaus Waetjen | VFX Artist |
| Dann Fink | ADR Voice Casting |
| Grant Wilfley | Extras Casting |
| Bruce Winant | ADR Voice Casting |
| Alex Hartley | Data Wrangler |
| Ethan Leight | Digital Intermediate Producer |
| Tom Younghans | Digital Intermediate Assistant |
| Abigail Atkinson | Production Manager |
| Leslie J. Converse | Post Production Supervisor |
| Jo Coombes | Head of Production |
| Callum Crozier | Unit Manager |
| Sara Neuffer | Second Second Assistant Director |
| Rosie Owen | Third Assistant Director |
| Joshua Weinstein | Thanks |
| Ernest Karpeles | Location Scout |
| Ernie Karpeles | Location Scout |
| Amy Morement | Location Manager |
| Hyo Park | Location Manager |
| Dan Schroeder | Location Assistant |
| Jeremy Stern | Location Manager |
| Robert T. Striem | Location Manager |
| Carol A. Compton | Script Researcher |
