 | Mitchel Musso als Douglas 'DJ' Hartner (voice) |
 | Sam Lerner als Chowder (voice) |
 | Spencer Locke als Jenny Bennett (voice) |
 | Steve Buscemi als Nebbercracker (voice) |
 | Maggie Gyllenhaal als Zee (voice) |
 | Kevin James als Officer Landers (voice) |
 | Nick Cannon als Officer Lister (voice) |
 | Jon Heder als Reginald 'Skull' Skulinski (voice) |
 | Jason Lee als Bones (voice) |
 | Catherine O'Hara als Mom (voice) |
 | Fred Willard als Dad (voice) |
 | Kathleen Turner als Constance (voice) |
 | Ryan Whitney Newman als Little Girl (voice) |
 | Woody Schultz als Paramedic #1 (voice) |
| Ian McConnel als Paramedic #2 (voice) |
 | Erik Walker als Bully #1 (voice) |
 | Matthew Fahey als Bully #2 (voice) |
| Gil Kenan | Director |
| Dan Harmon | Screenplay |
| Rob Schrab | Screenplay |
| Pamela Pettler | Screenplay |
| Jack Rapke | Producer |
| Michael Ferris | Camera Operator |
| Justin Hammond | Lighting Artist |
| Harald Kraut | Layout |
| Josh LaBrot | Layout |
| Ruth Myers | Costume Design |
| Michèle Burke | Makeup Artist |
| Tyler Ely | Hairstylist |
| Roxane Griffin | Hair Setup |
| Mark Landon | Makeup Artist |
| Tegan Taylor | Makeup Artist |
| Jason Clark | Executive Producer |
| Heather Kelton | Associate Producer |
| Bennett Schneir | Associate Producer |
| Steven Spielberg | Executive Producer |
| Steve Starkey | Producer |
| Peter M. Tobyansen | Line Producer |
| Robert Zemeckis | Executive Producer |
| Xavier Grobet | Director of Photography |
| Fabienne Rawley | Editor |
| Adam P. Scott | Editor |
| Scot Boland | Casting |
| Victoria Burrows | Casting |
| Demian Gordon | Motion Capture Artist |
| Michael Lantieri | Special Effects |
| Vincent Palermo | Motion Capture Artist |
| Darin Velarde | Animation |
| James M. Halty | Stunts |
| Bob MacDougall | Stunts |
| Susan Purkhiser | Stunts |
| Pat Romano | Stunt Coordinator |
| Misty Rosas | Stunts |
| Jamaal Bradley | Animation |
| Stéphane Couture | Animation |
| Stephen Enticott | Animation |
| Luca Erbetta | Animation |
| Mark R.R. Farquhar | Animation |
| Allen Foster | Layout |
| Robert Fox | Animation |
| Kevin Freeman | Animation |
| Angie Glocka | Animation |
| Bill Haller | Animation |
| Dan Heder | Animation |
| Seth Hippen | Animation |
| T. Daniel Hofstedt | Animation Supervisor |
| Paul Jessel | Animation |
| Alice V. Kaiserian | Animation |
| Sebastian Kapijimpanga | Animation |
| Keith Kellogg | Animation |
| Mike Laubach | Animation Manager |
| Eric Lees | Animation |
| Jeff Lin | Animation |
| Christopher D. Lindsay | Animation |
| Jason McDade | Layout |
| Sandra Ryan-Moran | Animation |
| Denis Samoilov | Animation |
| Jesse Sugarman | Animation |
| Marc Vulcano | Animation |
| Kevin Wang | Technical Supervisor |
| Danny Wawrzaszek | Animation |
| John Wong | Animation |
| William R. Wright | Animation |
| Anthony Almaraz | Costume Supervisor |
| Sandra Bojin-Sedlik | Costume Design |
| Laura Neeff | Costume Design |
| David Howard | Camera Operator |
| Roger C. Johnson | Video Assist Operator |
| Jesse Kaplan | Camera Operator |
| Marc Lulkin | Camera Operator |
| Mariana Sánchez de Antuñano | Camera Operator |
| Chris Wagganer | Camera Operator |
| Kirby Washington | Camera Operator |
| Dan Abrams | Visual Development |
| Elaine C. Andrianos | Visual Effects Editor |
| Michael Alkan | Lighting Technician |
| Matthew Adams | Lighting Technician |
| Mayumi Arakaki | Visual Effects |
| Todd Boyce | Visual Effects |
| John Dillon | Art Department Manager |
| Jay Jackson | Animation |
| Chris Appelhans | Conceptual Design |
| Ed Verreaux | Production Design |
| Norman Newberry | Art Direction |
| Greg Papalia | Art Direction |
| Douglas Pipes | Original Music Composer |
| Kate J. Sullivan | Set Decoration |
| Scott Holmes | Animation |
| Trinh Tran | Post Production Assistant |
| Marc Gabbana | Concept Artist |
| Armen Ksajikian | Musician |
| Randy Thom | Sound Designer |
| Randy Thom | Supervising Sound Editor |
| Randy Thom | Sound Re-Recording Mixer |
| Dennis Leonard | Supervising Sound Editor |
| Gary Rizzo | Sound Re-Recording Mixer |
| Jason Corgan Brown | Researcher |
