 | Joel McHale als Johnny Cage (voice) |
 | Jennifer Grey als Jennifer Grey / Sareena (voice) |
 | Dusan Brown als Chuck Golden (voice) |
 | Grey DeLisle als Kia / Little Boy / Old Lady (voice) |
 | Robin Atkin Downes als Shinnok (voice) |
 | Zehra Fazal als Jataaka (voice) |
 | Gilbert Gottfried als David Doubldy (voice) |
 | Kelly Hu als Ashrah (voice) |
 | Matthew Yang King als Concierge / Costumed Hero (voice) |
 | Phil LaMarr als Brian Van Jones (voice) |
 | Matthew Mercer als Director / Bully (voice) |
 | Dave B. Mitchell als Raiden / Bus Driver (voice) |
 | Armen Taylor als Master Boyd / Mugger (voice) |
 | Kyle Wyatt als Mob Leader (voice) |
| Ethan Spaulding | Director |
| Rick Morales | Supervising Producer |
| Jeremy Adams | Writer |
| Sam Register | Executive Producer |
| Ed Boon | Executive Producer |
| Ed Boon | Video Game |
| John Tobias | Video Game |
| James Krieg | Producer |
| Alyessa Ornelas | Line Producer |
| John Jennings Boyd | Original Music Composer |
| Eric V. Hachikian | Original Music Composer |
| Craig Paulsen | Editor |
| Wes Gleason | Casting |
| Kaiti Williamson | Production Manager |
| Marco Amendola | Assistant Production Manager |
| Helena Crist | Assistant Production Manager |
| Keiji Kishi | Assistant Production Manager |
| Taylor Thornton | Assistant Production Manager |
| Todd Gibbs | Art Direction |
| Steven Choi | Character Designer |
| Michelle Drennan | Character Designer |
| Walter Gatus | Character Designer |
| Dinah Kalaha | Character Designer |
| Beth Lewis | Character Designer |
| Zak Plucinski | Character Designer |
| Austin Reinkens | Character Designer |
| Alexander Wilson | Character Designer |
| Cary Lockwood | Prop Designer |
| Damon Moran | Prop Designer |
| Norm Ryang | Prop Designer |
| Daby Zainab Faidhi | Background Designer |
| Brandon Hahn | Background Designer |
| Gregery Miller | Background Designer |
| Kathryn Rose | Background Designer |
| Jonard Soriano | Background Designer |
| Esther Wu | Background Designer |
| Esther Zhao | Background Designer |
| Anna Hemsworth | Other |
| Mike Inman | Other |
| Terri Ogwulumba | Other |
| Timothy Szabo | Other |
| Daniel Elson | Color Designer |
| James Peters | Color Designer |
| Maribel Pozos | Color Designer |
| Tim Maltby | Storyboard Artist |
| Lila Martinez | Storyboard Artist |
| David Maximo | Storyboard Artist |
| Erwin Osias | Storyboard Artist |
| Jordan Raskin | Storyboard Artist |
| Joe Giampapa | Production Supervisor |
| Drew Ng | Production Supervisor |
| Rodrigo Perez-Castro | Production Supervisor |
| Rebecca Swift | Production Supervisor |
| Steven E. Gordon | Storyboard Artist |
| Florent Lagrange | Storyboard Artist |
| Terry Michaud | Storyboard Artist |
| James Nguyen | Storyboard Artist |
| Jerry Wang | Storyboard Artist |
| Ami Goff | Animation |
| Christopher Graybill | Animation |
| Timothy N. Ryan | Animation |
| Matthew Girardi | Art Direction |
| Brenna Kraus | Graphic Designer |
| Brenna Kraus | Title Designer |
| Emily Kieber | Graphic Designer |
| Emily Kieber | Title Designer |
| Adrienne Steinbaum | Graphic Designer |
| Adrienne Steinbaum | Title Designer |
| Seo Jung-ha | Animation Director |
| Je-Ha Yu | Animation Director |
| Kim Gi June | Layout Supervisor |
| Lee Byeong-seok | Layout Supervisor |
| Byeong-Cheong Shin | Key Animation |
| Yang Sun A | Color Designer |
| Kang Hei Chul | Production Supervisor |
| Greg Emerson | Other |
| Kip Brown | Post Producer |
| Rebecca Sands Coutts | Post-Production Manager |
| Marissa Llano | Post-Production Manager |
| Lisa Hallbauer | Other |
| Emily Dillard | Assistant Production Manager |
| Kenzie Bates | Assistant Production Manager |
| Charlie Carpenter | Assistant Production Manager |
| Jeff O. Collins | Other |
| Wilson Martinez | Other |
| Mark A. Keatts | Supervising Dialogue Editor |
| Mark A. Keatts | ADR Editor |
| David M. Cowan | Dialogue Editor |
| David M. Cowan | ADR Editor |
| Kelly Ann Foley | Dialogue Editor |
| Kelly Ann Foley | ADR Editor |
| Patrick J. Foley | Dialogue Editor |
| Patrick J. Foley | ADR Editor |
| Michael Garcia | Dialogue Editor |
| Michael Garcia | ADR Editor |
| John Reynolds | Dialogue Editor |
| John Reynolds | ADR Editor |
| Fred Salinas | Dialogue Editor |
| Fred Salinas | ADR Editor |
| Milton Adamou | Online Editor |
| Harrison T. Barth | Assistant Editor |
| Michele Beeson | Assistant Editor |
| Gabriel Gianola | Assistant Editor |
| Abigail Overstreet | Production Manager |
| Karina Benesh | Associate Producer |
| Cher Bentley | Other |
| Jeff Deckman | Other |
| Eileen Goldstein | Other |
| Tamara Miles | Other |
| Niko Sumcad | Other |
| Kira Tirimacco | Other |
| Agnes Kim | Casting |
| Maria Millage | Casting |
| Sarah Noonan | Casting |
| Alden Osborne | Casting |
| Morgan Rudner | Casting |
| Liz Carroll | Administration |
| Chaz Murphy | Production Accountant |
| Athena Wingate | Production Accountant |
| Leslie Chinchilla | Legal Services |
| Raymond Gonzalez | Legal Services |
| Denise Martinez | Legal Services |
| Shannon Muir | Legal Services |
| Iman Wilson | Legal Services |
| Lindsey Gui | Other |
| Bobbie Page | Production Supervisor |
| Liz Marshall | Production Supervisor |
| Ed Adams | Production Manager |
| Peter Girardi | Executive In Charge Of Production |
| Gilbert Gottfried | In Memory Of |
