 | Nia Vardalos als Toula Portokalos-Miller |
 | John Corbett als Ian Miller |
 | Elena Kampouris als Paris Miller |
 | Lainie Kazan als Maria Portokalos |
 | Andrea Martin als Aunt Voula |
 | Maria Vacratsis als Aunt Freida |
 | Louis Mandylor als Nick Portokalos |
 | Joey Fatone als Angelo Portokalos |
 | Gia Carides als Nikki Portokalos |
 | Elias Kacavas als Aristotle |
 | Stephanie Nur als Qamar |
 | Melina Kotselou als Victory |
 | Alexis Georgoulis als Peter |
 | Giannis Vasilottos als Christos |
 | Anthi Andreopoulou als Alexandra |
| Spyros Kasfiks als Thanasis |
| Menelaos Ntaflos als Dimos |
 | Ektoras Kaloudis als George |
| Dimosthenis Filippas als Monk |
 | Stavroula Logothettis als Athena |
| Peter Tharos als Yianni |
 | Gerry Mendicino als Uncle Taki |
 | Jeanie Calleja als Ilaria |
 | Kathryn Greenwood als Marge |
 | Jayne Eastwood als Mrs. White |
 | Kathryn Haggis als Marianthi |
| Chrissy Paraskevopoulos als Jennie |
 | Tannis Burnett als Edie |
| Nikolas Papadomihelakis als Airline Rep O'Hare |
 | Jerome Kaluta als Flight Attendant |
 | Daphne Alexander als Flight Attendant |
| Nia Vardalos | Director |
| Grant Armstrong | Production Design |
| Matthew Kerly | Supervising Art Director |
| Apostolos Polyhroniadis | Key Scenic Artist |
| Pete Blaxill | Second Assistant Sound |
| Nikos Drakos | Boom Operator |
| Kian McClure | First Assistant Sound Editor |
| Pete Blaxill | Playback Coordinator |
| Colin Nicolson | Production Sound Mixer |
| Fabrizio Sciarra | Camera Operator |
| Fabrizio Sciarra | Steadicam Operator |
| Panos Tsigas | Camera Operator |
| Spencer Lammy | Principal Costumer |
| Aria Harrison | Script Supervisor |
| Cassandra Barbour | Clearances Coordinator |
| Adam R. Mehr | Legal Services |
| Spencer Lammy | Key Costumer |
| Jenna Barnes | Production Controller |
| Nia Vardalos | Writer |
| Paul Brooks | Executive Producer |
| Michael P. Flannigan | Executive Producer |
| Scott Niemeyer | Executive Producer |
| Rita Wilson | Producer |
| Gary Goetzman | Producer |
| Tom Hanks | Producer |
| Barry Peterson | Director of Photography |
| Herbert Rawlinson | Dialogue Editor |
| Deva Anderson | Music Supervisor |
| Alexios Koukias-Pantelis | Music Coordinator |
| Michael Constantine | In Memory Of |
| Nia Vardalos | Executive Producer |
| Annette Davey | Editor |
| Craig Herring | Editor |
| Stephanie Economou | Original Music Composer |
| Dafni Kalogianni | Art Direction |
| Michael Standish | Set Decoration |
| Timothy A. Wonsik | Costume Design |
| Georgia Apalodima | Makeup Artist |
| Kyriaky Melidou | Makeup Artist |
| Alexandra Myta | Makeup Department Head |
| Alex Priftis | Hairstylist |
| Kathleen Shugrue | Hairstylist |
| Ioulia Sygrimi | Hair Department Head |
| Marco Ciglia | First Assistant Director |
| Emmelia Chatziandreou | Assistant Director |
| Fanis Nizamis | Set Dresser |
| John Ross | Sound Re-Recording Mixer |
| Anthony Vanchure | Supervising Sound Editor |
| Joe Dzuban | Sound Re-Recording Mixer |
| Ezra Dweck | Sound Effects Editor |
| Sotiris Kraniotis | Stunt Coordinator |
| Spyros Christoforatos | Grip |
| Andonis Goritsas | Grip |
| Giorgos Petrakis | Steadicam Operator |
| Jonathan Spencer | Gaffer |
| Jennifer Schreck | Costume Supervisor |
