 | Natalie Portman als Emma Kurtzman |
 | Ashton Kutcher als Adam Franklin |
 | Kevin Kline als Alvin Franklin |
 | Cary Elwes als Dr. Stephen Metzner |
 | Greta Gerwig als Patrice |
 | Lake Bell als Lucy |
 | Olivia Thirlby als Katie Kurtzman |
 | Ludacris als Wallace |
 | Jake Johnson als Eli |
 | Mindy Kaling als Shira |
 | Talia Balsam als Sandra Kurtzman |
 | Ophelia Lovibond als Vanessa |
 | Guy Branum als Guy |
 | Ben Lawson als Sam |
 | Jennifer Irwin als Megan |
 | Adhir Kalyan als Kevin |
 | Brian H. Dierker als Bones |
 | Abby Elliott als Joy |
 | Vedette Lim als Lisa |
 | Gary David Goldberg als Emma's Relative |
 | Armen Weitzman als Taxi Driver |
 | Shaun Russell als LACMA Guard |
 | Nealla Gordon als Lydia |
 | Seth Morris als Man with Dog |
 | Nasim Pedrad als Writer |
 | Elizabeth Meriwether als Writer |
 | Mollee Gray als Sari |
 | Derek Ferguson als Benji |
 | Matthew Moy als Chuck |
 | Tyne Stecklein als Victoria |
| Kym Connor als Stage Mom |
| Renna Bogdanowicz als Stage Assistant Director |
 | Jennifer Hamilton als On Camera Choreographer |
 | Krystal Ellsworth als Secret High Dancer |
| Kim Marko Germar als Secret High Dancer |
| Megan Honore als Secret High Dancer |
| Nick Lanzisera als Secret High Dancer |
| Moira 'Anjolie' Marfori als Secret High Dancer |
| Dalphe Morantus als Secret High Dancer |
 | Katrina Norman als Secret High Dancer |
| Heather Phillips als Secret High Dancer |
 | Britt Stewart als Secret High Dancer |
| Paula Van Oppen als Secret High Dancer |
 | William Loftis als Secret High Dancer |
 | KC Monnie als Secret High Dancer |
 | Jason Williams als Secret High Dancer |
 | Chulachak Chakrabongse als Bar Group |
| Jay Barclay als Bar Group |
| Tom Tangen als Eli's Dad |
 | Tim Matheson als Eli's Dad #2 |
| Ben Lautman als Rabbi |
| Joshua Andreacola als Boy at Wake |
| Sam Greenberg als Boy at Wake |
| Rachel McDermott als STK Waitress |
| Robert Trapp als Mini-Golfer |
 | Rachael Markarian als Frat Party Dancer |
 | Kherington Payne als Frat Party Dancer |
| Dylan Doornbos Hayes als Young Adam |
 | Stefanie Scott als Young Emma |
| Ivan Reitman | Director |
| Elizabeth Meriwether | Screenplay |
| Joanna Colbert | Casting |
| Conrad E. Palmisano | Stunt Coordinator |
| Paul Sanchez | Camera Operator |
| Chris Fielding | Set Dresser |
| Jorjee Douglass | Makeup Artist |
| Tommy Tancharoen | Transportation Coordinator |
| Joe Medjuck | Producer |
| Rogier Stoffers | Director of Photography |
| Tracey Levy | Makeup Department Head |
| Jacklin Masteran | Key Hair Stylist |
| Christine Colvin | Casting Assistant |
| Omar Hassan-Reep | First Assistant Editor |
| Kyle Salazar | Post Production Assistant |
| Jeff Carson | Music Editor |
| Natalie Portman | Executive Producer |
| Lisa Bruce | Co-Executive Producer |
| Christina Fong | Second Assistant Director |
| Edward Tise | Sound Mixer |
| Max E. Brehme | Property Master |
| Donna Glasser-Hancock | Production Accountant |
| Steve Pederson | Sound Re-Recording Mixer |
| Doug Jackson | Sound Effects Editor |
| Gary Barber | Executive Producer |
| Dana E. Glauberman | Editor |
| Michael Crow | Key Costumer |
| Susan Dukow | Production Coordinator |
| Brent Brooks | Music Editor |
| John Wildermuth | First Assistant Director |
| Danielle Berman | Set Decoration |
| Gregory Alpert | Location Manager |
| Julie Weiss | Costume Design |
| Cristen Carr Strubbe | Unit Production Manager |
| Maria Gonzales | Additional Editing |
| Greg Evans | Set Dresser |
| Ivan Reitman | Producer |
| Ida Random | Production Design |
| Elizabeth Meriwether | Co-Producer |
| Daniel Howell | Hairstylist |
| Chris Squires | Steadicam Operator |
| Wendy Means | Art Department Coordinator |
| Elizabeth Meriwether | Story |
| Tom Pollock | Executive Producer |
| Jane Goldsmith | Script Supervisor |
| Jim Wallis | Set Designer |
| John Hartigan | Special Effects Coordinator |
| Kurt Verbaarschott | Set Dresser |
| Dale Robinette | Still Photographer |
| Roger Birnbaum | Executive Producer |
| John Wildermuth | Associate Producer |
| Greg Berry | Art Direction |
| Robert Jackson | Boom Operator |
| Barbara Lorenz | Hair Department Head |
| Rich Mento | Casting |
| Annette Savitch | Co-Producer |
| Rick A. West | Chief Lighting Technician |
| Kathleen Karridene | Key Makeup Artist |
| Nancy MacLeod | Sound Effects Editor |
| Barbara Harris | ADR Voice Casting |
| Jonathan Glickman | Executive Producer |
| Ken Van Duyne | Assistant Costume Designer |
| Anthony Veader | Hairstylist |
| Heidi Falconer | Unit Publicist |
| Michael J. Benavente | Supervising Sound Editor |
| Tricia Linklater | Assistant Sound Editor |
| Brad Dechter | Orchestrator |
| Anshuman Prasad | Set Designer |
| Michael Samonek | Story |
| Jeffrey Clifford | Producer |
| Ali Bell | Co-Producer |
| Marguerite Pomerhn Derricks | Choreographer |
| Deborah Myles Davis | Costume Supervisor |
| Tess Minsky | Casting Assistant |
| Brad Sherman | Sound Re-Recording Mixer |
| Chuck Michael | Sound Effects Editor |
| Conrad E. Palmisano | Second Unit Director |
| John Debney | Original Music Composer |
| R.J. Kizer | Dialogue Editor |
| Susan Dudeck | Dialogue Editor |
| Larry Kemp | Dialogue Editor |
| Greg Zimmerman | ADR Recordist |
| Sarah Monat | Foley Artist |
| Robin Harlan | Foley Artist |
| Randy Singer | Foley Mixer |
| Robbie Nevil | Musician |
| Melissa R. Stubbs | Stunt Driver |
| Jimmy N. Roberts | Stunts |
