 | Frayne Rosanoff als John Cooper |
 | Robert Englund als Dr. Anton Rudolph |
 | William Zabka als Greg Larsen |
 | Dana Barron als Kristin |
 | Sara Mornell als Theresa |
 | Wil Wheaton als Tommy |
 | Casper Van Dien als Bart Parker |
 | Jenny McCarthy-Wahlberg als Francesca Garibaldi |
 | Chris Owens als Brian Cooper |
 | Sean Whalen als Deputy Lewis Ross |
 | Gary Grubbs als Sheriff Griffin Wade |
 | John Franklin als Floyd Fuller |
| Theo Nicholas Pagones als Dootsen |
 | Keith Coogan als Lenny |
 | LoriDawn Messuri als Lisa Johnson |
 | Kathleen Randazzo als Roberta Keeler |
| Scott Williamson als Kenny Summers |
 | Ed Lauter als Pilot |
 | Marc McClure als Co-Pilot |
 | Frank Welker als The Python (voice) |
| Natasha Roth als Little Girl in Park |
| Robert Lepucki als Bravo Leader |
| Trevor Baer als Billy |
| Lisa Michele Jones als NSA Agent |
| Richard Clabaugh | Director |
| Ken Olandt | Producer |
| Jeffery Beach | Producer |
| Paul Bogh | Screenplay |
| Phillip J. Roth | Story |
| Chris Neal | Screenplay |
| Gary Hershberger | Screenplay |
| James Hollensteiner | Executive Producer |
| Thomas J. Niedermeyer Jr. | Executive Producer |
| Richard Smith | Executive Producer |
| Daniel Nielsen | Music |
| Patrick Rousseau | Director of Photography |
| Christian McIntire | Editor |
| David Huang | Production Design |
| Roger Baer | Art Direction |
| Eden Barr | Set Decoration |
| Francie Hart | Makeup Department Head |
| Yulia Gershenzon | Costume Design |
| Phillip J. Roth | Producer |
| Jennifer M. Byrne | Production Coordinator |
| Melanie J. Elin | Line Producer |
| Plamen Voynovsky | Co-Producer |
| Teal Druda | Assistant Makeup Artist |
| Angela Beach | Production Supervisor |
| Melanie J. Elin | Unit Production Manager |
| Nannette Troutman | Casting |
| Paul Bogh | First Assistant Director |
| Christian McIntire | Second Unit Director |
| James H. Coburn IV | Sound Mixer |
| Bill Reinhardt | Sound Mixer |
| James Bailey | Foley Artist |
| Ron Otis | Stunt Coordinator |
| Yulia Gershenzon | Costumer |
| Robert Lepucki | Location Manager |
| Mike Tristano | Weapons Master |
| Marc Fehse | Production Assistant |
| Debbie Evans | Stunts |
| Kurt Bryant | Stunts |
| David Brinton | Stunts |
| Anthony Kramme | Stunts |
| Patrick J. Statham | Stunts |
| Susan Purkhiser | Stunts |
| John Cappilla | Gaffer |
| Russell Griffith | Second Unit Director of Photography |
| J.M. Logan | Animatronic and Prosthetic Effects |
| Chad Wilson | Steadicam Operator |
| Thomas Vozza | Still Photographer |
