 | Matt Damon als Gardner Lodge |
 | Julianne Moore als Margaret Lodge / Rose |
 | Noah Jupe als Nicky Lodge |
 | Oscar Isaac als Bud Cooper |
 | Landon Gordon als Kid on Bike |
 | Glenn Fleshler als Ira Sloan |
 | Alex Hassell als Louis |
 | Karimah Westbrook als Mrs. Mayers |
 | Tony Espinosa als Andy Mayers |
 | Leith M. Burke als Mr. Mayers |
 | Gary Basaraba als Uncle Mitch |
 | Jack Conley als Hightower |
 | Megan Ferguson als June |
 | Lauren Burns als Mitch's Secretary |
 | Steve Monroe als Mailman Henry |
 | James Handy als Mayor Billings |
 | Hope Banks als Mrs Pendalton |
 | Michael D. Cohen als Stretch |
 | Richard Kind als John Sears |
 | Cathy Giannone als Sylvia |
 | Peggy Miley als Betty |
 | Ellen Crawford als Eileen |
 | Nancy Daly als Linda |
 | Pamela Dunlap als Mrs. Krup |
 | Mather Zickel als James |
 | Josh Meyer als Freddy |
 | Vince Cefalu als Chuck |
 | Corey Allen Kotler als Bomber |
| Steven Shaw als Doctor Jennings |
 | Don Baldaramos als Reverend Jones |
 | Allan Wasserman als Roger |
| Mark Leslie Ford als Bill Thackery |
| Robert Pierce als Ed Pappas |
| Frank Califano als Father Dominicus |
 | Biff Yeager als Mr. Karger |
| Benjamin Franczuszki als Reporter |
 | Inbal Amirav als Church Choir Singer (uncredited) |
 | Dean England als Funeral Mourner (uncredited) |
| Gia Balzano als Mississippi Younger Daughter (uncredited) |
| Becca Beton als New York Girl (uncredited) |
 | Saraya Chanadet als Ohio Daughter (uncredited) |
| Diane Dehn als Virginia (uncredited) |
 | Gretchen Dickason als Passers by (uncredited) |
| Nichole Eberle als Neighbor/Protester (uncredited) |
 | Sonia Gascón als Pregnant Lady (uncredited) |
| Anna Gion als Smoking Pregnant Woman (uncredited) |
| Lauren Mendoza als P & S Secretary (uncredited) |
| Diana Matlak als Funeral Mourner (uncredited) |
| Taylor Ragan als Mississippi Mom (uncredited) |
 | Weston Mueller als Perp #1 (uncredited) |
 | Alessandro Delpiano als Townhome kid (uncredited) |
 | Dash Williams als Walters (uncredited) |
| Gavin Wilde als Cowboy Kid |
 | Avery Barkdull als Grocery Store Kid (uncredited) |
 | Blake Altounian als Frog (uncredited) |
| Bobby Brodney als Reporter (uncredited) |
| Bethany Haynes | Other |
| Joel Coen | Writer |
| George Clooney | Director |
| Ethan Coen | Writer |
| James D. Bissell | Production Design |
| Susanne Scheel | Casting Associate |
| George Clooney | Producer |
| Ken Haber | Location Scout |
| Ellen Chenoweth | Casting |
| Jeff Winn | Craft Service |
| Kathy M. Berry | Location Scout |
| Teddy Schwarzman | Producer |
| Joel Silver | Executive Producer |
| Grant Heslov | Producer |
| Karen Teneyck | Other |
| Carrie Prince | Other |
| Michael J. Burmeister | Location Manager |
| Brent Rice | Leadman |
| Bryan Persichetti | Finance |
| Robert Elswit | Director of Photography |
| David Webb | Co-Producer |
| Barbara A. Hall | Executive Producer |
| Victor Hadida | Co-Executive Producer |
| Hal Sadoff | Executive Producer |
| Samuel Hadida | Co-Executive Producer |
| Stephen Mirrione | Editor |
| Hilary Bronwyn Gayle | Still Photographer |
| Christa Munro | Supervising Art Director |
| Michael Gowen | Assistant Art Director |
| Diane H. Newman | Script Supervisor |
| Claire Raskind | Unit Publicist |
| Yeşim "Shimmy" Osman | Hairstylist |
| David Webb | First Assistant Director |
| Rusty Davis | Grip |
| Vince Manocchia | Electrician |
| Alan Burg | Set Dresser |
| Jeff Hay | Set Dresser |
| Tim James | Stunts |
| Kevin Michael Murphy | Stunts |
| Alastair Grimshaw | Visual Effects Editor |
| Ellen Vieira | Makeup Artist |
| Michael Brown | Painter |
| Noelle King | Set Designer |
| Matt Kasmir | Visual Effects Supervisor |
| Colin Anderson | Steadicam Operator |
| Patrick Hoeschen | Electrician |
| Corey Bronson | Set Costumer |
| Charlotte Gleason | Set Production Assistant |
| Julie Hewett | Makeup Department Head |
| Greg Fitzpatrick | Stunts |
| Jesse D. Vogel | Painter |
| Fante Zamora | Set Dresser |
| Mitchell Ray Kenney | Costume Supervisor |
| Kelly Porter (costumer) | Set Costumer |
| Edward Tise | Sound Mixer |
| Brendon O'Dell | Special Effects Supervisor |
| Tim Neff | Stunts |
| Erin Sahlstrom | Production Coordinator |
| Darlene Brumfield | Key Hair Stylist |
| George A. Sack | Transportation Coordinator |
| Brian Stackhouse | Driver |
| Randi Mavestrand | Makeup Artist |
| Colin Anderson | Camera Operator |
| Chelsea Dinsdale | Assistant Editor |
| Erik Coutts | Driver |
| Jan Pascale | Set Decoration |
| Jenny Eagan | Costume Design |
| Aurora Bergere | Key Makeup Artist |
| Eric Richard Lasko | Second Assistant Director |
| Chris Snyder | Construction Coordinator |
| Richard Fox | Digital Compositors |
| Jessica Albertson | Assistant Costume Designer |
| Matthew Cavaliero | Property Master |
| Bogdan Iofciulescu | Techno Crane Operator |
| Emily Skelton | Driver |
| Dominic Pacitti | Set Production Assistant |
| Bob Renna | Set Dresser |
| Brett Easton | Stunts |
| Jeffrey Lee Gibson | Stunt Coordinator |
| Deborah Harman | Set Dresser |
| Randall L. Johnson | Boom Operator |
| Peewee Piemonte | Stunts |
| Hugh McCallum | Grip |
| Debs Richardson | Assistant Editor |
| Charlotte Townsend | Set Production Assistant |
| Richard Redlefsen | Makeup Artist |
| Rocco Francesco Paolone | Painter |
| Vincent Piemonte | Stunts |
| Jackie Eco | Stand In |
| Bradford Ralston | Video Assist Operator |
| Ellen J. Hornstein | Assistant Production Coordinator |
| Lois Yaroshefsky | Studio Teachers |
| Alexandre Desplat | Original Music Composer |
| George Clooney | Writer |
| Grant Heslov | Writer |
| Mike Revell | Production Accountant |
| Erik Audé | Stunts |
| Cookie Lopez | Costumer |
| Oliver Tarney | Supervising Sound Editor |
| Mark Taylor | Sound Re-Recording Mixer |
| Paul Massey | Sound Re-Recording Mixer |
| Dawn Gough | Sound Editor |
| James Harrison | Sound Effects Designer |
| Jill Beecher | Assistant Art Director |
| Steve Gindorf | Construction Foreman |
| Nick Jimenez | ADR Recordist |
| Barbara A. Hall | Unit Production Manager |
| J. Elizabeth Ingram | Production Supervisor |
| Bobby Johanson | ADR Mixer |
| David Marnell | Second Second Assistant Director |
| Peter Burgis | Foley Artist |
| Meg Clark | Post Production Supervisor |
| Christy Busby | Second Second Assistant Director |
| Jill Beecher | Graphic Designer |
| Zoe Freed | Foley Artist |
| John Youngblood | Assistant Property Master |
| Lilly Blazewicz | Foley Editor |
| Michael A. Truesdale | Art Department Coordinator |
| Glen Gathard | Foley Mixer |
| Rachael Tate | ADR & Dubbing |
| Anthony Keating | Production Assistant |
