 | Jessica Tuck als Chris (voice) |
 | Chris Young als Rob (voice) |
 | Roger Kabler als Radio (voice) |
 | Deanna Oliver als Toaster (voice) |
 | Eric Lloyd als Blanky (voice) |
 | Thurl Ravenscroft als Kirby (voice) |
 | Andy Daly als Murgetroid (voice) |
| Jonathan Benair als Jim Bob (voice) |
 | Timothy Stack als Lampy (voice) |
 | Andy Milder als Ratso (voice) |
 | Alfre Woodard als Maisie (voice) |
 | Danny Nucci als Alberto (voice) |
 | Eddie Bracken als Sebastian (voice) |
 | Jay Mohr als Mack (voice) |
 | Kevin Meaney als Computer (voice) |
 | Victoria Jackson als Mouse (voice) |
 | Eddie Deezen als Charlie (voice) |
 | Brian Doyle-Murray als Wittgenstein (voice) |
 | Paddi Edwards als Lab Computer (voice) |
| Ross Mapletoft als Modem (voice) |
| Marc Allen Lewis als Security Guard (voice) |
 | Laurel Green als Campus Student (voice) |
 | Aretha Franklin als Homebuilt Computer / Singer (voice) |
 | Anndi McAfee als Little Girl (voice) |
 | Neil Ross als Security Camera / Police Man (voice) |
 | Roz Ryan als Computer Parts / Singer / Additional Voices (voice) |
| John Dillon | Visual Effects Supervisor |
| Jeff Johnson | Animation |
| Willard Carroll | Story |
| Willard Carroll | Screenplay |
| Robert C. Ramirez | Director |
| Donald Kushner | Producer |
| Craig Kellman | Character Designer |
| Dave Dunnet | Layout Supervisor |
| Bari Greenberg | Animation |
| Julian Chaney | Character Designer |
| John Jenkins | Character Designer |
| Robert C. Ramirez | Character Designer |
| John Dillon | Effects Supervisor |
| Thomas M. Disch | Characters |
| Jerry Rees | Characters |
| Joe Ranft | Characters |
| Mark McGroarty | Production Manager |
| Julie Ann Lau | Editor |
| William Finn | Music |
| Ellen Fitzhugh | Lyricist |
| Alexander Janko | Original Music Composer |
| Alexander Janko | Conductor |
| Brian Chavanne | Casting Director |
| Mary Hidalgo | Casting Director |
| Dave Dunnet | Art Direction |
| Brigitte Strother | Colorist |
| Kurt Albrecht | Co-Producer |
| Willard Carroll | Executive Producer |
| Peter Locke | Executive Producer |
