 | Amy Poehler als Abby |
 | Maya Rudolph als Naomi |
 | Rachel Dratch als Rebecca |
 | Ana Gasteyer als Catherine |
 | Paula Pell als Val |
 | Emily Spivey als Jenny |
 | Tina Fey als Tammy |
 | Jason Schwartzman als Devon |
 | Maya Erskine als Jade |
 | Liz Cackowski als Lisa (Sommelier) |
 | Rachel Hamilton als Bartender |
 | Cherry Jones als Lady Sunshine |
 | Brené Brown als Herself |
 | Jon Glaser als TED Talk (voice) |
 | Craig Cackowski als Mason (Sommelier) |
 | Kate Comer als Clem |
 | R.J. Walker als Pray |
 | Janine Brito als Kira |
 | Sunita Mani als Dolly |
 | Jason Greene als Freckle |
 | Santina Muha als Dr. Melton Receptionist (voice) |
 | Greg Poehler als Doctor Dickswing |
 | Caitlin Arend als Young Abby (uncredited) |
| Elise Robson als Young Catherine (uncredited) |
 | Hannah Bamberg als Catherine's Assistant (uncredited) |
 | Ryan Shukis als Waiter (uncredited) |
| Amy Poehler | Director |
| Emily Spivey | Writer |
| Amy Poehler | Producer |
| Carla Hacken | Producer |
| Morgan Sackett | Producer |
| Liz Cackowski | Writer |
| Tom Magill | Director of Photography |
| Julie Monroe | Editor |
| Lisa Coleman | Music |
| Wendy Melvoin | Music |
| David Hyman | Co-Producer |
| Emily Spivey | Co-Producer |
| Liz Cackowski | Co-Producer |
| Kirston Mann | Costume Designer |
| Keith P. Cunningham | Production Design |
| Amy Poehler | Story |
| Emily Spivey | Story |
| Liz Cackowski | Story |
| Haley Sweet | Unit Production Manager |
| David Hyman | Unit Production Manager |
| Steve Day | First Assistant Director |
| Jeff Rosenberg | Second Assistant Director |
| Wade Allen | Stunt Coordinator |
| Heidi Pascoe | Stunt Double |
| Lisa Dempsey | Stunt Double |
| Wylie Stateman | Sound Designer |
| Eric Hoehn | Sound Designer |
| Eric Hoehn | Sound Re-Recording Mixer |
| Lindsey Alvarez | Sound Re-Recording Mixer |
| Richard B. Molina | Assistant Editor |
| Jenny Caceres | Assistant Editor |
| Doug Smith | Production Supervisor |
| Andrea Wertheim | Post Production Supervisor |
| Jeffrey Kalmus | Visual Effects Supervisor |
| Bradley Rubin | Art Direction |
| Brittany Bradford | Assistant Art Director |
| Kama Hayes | Art Department Coordinator |
| Martha Johnston | Set Designer |
| Stephanie Charbonneau | Graphic Designer |
| Kate Emery | Graphic Designer |
| Josh Sheppard | Storyboard Artist |
| Andrea Mae Fenton | Set Decoration |
| Steve MacMillin | Leadman |
| Shawn Charles Smithson | Set Dresser |
| Shant Balkian | Set Dresser |
| Mark W. Pallatt | Set Dresser |
| Mike Suhy | Set Dresser |
| Chris Peterson | Set Dresser |
| Chris Kennedy | Set Dresser |
| Gay Perello | Property Master |
| Julie Witherington | Assistant Property Master |
| Ari Robbins | Steadicam Operator |
| Suzanne Bingham | Script Supervisor |
| Sylvain Lasseur | Sound Effects Designer |
| Leo Marcil | Sound Effects Designer |
| Ian Broucek | Music Supervisor |
| Jenny Barak | Music Editor |
| Joel S. Reidy | Boom Operator |
| Luci Romberg | Stunt Double |
