 | Peter Weller als Officer Alex J. Murphy / RoboCop |
 | Nancy Allen als Officer Anne Lewis |
 | Dan O'Herlihy als The Old Man |
 | Ronny Cox als Dick Jones |
 | Kurtwood Smith als Clarence Boddicker |
 | Miguel Ferrer als Bob Morton |
 | Robert DoQui als Sgt. Warren Reed |
 | Ray Wise als Leon Nash |
 | Felton Perry als Johnson |
 | Paul McCrane als Emil Antonowsky |
 | Jesse D. Goins als Joe Cox |
 | Del Zamora als Kaplan |
 | Calvin Jung als Steve Minh |
 | Rick Lieberman als Walker |
 | Lee de Broux als Sal |
| Mark Carlton als Miller |
 | Edward Edwards als Manson |
 | Michael Gregory als Lt. Hedgecock |
 | Freddie Hice als Bobby |
 | Neil Summers als Dougy |
 | Gene Wolande als Prisoner |
| Gregory Poudevigne als Slimey Lawyer |
 | Charles Carroll als Bail Bondsman |
 | Kevin Page als Kinney |
| Yolonda Williams als Ramirez |
 | Tyrees Allen als Starkweather |
 | John S. Davies als Chessman |
| Laird Stuart als Cecil the Clerk |
| Stephen Berrier als Roosevelt |
 | Sage Parker als Tyler |
| Karen Radcliffe als Technician #1 |
 | Darryl Cox als Technician #2 |
 | Jerry Haynes als Dr. McNamara |
| Bill Schockley als Creep |
 | Donna Keegan als Rape Victim |
 | Mike Moroff als Hophead |
| Marjorie Rynearson als Grocery Mom |
| Jo Livingston als Grocery Pop |
 | Joan Pirkle als Barbara |
 | Diane Robin als Chandra |
 | Adrianne Sachs als Tawney |
| Maarten Goslins als Salesman |
 | Angie Bolling als Murphy's Wife |
| Jason Levine als Murphy's Son |
 | S.D. Nemeth als Bixby Snyder |
 | Bill Farmer als Justin Ballard-Watkins |
| Michael Hunter als Peter the Homeowner |
| Spencer Prokop als Gas Station Attendant |
| Debra Zach als Nurse |
| L.J. King als Emergency Doctor |
 | David Packer als Emergency Doctor |
 | Leeza Gibbons als Jesse Perkins |
 | Mario Machado als Casey Wong |
 | Bill Blair als Undercover Cop (uncredited) |
| Don "Tex" Clark als Boardroom Executive (uncredited) |
 | Gilbert B. Combs als Sal's Gunman (uncredited) |
| Jon Davison als ED-209 (voice) (uncredited) |
 | Wanda De Jesus als Estevez (uncredited) |
| James Field als Restroom Junior Executive (uncredited) |
| John Garrett als News Crew (uncredited) |
 | Allan Graf als Sal's Bodyguard (uncredited) |
 | Katie Griffin als Young Girl (uncredited) |
 | Harry Johnson als Dad in Nuke-'em' Commercial (uncredited) |
 | Debra Lamb als Pizza Dough Juggling Girl (uncredited) |
 | John Landis als Man in '6000 SUX' Commercial (uncredited) |
 | Randall Oliver als S.W.A.T. Team Member (uncredited) |
| Scott Sligar als S.W.A.T. Team Member (uncredited) |
| James Staszkiel als Keva Rosenberg (uncredited) |
 | Scott Thomson als Blonde Thug (uncredited) |
 | Paul Verhoeven als Dancer at Disco (uncredited) |
| Mark Edward Walters als Street Kid (uncredited) |
| Sean Wohland als Nukem (uncredited) |
| Paul Verhoeven | Director |
| Arne Schmidt | Producer |
| Basil Poledouris | Original Music Composer |
| Jost Vacano | Director of Photography |
| Russell Towery | Stunts |
| Randy Fife | Stunts |
| Frank Ferrara | Stunts |
| Vickie Creach | Stunts |
| Mike Shanks | Stunts |
| Jamie Bunch | Stunts |
| Jackie Resch | Stunts |
| Gary Combs | Stunt Coordinator |
| Edward Neumeier | Writer |
| Sally Dennison | Casting |
| Michael Miner | Writer |
| Edward Neumeier | Co-Producer |
| Phil Tippett | Associate Producer |
| Stephen Lim | Associate Producer |
| Jon Davison | Executive Producer |
| Frank J. Urioste | Editor |
| Julie Selzer | Casting |
| William Sandell | Production Design |
| Rob Bottin | Makeup Effects |
| Margaret Prentice | Makeup Effects |
| Phil Tippett | Visual Effects |
| John Marshall | Art Direction |
| Gayle Simon | Art Direction |
| Robert Gould | Set Decoration |
| Erica Edell Phillips | Costume Design |
| Bonnie Clevering | Hairstylist |
| Fred Lackey III | Hairstylist |
| Carla Palmer | Makeup Artist |
| Rob Bottin | Makeup Effects Designer |
| Stephan Dupuis | Prosthetic Designer |
| Bart Mixon | Makeup Effects Designer |
| Margaret Prentice | Makeup Effects Designer |
| Steve Bartlett | Sound Designer |
| Michael J. Benavente | Sound Editor |
| James Christopher | Sound Editor |
| Carlos Delarios | Sound Re-Recording Mixer |
| Donald Flick | Sound Editor |
| Stephen Hunter Flick | Sound Editor |
| Avram D. Gold | Sound Editor |
| Michael J. Kohut | Sound Re-Recording Mixer |
| John Pospisil | Sound Editor |
| Aaron Rochin | Sound Re-Recording Mixer |
| Robert Wald | Sound Mixer |
| David A. Whittaker | Sound Editor |
| Dan Sharp | Sound Re-Recording Mixer |
| Peter Kuran | Visual Effects |
| Rob Bottin | Visual Effects |
| Rocco Gioffre | Matte Painter |
| Charles Newirth | Production Manager |
| Dale L. Martin | Special Effects |
| Michele Panelli-Venetis | First Assistant Director |
| Allegra Clegg | Production Coordinator |
| David B. Householter | Second Assistant Director |
| Paula Squires Asaff | Script Supervisor |
| Anette Haellmigk | First Assistant Camera |
| Deana Newcomb | Still Photographer |
| Robert Driskell | Gaffer |
| James E. Tocci | Set Designer |
| Erica Rogalla | Set Dresser |
| Bill MacSems | Property Master |
| Randy E. Moore | Weapons Master |
| William Purcell | Special Effects |
| Keith Richins | Special Effects |
| Lawrence A. Aeschlimann | Special Effects |
| Joan Thomas | Costume Supervisor |
| Janet Lucas Lawler | Costumer |
| Kerry Rike | Key Grip |
| John Knight | Key Grip |
| Don Broughton | Boom Operator |
| Brian Cowden | Location Manager |
| Craig Pointes | Location Manager |
| Diane L. Greenwalt | Location Manager |
| Alvin Milliken | Transportation Coordinator |
| Dennis W. Milliken | Transportation Captain |
| E.W. Bradford | Construction Coordinator |
| Jerry G. Henery | Construction Foreman |
| Larry Langley | Construction Foreman |
| Teressa Longo | Assistant Editor |
| Florent Danny Retz | First Assistant Editor |
| Tom Villano | Music Editor |
| Bundy Chanock | Set Medic |
| Joe Finnegan | Stunts |
| Sol Negrin | Additional Photography |
| Greg Wayne Elam | Stunts |
| Debbie Evans | Stunts |
| Jeannie Epper | Stunt Double |
| Gene LeBell | Stunts |
| Johnny Gutierrez | Gaffer |
| Spiro Razatos | Stunts |
| Freddie Hice | Stunts |
| Gilbert B. Combs | Stunts |
| Miles Teves | Conceptual Illustrator |
| Mark Goldblatt | Second Unit Director |
