 | Steven Pasquale als Dallas Howard |
 | Reiko Aylesworth als Kelly O'Brien |
 | John Ortiz als Sheriff Eddie Morales |
 | Johnny Lewis als Ricky |
 | Ariel Gade als Molly O'Brien |
 | Kristen Hager als Jesse |
 | Sam Trammell als Tim |
 | Robert Joy als Col. Stevens |
 | David Paetkau als Dale |
 | Tom Woodruff Jr. als Alien |
 | Ian Whyte als Predator |
 | Chelah Horsdal als Darcy |
 | Meshach Peters als Curtis |
 | Matt Ward als Mark |
 | David Hornsby als Drew |
 | Chris William Martin als Deputy Ray |
 | James Chutter als Deputy Joe |
| Phil Buhler als Deputy |
 | Kevin Haaland als Deputy |
 | Gina Holden als Carrie |
 | Kurt Max Runte als Buddy |
 | Liam James als Sam |
 | Tim Henry als Dr. Lennon |
 | Tom McBeath als Karl |
 | Ty Olsson als Nathan |
 | Anthony Harrison als Ritchie |
 | Lloyd Berry als Homeless Harry |
 | Rekha Sharma als Nurse Helen |
 | Catherine Lough Haggquist als Tina |
 | Victoria Bidewell als Pregnant Sue |
 | Dalias Blake als Lt. Wood |
 | Tim Perez als Mr. Thomas |
 | Rainbow Sun Francks als Earl |
 | Juan Riedinger als Scotty |
 | Val Cole als Broadcaster |
 | Andrew Hedge als Tank Driver |
 | Ryan Robbins als Truck Driver |
 | Curtis Caravaggio als Special Forces Commander |
 | Françoise Yip als Ms. Y |
 | John Wardlow als Homeless Guy |
 | Nesta Chapman als Homeless Lady |
| Ian Feuer als Additional Predator |
 | Bobby 'Slim' Jones als Additional Predator |
 | Glen Brkich als National Guard |
| Jay-Lyn Green als Pregnant Woman |
 | Lili Wexu als Pregnant Woman |
 | Adrian Hough als ER Resident Doc |
| Karen van Blankenstein als ER Doctor #2 |
 | Shareeka Epps als Kendra (uncredited) |
| Michal Suchánek als Nick |
| Colin Strause | Director |
| Greg Strause | Director |
| John Davis | Producer |
| Brian Tyler | Original Music Composer |
| Daniel Pearl | Director of Photography |
| Dan Zimmerman | Editor |
| Heike Brandstatter | Casting |
| Mindy Marin | Casting |
| Coreen Mayrs | Casting |
| Andrew Neskoromny | Production Design |
| David Giler | Producer |
| Jim Thomas | Characters |
| John Thomas | Characters |
| Shane Salerno | Screenplay |
| Walter Hill | Producer |
| Shane Vieau | Set Decoration |
| Angus Strathie | Costume Design |
| Ryan Ostiguy | Scenic Artist |
| Helen Jarvis | Supervising Art Director |
| Dan O'Bannon | Characters |
| Ronald Shusett | Characters |
| Sharon Thompson | Art Department Coordinator |
| Matthew Pomerantz | Construction Coordinator |
| John Beatty | Construction Coordinator |
| Chris Beach | Set Designer |
| Niki Charalambopoulo | Scenic Artist |
| Renee Dundas | Scenic Artist |
| Janette Hyland | Scenic Artist |
| Roderick MacDonald | Scenic Artist |
| Giovanni Pasqua | Scenic Artist |
| Camar Sterling | Scenic Artist |
| Martina Javorova | Assistant Art Director |
| Jessee J. Clarkson | Sculptor |
| Andrew Li | Assistant Art Director |
| Jack Gauvreau | Sculptor |
| Jim Brookshire | Supervising Sound Editor |
| Jay Wilkinson | Supervising Sound Editor |
| Ron Bartlett | Sound Re-Recording Mixer |
| Doug Hemphill | Sound Re-Recording Mixer |
| Tony Lazarowich | Special Effects Coordinator |
| Ryan Chavez | Visual Effects Editor |
| Mohsen Eletreby | Visual Effects Editor |
| Rob Hodgson | Visual Effects Supervisor |
| Eric Mises-Rosenfeld | Visual Effects Supervisor |
| Colin Strause | Visual Effects Supervisor |
| Kendrick Wallace | Visual Effects Producer |
| J.J. Makaro | Stunt Coordinator |
| James Dittiger | Still Photographer |
| Stuart Haggerty | Gaffer |
| Niall Fraser | Best Boy Electric |
| Wayne MacConnell | Camera Operator |
| Don Reddy | Camera Operator |
| Ian Seabrook | Underwater Camera |
| Joe Lisanti | Music Editor |
| Sylvia Nablo | Transportation Coordinator |
| S. Steven Sach | Location Manager |
| Hans Bjerno | Helicopter Camera |
| Leonard F.W. Green | Digital Effects Supervisor |
| James Bamford | Stunts |
| Kelly Moon | Script Supervisor |
| Jena Niquidet | Production Coordinator |
| Patrick Ramsay | Sound mixer |
| Trinh Tran | Production Assistant |
| Terry Weaver | Property Master |
| Eric Flickinger | Sound Recordist |
| John T. Cucci | Foley Artist |
| Dan O'Connell | Foley Artist |
| Benjamin Beardwood | Dialogue Editor |
| Robbie Brenner | Executive Producer |
| Paul Deason | Executive Producer |
| Warren Carr | Unit Production Manager |
| Paul Deason | Unit Production Manager |
| Chris Dowell | Post Production Supervisor |
| Drew Locke | Unit Manager |
| David McKimmie | Post Production Supervisor |
| Tarnya Cook | Third Assistant Director |
| Jeff Habberstad | Second Unit Director |
| Kathy Houghton | Second Assistant Director |
| Katherine Keizer | Additional Third Assistant Director |
| Janine Law | Second Assistant Director |
| Jennifer Nelson | Third Assistant Director |
| Jody Ryan | Third Assistant Director |
| Ken Shane | First Assistant Director |
| Lars P. Winther | First Assistant Director |
| Adam J. Piechnik | Background Casting Director |
| Ian C. Ballard | First Assistant Hairstylist |
| Beth Boxall | First Assistant Makeup Artist |
| Linda Jones | Key Hair Stylist |
| Debra Wiebe | Key Hair Stylist |
| Jayne Dancose | Key Makeup Artist |
| Sally Barnes | Key Makeup Artist |
| Lori West | Art Department Assistant |
| Brian Epp | Assistant Property Master |
| Kevin Tomecek | Construction Buyer |
| Dale Menzies | Construction Foreman |
| Sally Hudson | Graphic Designer |
| Kevin Clark | Greensman |
| David Valentine | Property Master |
| Simon Haywood-Anderson | Set Dresser |
| Richard Bennett | Storyboard Artist |
| Danelle Davenport | Storyboard Artist |
| John Cluff | Pyrotechnician |
| Hans Bjerno | Aerial Director of Photography |
| Matt Almas | Best Boy Grip |
| Lee Gibeau | Best Boy Grip |
| Peter Wilke | Camera Operator |
| Neil McBride | Dolly Grip |
| Russell Hawkes | Dolly Grip |
| Todd Hlagi | Dolly Grip |
| Reg Gole | First Assistant Camera |
| Simon Jori | First Assistant Camera |
| Sandes Ashe | First Assistant Camera |
| Sean Elliott | First Assistant Camera |
| David S. Warner | Gaffer |
| Roger Bailey | Generator Operator |
| Monty Black | Generator Operator |
| Keith Flanagan | Grip |
| Wally Nygren | Grip |
| Carlos Avilila | Grip |
| Tony Whiteside | Key Grip |
| John Le Roy | Key Grip |
| Peter Pacula | Key Rigging Grip |
| Jordan Johnson | Lighting Technician |
| Kris Tobiasson | Lighting Technician |
| Rod Haney | Rigging Grip |
| Cole Koehler | Second Assistant Camera |
| Richard Sinclair | Second Assistant Camera |
| Thomas Yardley | Second Assistant Camera |
| Sasha Proctor | Second Assistant Camera |
| Leigh Jenkins | Second Assistant Camera |
| David McKnight | Video Assist Operator |
| Casey MacIntyre | Video Assist Operator |
| Kenny Becker | Color Timer |
| Curtis Lindersmith | Digital Intermediate Editor |
| Loan Phan | Digital Intermediate Producer |
| Trinh Tran | Editorial Production Assistant |
| Stephanie Denatale | Editorial Production Assistant |
| Steven Flegel | Editorial Production Assistant |
| Ian Silverstein | First Assistant Editor |
| Kirk Moses | First Assistant Editor |
| Gary Burritt | Negative Cutter |
| Sandra J. Blackie | Costume Coordinator |
| Petra Bergholz | Costumer |
| Sarah Haddleton | Costumer |
| Charis Tillson | Costumer |
| Heather Rupert | Costumer |
| Kieu Nguyen | Seamstress |
| Nora Bautista | Seamstress |
| Gloria Chan | Seamstress |
| Petra Wright | Seamstress |
| Christa Richards | Seamstress |
| John Denison | Truck Costumer |
| Marnie Ander | Truck Costumer |
| Caitlin McKenna | ADR Voice Casting |
| Meagan Lopez | Casting Assistant |
| Trica Thompson | Casting Assistant |
| Andrea Brown | Extras Casting |
| Brad McLaughlin | Animation |
| Joshua Cordes | Animation Supervisor |
| Bill Kunin | Compositing Supervisor |
| Laura Sevilla | Compositing Supervisor |
| Eric Almeras | Digital Compositor |
| Mathias Frodin | Digital Compositor |
| Vinh Nguyen | Digital Compositor |
| Hirofumi Takeda | Digital Compositor |
| Go Woon Choi | Modeling |
| Tamer Eldib | Modeling |
| Atsushi Imamura | Modeling |
| Justin Louis | Modeling |
| Chris Radcliffe | Modeling |
| Chun Seong Ng | Modeling |
| Miguel A. Guerrero | Modeling |
| Tanissa Potrovitza Schoen | Pre-Visualization Coordinator |
| Bryce Brecheisen | Visual Effects Coordinator |
| Jeff Atherton | Visual Effects Coordinator |
| Yasamin Ismaili | Visual Effects Coordinator |
| Katie Spinelli | Visual Effects Coordinator |
| Ryan Zuttermeister | Visual Effects Coordinator |
| William H.D. Marlett | Visual Effects Coordinator |
| Greg Strause | Visual Effects Supervisor |
| David Penikas | Animatronics Supervisor |
| Derek Casari | ADR Engineer |
| Jan Petrov | ADR Recordist |
| Jason P. Dass | Assistant Sound Editor |
| Ken Lee | Boom Operator |
| Naan Spiess | Cableman |
| Skip Longfellow | First Assistant Sound Editor |
| James Ashwill | Foley Mixer |
| Richard Duarte | Foley Mixer |
| Frank Smathers | Foley Supervisor |
| Greg Hannas | Sound Assistant |
| Simon Coke | Sound Effects Editor |
| Jason Crosby | Marine Coordinator |
| Jim Filippone | Aerial Coordinator |
| Ryan Steacy | Armorer |
| Rob Fournier | Armorer |
| Jason Bogard | Production Accountant |
| Ali Pounder | Production Secretary |
| Fleur Western | Production Secretary |
| Dixie Cutler | Unit Publicist |
| Eli Zagoudakis | Stunts |
| Rhys Williams | Stunts |
| Melissa R. Stubbs | Stunts |
| Raymond Sammel | Stunts |
| Jeffrey C. Robinson | Stunts |
| Gerald Paetz | Stunts |
| Reg Milne | Stunts |
| Cody Laudan | Stunt Double |
| Michael Langlois | Stunts |
| Jon Kralt | Stunts |
| Trevor Jones | Stunts |
| Dave Hospes | Stunt Coordinator |
| Andrew Michael Hill | Stunts |
| Corry Glass | Stunts |
| Lani Gelera | Stunts |
| Caroline Field | Stunts |
| Marny Eng | Stunts |
| Austin Dunn | Stunts |
| Duane Dickinson | Stunts |
| John DeSantis | Stunts |
| Mike Desabrais | Stunts |
| Daniel Cudmore | Stunts |
| Laura Lee Connery | Stunts |
| Mike Ching | Stunts |
| Colby Chartrand | Stunts |
| Doug Chapman | Stunts |
| Mia Carriconde | Stunts |
| Yves Cameron | Stunts |
| Simon Burnett | Stunts |
| Rob 'Sluggo' Boyce | Stunts |
| Loyd Bateman | Stunts |
| Carolyn Anderson | Stunts |
| Trevor Addie | Stunts |
| Lloyd Adams | Stunts |
| Chris Wells | CG Supervisor |
| H. R. Giger | Creature Design |
