 | Viggo Mortensen als Frank Hopkins |
 | Zuleikha Robinson als Jazira |
 | Omar Sharif als Sheikh Riyadh |
 | Louise Lombard als Lady Anne Davenport |
 | J.K. Simmons als Buffalo Bill Cody |
 | Adoni Maropis als Sakr |
 | Silas Carson als Katib |
 | C. Thomas Howell als Preston Webb |
 | Chris Owen als First Soldier |
 | Frank Collison als Texas Jack |
 | Victor Talmadge als Rau Rasmussen |
 | Adam Alexi-Malle als Aziz |
 | Harsh Nayyar als Yusef |
 | Joshua Wolf Coleman als The Kurd |
 | Saïd Taghmaoui als Prince Bin Al Reeh |
 | Peter Mensah als Jaffa |
 | Franky Mwangi als Slave Boy |
 | Floyd 'Red Crow' Westerman als Chief Eagle Horn |
 | Elizabeth Berridge als Annie Oakley |
 | Kimberly Guerrero als Frank's Mother |
 | Zac Badasci als Young Frank Hopkins |
 | Stevan Rimkus als Military Cistern Lieutenant |
 | Jerry Hardin als Nate Salisbury |
 | Marshall Manesh als Camel Skinner |
 | George Gerdes als Major Whitside |
 | Todd Kimsey als Corporal at Wounded Knee |
 | Malcolm McDowell als Major Davenport |
 | Mo Brings Plenty als Ghost Drummer |
| Joe Johnston | Director |
| John Fusco | Screenplay |
| Casey Silver | Producer |
| James Newton Howard | Original Music Composer |
| Shelly Johnson | Director of Photography |
| Robert Dalva | Editor |
| Nancy Foy | Casting |
| Barry Robison | Production Design |
| Jeffrey Kurland | Costume Design |
| Chris Salvaterra | Associate Producer |
| Don Zepfel | Executive Producer |
| Ahmed Abounouom | Art Direction |
| Kevin Constant | Art Direction |
| Troy Sizemore | Supervising Art Director |
| Garrett Lewis | Set Decoration |
| Abdellah Baadil | Art Department Assistant |
| Carol Kiefer | Art Department Coordinator |
| Patricio M. Farrell | Assistant Art Director |
| Douglas Womack | Construction Coordinator |
| Ronald S. Baratie | Greensman |
| Gary Isbell | Leadman |
| Jennifer Dunne | Location Scout |
| Dan Dorfer | Painter |
| Rodolfo Damaggio | Production Illustrator |
| Yann Denoual | Sculptor |
| Gregory S. Hooper | Set Designer |
| Chris Samp | Standby Painter |
| Jian Cong | Camera Technician |
| David Eubank | First Assistant Camera |
| Kamaleddine Talmi | Grip |
| Richard J. Cartwright | Still Photographer |
| Robert Wojewodski | Assistant Costume Designer |
| Carlane Passman | Costume Supervisor |
| Bunny Parker | Hair Department Head |
| Cheryl Eckert | Hairstylist |
| Nezha Aouis | Makeup Artist |
| Todd Masters | Prosthetic Supervisor |
| Corey Bronson | Set Costumer |
| Rob Grundy | Armorer |
| Frank Kilmartin | Carpenter |
| Richard Cody | Craft Service |
| Chris Arnold | Driver |
| Fouad Bourbouh | Loader |
| Myke Michaels | Makeup Effects |
| Angel Pine | Post Production Supervisor |
| Fred Apolito | Propmaker |
| Ken Deubel III | Scenic Artist |
| Alex Barnoya | Set Medic |
| Bruno Van Zeebroeck | Special Effects Coordinator |
| Katharine Chadwick | Stand In |
| Ricardo Cruz | Stunt Coordinator |
| Rachid Abbad | Stunts |
| Mustapha Ismaili Alaoui | Transportation Captain |
| Hicham Regragui | Transportation Coordinator |
| Christopher V. Bromley | Unit Production Manager |
| David Fulton | Unit Publicist |
| Dino Dos Santos | Utility Stunts |
| Youssef Mohattane | Video Assist Operator |
| David Tanaka | Visual Effects Editor |
| Brenda K. Wachel | Script Supervisor |
| Diva Magpayo | First Assistant Editor |
| Lyamani Bouhmdi | Best Boy Electric |
| Donald D. Davidson | Electrician |
| David Maddux | Gaffer |
| Timothy McCrary | Lighting Technician |
| Kenneth J. Appel | Rigging Gaffer |
| Jerry L. Marshall | Rigging Grip |
| Andrea Clark | Casting Associate |
| Mohamed Atbir | Location Manager |
| Tilly Creswell | Production Coordinator |
| Richard Luke Rothschild | Production Manager |
| Richard E. Chapla Jr. | Production Supervisor |
| Scott McKinstry | Researcher |
| David A. Smith | Boom Operator |
| Joseph Bonn | First Assistant Sound Editor |
| David Olson | Music Editor |
| Pete Anthony | Orchestrator |
| Mary H. Ellis | Production Sound Mixer |
| Shawn Murphy | Scoring Mixer |
| John Kwiatkowski | Sound Editor |
| Jason W. Jennings | Sound Effects Editor |
| David Parker | Sound Re-Recording Mixer |
| Howell Gibbens | Supervising Sound Editor |
| Sylvia Wong | Animation Supervisor |
| Chris Crowell | Digital Compositors |
| Peter Hutchinson | Special Effects Supervisor |
| Derek Ledbetter | Visual Effects |
| Damien Carr | Visual Effects Coordinator |
| Ginger Theisen | Visual Effects Producer |
| Tim Alexander | Visual Effects Supervisor |
| Oscar Delgadillo | Set Dresser |
| Hans Bjerno | Aerial Director of Photography |
| Yann Mari Faget | Second Assistant Director |
| Joe Dorn | ADR Supervisor |
| Daniel R. Bentley | Assistant Property Master |
| Antonio Tarolla | Draughtsman |
| Jim Leidholdt | Dolly Grip |
| Jack Taggart | Ager/Dyer |
| Shawna Trpcic | Costume Illustrator |
| Terry Anderson | Key Costumer |
| Michael Mills | Makeup Supervisor |
| Peter McKernan | Aerial Coordinator |
| Mark Forbes | Animal Coordinator |
| Burke Beardsley | Marine Coordinator |
| Daniel Griley | Techno Crane Operator |
| William M. Elvin | First Assistant Director |
| Tarik Ait Ben Ali | Third Assistant Director |
| Hamid Ait Timaghrit | Assistant Production Manager |
| Mohamed Essaghir Aabach | Casting Assistant |
| Matthew P. Hanson | Assistant Sound Editor |
| Bradford Harris | Musician |
| Aaron Martin | Music Programmer |
| Jim Weidman | Supervising Music Editor |
| Rick O'Connor | CG Animator |
| Jae Cheol Hong | Creature Technical Director |
| Beth D'Amato | Roto Supervisor |
| David Orr | Color Timer |
| James Ashwill | Foley Mixer |
| C.J. Maguire | Property Master |
| Lahcen Abbana | Costume Assistant |
| William A. Campbell | Costumer |
| Amina Ben Cherki | Hairdresser |
| Ruben Garcia | Second Second Assistant Director |
| Aziz Rafiq | Assistant Production Design |
| Jason Sweers | Graphic Designer |
| Fleur Nooyen | Set Buyer |
| Doc Kane | ADR Mixer |
| John T. Cucci | Foley Artist |
| Bud Raymond | Utility Sound |
| Ron Seigel | Special Effects Technician |
| Tonia Forsberg | Stunt Double |
| Michael B. Mullins | Assistant Camera |
| Danny Brazen | Best Boy Grip |
| John Conroy | Focus Puller |
| Chris Johnson | Second Assistant Camera |
| Zakia Essouci | Wardrobe Assistant |
| Tristan Barnard | Assistant Location Manager |
| Mustapha Adidou | Location Assistant |
| Pete Anthony | Conductor |
| Sophie Drouin | Accountant |
| Sandra Constantine | Assistant Accountant |
| Eddie Pasquarello | Compositing Supervisor |
| William Clay | Creature Technical Director |
| Kim Ju | Extras Casting |
| Anna Bradley | Extras Casting Assistant |
| Tiffany Fraser | First Assistant Accountant |
| Graeme Haughton | Generator Operator |
| Michael Neal | Payroll Accountant |
| Saad Ajedigue | Production Assistant |
| Hedy Phil Balani | Production Driver |
| Jinane Benzaida | Production Secretary |
| Sandra L. Dixon | Second Assistant Accountant |
| Bret Culpepper | Technical Advisor |
| Matt DiFranco | Travel Coordinator |
| Nick Foley | ADR Recordist |
| Alexander Witt | Second Unit Director |
| Patricia Carr | Co-Producer |
| James Logan | Stunts |
| Billy Joe Fredericks | Stunts |
| Heather Burton | Stunts |
| Dick Ziker | Stunts |
| Diana R. Lupo | Stunts |
| Troy Brown | Stunts |
| Freddie Hice | Stunts |
| Gregory J. Barnett | Stunts |
| Bevin Kaye | Utility Stunts |
| Pat Romano | Stunt Coordinator |
| Cinda-Lin James | Stunts |
| Casey O'Neill | Stunts |
| Henry Kingi Jr. | Stunts |
| Jan Bryant | Stunts |
| Jimmy Ortega | Utility Stunts |
