 | Kevin James als Scott Voss |
 | Salma Hayek Pinault als Bella Flores |
 | Henry Winkler als Marty Streb |
 | Greg Germann als Duke Betcher |
 | Joe Rogan als Joe Rogan |
 | Gary Valentine als Eric Voss |
 | Jake Zyrus als Malia De La Cruz |
 | Bas Rutten als Niko |
 | Nikki Tyler-Flynn als Mollie Streb |
 | Reggie Lee als Mr. De La Cruz |
 | Jason Miller als 'Lucky' Patrick Murphy |
 | Mark Muñoz als Romero |
 | Melissa Peterman als Lauren Voss |
 | Shelly Desai als Miguel |
 | Bruce Buffer als Bruce Buffer |
 | Krzysztof Soszynski als Ken 'The Executioner' Dietrich |
 | Satoshi Ishii als Fairgrounds Fighter |
 | Mark DellaGrotte als Mark DellaGrotte |
| Herb Dean als Herb Dean |
 | Arianny Celeste als Penelope 'Pinche Punisher' Lopez |
| Mookie Barker als Vice Principal Elkins |
| Mike Goldberg als Mike Goldberg |
 | Wanderlei Silva als Wanderlei Silva |
 | Chael Sonnen als Arguing Fighter |
 | Jacob 'Stitch' Duran als Jacob 'Stitch' Duran |
| Melchor Menor als Sityodtong Gym Fighter |
 | Lenny Clarke als Loud Dietrich Fan |
 | Jason Sandler als High School Student |
 | J. Michael Trautmann als Derrick |
 | Ivan Padilla als Martinez |
| Nicholas R. Grava als Jacob |
 | Frank Coraci als Disoriented Gym Patron |
 | Olivia Jordan als Ring Girl |
 | Rich Manley als Male Receptionist (uncredited) |
 | Jackie Flynn als Joe Duffy |
| Blaine Stevens als Mary Shannon Voss |
| Steven Ritchie als Brian |
 | Earnestine Phillips als Muba |
| Michael Burton als Ref at Fairgrounds |
 | Nicholas Turturro als Referee |
 | Ronald Boone als Fight Promoter (uncredited) |
 | Alex Ziwak als MMA Corner Man (uncredited) |
 | Deborah Rosencrans als Citizenship Student |
| Alan Au | Art Direction |
| Kevin James | Writer |
| Kevin James | Producer |
| Perry Andelin Blake | Production Design |
| Frank Coraci | Director |
| Marty P. Ewing | Executive Producer |
| Allan Loeb | Writer |
| Gino Falsetto | Production Office Assistant |
| Jeff Sussman | Producer |
| Justine Arteta | Casting |
| Mark Jan Wlodarkiewicz | Music Editor |
| Kim Davis-Wagner | Casting |
| Phil Meheux | Director of Photography |
| Rupert Gregson-Williams | Original Music Composer |
| Hope Hanafin | Costume Design |
| John S. Moyer | Steadicam Operator |
| Tracy Bennett | Still Photographer |
| Ronit Ravich-Boss | Script Supervisor |
| Katie Saunders | Costume Supervisor |
| Gary Jay | Camera Operator |
| Reagan Mendoza | Sound Re-Recording Mixer |
| Michael Hilkene | Supervising Sound Editor |
| Tateum Kohut | Sound Re-Recording Mixer |
| Garrett Warren | Stunt Coordinator |
| Fredrick Cuevas | Sound Re-Recording Mixer |
| Scott Hill | Editor |
| Greg Orloff | Sound Re-Recording Mixer |
| Angelo Palazzo | Sound Effects Editor |
| Odin Benitez | Supervising Sound Editor |
| John Jay Martyn | Sound Re-Recording Mixer |
| Ann Pala | Key Makeup Artist |
| Meg Bailey | Visual Effects Coordinator |
| Andrew Bell | Rigging Grip |
| Rebecca Woodfork | Hairstylist |
| Joseph Kearney | Construction Coordinator |
| Eric Komar | Dolly Grip |
| Jason Gourson | Assistant Editor |
| Alastair King | Orchestrator |
| Joel Reidy | Boom Operator |
| William Costello | Greensman |
| Hillary Derby | Key Costumer |
| Mark Fitzgerald | Location Manager |
| Carme Tenuta | Makeup Artist |
| Brad Hanyok | Carpenter |
| Mark J. Casey | Rigging Gaffer |
| Bill Trautvetter | Camera Operator |
| Joe Rossi | Makeup Artist |
| Scott Millette | Construction Coordinator |
| Brian Drewes | Visual Effects Producer |
| Paula Dion | Hairstylist |
| Jennifer Gerbino | Property Master |
| Daryl Richardson | Rigging Grip |
| Andre Dubois | Key Hair Stylist |
| Rocco Passionino | Visual Effects Supervisor |
| Peter D'Angelo | Rigging Grip |
| Jack McPhee | Best Boy Electric |
| Eric Harwood | Sound Recordist |
| Nathan Godley | Visual Effects Editor |
| Thomas Real | Key Hair Stylist |
| Carly Serodio | Art Department Coordinator |
| Darrell Pritchett | Special Effects Coordinator |
| Paul Taglianetti | Visual Effects Coordinator |
| Peter G. Travers | Visual Effects Supervisor |
| Georgia Pantazopoulos | Rigging Grip |
| Wally Webber | Rigging Grip |
| Todd Garner | Producer |
| Denise Pizzini | Set Decoration |
| Alexis Walker | Makeup Artist |
| Cameron Matheson | Leadman |
| Stephanie Lowry | Music Editor |
| Shari LaFranchi Blakney | Production Coordinator |
| Corina C. Duran-Rabichuk | Makeup Department Head |
| Larry Waggoner | Hair Department Head |
| Michael R. Blaich | Painter |
| Randall Guth | Foley |
| Scott D. Davis | Gaffer |
| Charles Harrington | Location Manager |
| Matthew W. Mungle | Makeup Effects Designer |
| K.C. Colwell | First Assistant Director |
| Christian Hejnal | Visual Effects Producer |
| Julia Smola | Visual Effects Coordinator |
| William M. Weberg | Key Grip |
| Carla Antonino | Makeup Artist |
| Anton Gold | Sound Mixer |
| Victoria Rose Sampson | Dialogue Editor |
| Jeremy Svenson | Production Assistant |
| Kurt Bryant | Stunts |
| Clay Cullen | Stunts |
| Garrett Warren | Second Unit Director |
| Steve Kelso | Stunt Driver |
