 | Leslie Nielsen als Mr. Quincy Magoo |
 | Kelly Lynch als Luanne LeSeur / Prunella Pegula |
 | Matt Keeslar als Waldo Magoo |
 | Nick Chinlund als Bob Morgan |
 | Stephen Tobolowsky als Agent FBI Chuck Stupak |
 | Ernie Hudson als Agent CIA Gus Anders |
 | Jennifer Garner als Stacey Sampanahoditra |
 | Malcolm McDowell als Austin Cloquet |
 | Miguel Ferrer als Ortega Peru |
 | L. Harvey Gold als Schmitt |
 | Art Irizawa als Gosha |
 | John Tierney als Hebzinski |
 | Terence Kelly als McManus |
 | Dolores Drake als Female Tourist |
 | Frank C. Turner als Ralston - Stage Manager |
| Monique Rusu als Rosita |
 | Robert Metcalfe als Desk Clerk |
 | Jerry Wasserman als Javier |
| Danny Steele als Tenor |
| Claire Riley als Newswoman |
| Stanley Tong | Director |
| Pat Proft | Screenplay |
| Tom Sherohman | Screenplay |
| Jingle Ma Choh-Sing | Director of Photography |
| David Rawlins | Editor |
| Stuart H. Pappé | Editor |
| Marcia Ross | Casting |
| Ben Myron | Producer |
| Justis Greene | Co-Producer |
| Greg Tiernan | Storyboard |
| Silvia Pompei | Animation |
| Rich Draper | Animation |
| Michael Tavera | Original Music Composer |
| Donna Morong | Casting |
| Michael R. Miller | Editor |
| Tom Bronson | Costume Design |
| John Willett | Production Design |
| Elizabeth Wilcox | Set Decoration |
| Doug Byggdin | Art Direction |
| Henry G. Saperstein | Executive Producer |
| Robert L. Rosen | Executive Producer |
| André E. Morgan | Executive Producer |
| Portia Tickell | Script Supervisor |
| Michael T. Ryan | Music Editor |
| Douglas Curran | Still Photographer |
| Douglas Craik | Camera Operator |
| Edmond Chan | Camera Operator |
| Rob Young | Production Sound Mixer |
| Tim Chau | Supervising Sound Editor |
| Tim Chau | Sound Designer |
| Donald J. Malouf | Sound Designer |
| Donald J. Malouf | Supervising Sound Editor |
| Mel Metcalfe | Sound Re-Recording Mixer |
| Terry Porter | Sound Re-Recording Mixer |
| Nils C. Jensen | Sound Effects Editor |
| David Kern | Sound Effects Editor |
| Angela O'Sullivan | Art Department Coordinator |
| Victoria Rose Sampson | Dialogue Editor |
| Jim Brookshire | Dialogue Editor |
| Brett Armstrong | Stunts |
| Owen Walstrom | Stunts |
| Lauro David Chartrand-DelValle | Stunts |
