 | Brad Pitt als John Smith |
 | Angelina Jolie als Jane Smith |
 | Vince Vaughn als Eddie |
 | Adam Brody als Benjamin Danz |
 | Kerry Washington als Jasmine |
 | Keith David als Father |
 | Chris Weitz als Martin Coleman |
 | Rachael Huntley als Suzy Coleman |
 | Michelle Monaghan als Gwen |
 | Stephanie March als Julie - Associate #1 |
 | Jennifer Morrison als Jade - Associate #2 |
 | Theresa Barrera als Janet - Associate #3 |
 | Perrey Reeves als Jessie - Associate #4 |
 | Melanie Tolbert als Jamie - Associate #5 |
 | Jerry T. Adams als Guard - Bull |
 | Elijah Alexander als Marco Racin |
| Hans F. Alexander als Louis |
| Lauryn Alvarez als Coleman Kid #2 |
| Burke Armstrong als Restaurant Patron |
 | Ron Bottitta als P.J. |
| Earl H. Bullock als 50's Man |
 | Miguel Angel Caballero als Bellboy - Bogotá |
 | Victor A. Chapa als Americana Hotel Manager |
 | Maree Cheatham als Father's Secretary |
 | Laine Collins als Eddie's Waitress |
| Noah Dahl als Coleman Kid #1 |
| Merrilee Dale als Mom #2 |
 | Chris Daniels als Mailman Assassin |
 | Patrika Darbo als 50's Woman |
 | Jennifer DeMille als Breakfast Diner Waitress |
 | Tyce Diorio als Salsa Dancer #2 |
| Patricia Donaldson als Louise |
 | Sabi Dorr als Bodyguard #3 |
 | Greg Ellis als Mickey |
| David Escobedo als Americana Hotel Bartender |
| Kaela Freeman als Neighborhood Girl |
 | Megan Gallagher als 40's Woman |
 | Amy Hathaway als Beauty |
| Jessica Hedden als Hopskotch Girl #2 |
| Kathrine Herzer als Hopscotch Girl #1 |
| Nigel Hudson als Boxing Sparring Partner |
 | Ravil Isyanov als Curtis |
 | Stephanie Ittleson als Party Guest |
 | Mark Ivanir als Patron - Dive Bar |
 | Benton Jennings als Maitre'D |
 | Simon Kinberg als Investment Banker #1 |
 | Peter Lavin als Leroy |
 | Deren Tadlock als Doorman |
 | Sean Mahon als Lucky |
 | Kevin Makely als Johnson |
| Mike McCaul als Bill the Neighbor |
| Derek Medina als Policia #2 |
| Will Moore als House Assassin #1 |
| Joel Munoz als Policia #1 |
| Mark Newsom als Guard #1 |
| Richie Ornelas als Policia #4 |
| Jordan Osher als House Assassin #2 |
 | Edward Padilla als Colombian Military Officer |
| Eugene C. Palmer als Judge |
| Luis Racer als Policia #3 |
 | Liz Ramos als Salsa Dancer #1 |
 | Leonard Robinson als Watchguard |
| Felix A. Ruiz als Vocalist |
 | Sam Sabbah als Bodyguard |
| Kim Schioldan als Bartender - Dive Bar |
| Ty Sharp als Towncar Driver |
 | Jimmy Shubert als Ancient Barker |
 | Abigail Rose Solomon als Mom #3 |
| Hannah Von Kanel als Hopskotch Girl #3 |
 | Ali Marsh als Mom #1 |
| Kim H. Winther als Mr. Smith's Father |
| Michael Winther als Investment Banker #2 |
 | Michael-John Wolfe als Bartender - Coleman House |
 | Jeff Yagher als 40's Man |
 | Bryan Anthony als Dancer |
| Douglas Caldwell als Dancer |
 | R.J. Durell als Dancer |
 | Melissa Hurley als Dancer |
| Jacqui Landrum als Dancer |
 | Carol Mack als Dancer |
| Michael Morris als Dancer |
| Gloria Rodriguez als Dancer |
| Linda Kathleen Taylor als Dancer |
| Anne Vardanian als Dancer |
| Ara Vardanian als Dancer |
| Luis Vasquez als Dancer |
| John W. Woodruff als Dancer |
 | Angela Bassett als Mr. Smith's Boss (voice) (uncredited) |
 | William Fichtner als Dr. Wexler - Marriage Counselor (voice) (uncredited) |
| David Block als Security Guard (uncredited) |
| John Branch als Swat Team Member (uncredited) |
 | Julius Callahan als Sebastian James (uncredited) |
| Shilo Frontierro als Assassin (uncredited) |
| Lisa Gabriel als Dancer (uncredited) |
 | Tony Longo als Big Bad Bathroom Dude (uncredited) |
 | Janelle Marra als Woman #3 (uncredited) |
 | Heather Petrone als BB Gun Shooter (uncredited) |
| Bill Viney als Dancer (uncredited) |
| Hawk Younkins als Swat Officer (uncredited) |
 | Matt McColm als Assassin (uncredited) |
 | Mo Gallini als Algerian Assassin (uncredited) |
| Michael Tronick | Editor |
| Joseph Middleton | Casting |
| John Powell | Original Music Composer |
| Erik Feig | Executive Producer |
| Doug Liman | Director |
| Patrick Wachsberger | Producer |
| Jeff Mann | Production Design |
| Akiva Goldsman | Producer |
| Keith Neely | Art Direction |
| Victor J. Zolfo | Set Decoration |
| Lucas Foster | Producer |
| Michael Kaplan | Costume Design |
| Simon Kinberg | Screenplay |
| Eric McLeod | Producer |
| Arnon Milchan | Producer |
| Bojan Bazelli | Director of Photography |
| Michelle Morris | Casting |
| Giovanni Lovatelli | Line Producer |
| Lori A. Balton | Location Scout |
| Richard Brooks Burton | Aerial Camera |
| Shawn Murphy | Scoring Mixer |
| Peter Dydo | 3D Artist |
| Kenji Luster | Steadicam Operator |
| B.J. Rogers | Assistant Costume Designer |
| Linda Matthews | Costume Supervisor |
| Julianne Jordan | Music Supervisor |
| Chuck Michael | Sound Editor |
| Jeri Baker | Key Hair Stylist |
| Randy L. Childs | Propmaker |
| Chris Daniels | Stunts |
| Darcy Reno | Systems Administrators & Support |
| Mark Soucie | Best Boy Electric |
| Cameron Frankley | Sound Designer |
| Paul Griffin | Animation Supervisor |
| Larry J. Aube | Key Grip |
| Matthew J. Barden | Grip |
| David R. Blakely | Driver |
| Mark Behar | Security |
| Simon Crane | Stunt Coordinator |
| David 'Goldy' Goldsmith | Video Assist Operator |
| Thomas A. Carlson | Music Editor |
| Mike Reichman | Art Department Assistant |
| Michael A. Clark | Carpenter |
| Damon Caro | Fight Choreographer |
| Rich Bennetti | Picture Car Coordinator |
| Michael Meinardus | Special Effects Coordinator |
| Patrick Flanagan | Digital Compositors |
| Steven Kemper | Additional Editing |
| Kim H. Winther | Co-Producer |
| Deborah La Mia Denaver | Makeup Department Head |
| Jaimie Linn | Stand In |
| Pamela Alch | Script Supervisor |
| Jason Andrew | Rigging Grip |
| John Cefalu | Location Manager |
| Jason W. Jennings | Sound Effects Editor |
| Chris Del Conte | Visual Effects Producer |
| Ronald S. Baratie | Greensman |
| Michael Bender | Painter |
| Beth Miller | Hair Department Head |
| Mark Shoaf | CG Supervisor |
| Ryan Juggler | Assistant Sound Editor |
| Ellyn Exley | Associate Producer |
| Dominic Aluisi | First Assistant Camera |
| Karl J. Weschta | Armorer |
| David Sandefur | Supervising Art Director |
| Lisa D. DiSanto | Art Department Coordinator |
| Lonnie A. Mathes | Post Production Assistant |
| Michael Tinger | Post Production Supervisor |
| Ryan Bonner | Set Production Assistant |
| Jonas Kirk | Construction Coordinator |
| Jamie Rama | Production Illustrator |
| Dawn Brown | Set Designer |
| P. Scott Bailey | Set Dressing Artist |
| Andrew B. Horton | Lighting Technician |
| Alessandro Fiorito | Production Accountant |
| Ralph Bertelle | Production Coordinator |
| Val Drake | Sculptor |
| Kent Harvey | Additional Camera |
| Lisa Buono | Makeup Artist |
| John Garrett | Loader |
| Jack Stern | Studio Teachers |
| David M. Milstien | Leadman |
| Steven Melton | Property Master |
| Kelly Kiernan | Unit Production Manager |
| Kim H. Winther | First Assistant Director |
| Steve Cantamessa | Sound Mixer |
| Ginger Damon | Hairstylist |
| Raymond Bulinski | Craft Service |
| Roger Bojarski Jr. | Transportation Captain |
| Desi Ortiz | Visual Effects Editor |
| Diane L. Sabatini | Production Supervisor |
| Mark Weber | Construction Foreman |
| Mark Blaydes | Set Medic |
| Billy G. Arter | Transportation Coordinator |
| Dana Arnold | Rigging Gaffer |
| Krista Allain | Visual Effects Coordinator |
| Kevin Elam | Visual Effects Supervisor |
| Varina Bleil | Associate Producer |
| Charles Kern | Standby Painter |
| Daniel Moder | Camera Operator |
| Stephen Vaughan | Still Photographer |
| Lauren Grey | Casting Associate |
| Michael Kirylo | Visual Effects |
| Greg Berry | Assistant Art Director |
| Toby Bronson | Set Costumer |
| David V. Butler | Dialogue Editor |
| Kevin Barrera | Electrician |
| Gary Thomas | Boom Operator |
| Brad Dechter | Orchestrator |
| Randall D. Wilkins | Set Designer |
| Tim Rigby | Utility Stunts |
| Tad Griffith | Utility Stunts |
| Michael Hansen | Utility Stunts |
| Laura Albert | Utility Stunts |
| Robert Consing | Storyboard Artist |
| David Betancourt | Foley Mixer |
| Anthony Kramer | Visual Effects Production Assistant |
| Craig Kohtala | Best Boy Grip |
| Aaron Brock | Assistant Editor |
| Grace Yim | Costume Assistant |
| Garnet Baril | Special Effects Assistant |
| S.R. Conger | Assistant Accountant |
| Erik Bruhwiler | Digital Compositor |
| Julio Salazar | Production Driver |
| Melanie Tolbert | Stunt Driver |
| Mo Henry | Negative Cutter |
| Matthew Evan Walsh | Post Production Coordinator |
| Ron Wisnesky | Assistant Chief Lighting Technician |
| Merrilee Dale | First Assistant Accountant |
| William A. Campbell | Key Costumer |
| Alexx Thompson | Set Painter |
| Jon Michaels | First Assistant Sound Editor |
| Kimberly Harris | Supervising ADR Editor |
| Dennis McHugh | VFX Director of Photography |
| Jeannie H. Kelly | Costumer |
| Michael Hansen | Assistant Property Master |
| Ulrika Akander | Supervising Dialogue Editor |
| Bart Barber | Special Effects Technician |
| Laura Graham | ADR Editor |
| Simon Crane | Second Unit Director |
| Howard London | ADR Mixer |
| David E. Scott | Graphic Designer |
| Jason Lanier Brown | VFX Artist |
| Michael Struk | Visual Effects Assistant Editor |
| Jaimarie Bjorge | Stunt Double |
| Leandro Visconti | Compositing Supervisor |
| Brad Combs | Executive Assistant |
| Wes Denton | Production Assistant |
| Jeff Barnes | Production Executive |
| Carrie Holecek | Digital Intermediate Producer |
| Ashley Kravitz | Clearances Coordinator |
| Gary Kangrga | Key Rigging Grip |
| Peter McKernan | Pilot |
| Tatjana Bozinovski | Rotoscoping Artist |
| John Bonnin | Libra Head Technician |
| Marguerite Pomerhn Derricks | Choreographer |
| Oscar J. Flores | Production Secretary |
| Mark Connelly | Second Assistant Camera |
| Ron Barr | Digital Intermediate Editor |
| Angela Randazzo | Payroll Accountant |
| Sean Lawrence | Colorist |
| Jason Columbus | Assistant Production Coordinator |
| Philip Huffman | Casting Assistant |
| Mark Watters | Conductor |
| Jojo Villanueva | Music Coordinator |
| Terri Greening | Accountant |
| Jerry Lee | Second Assistant Accountant |
| Dawn Fintor | Foley Artist |
| Joseph DiValerio | Visual Effects Designer |
| Matthew Mebane | Camera Loader |
| David Lucarelli | ADR Recordist |
| Michael Fucci | Assistant Location Manager |
| Mimi N. McGreal | Travel Coordinator |
| Kip Myers | Location Assistant |
| Ray Scalice | General Manager |
| Ron Crabb | Matte Painter |
| Sean Looper | Pipeline Technical Director |
| Stephen P. Del Prete | Second Second Assistant Director |
| Kent Demaine | Creative Director |
| Kristiona Arnds | Assistant Camera |
| Nico Bally | Dolly Grip |
| Barbara Harris | ADR Voice Casting |
| Jennifer Bender | Extras Casting |
| Brad Martin | Utility Stunts |
| Candice Carella | Costumer |
| Melissa R. Stubbs | Stunt Double |
| Karin Silvestri | Stunt Double |
| Anita Hart | Stunt Double |
| Boni Yanagisawa | Utility Stunts |
| Danny Wynands | Utility Stunts |
| Scott Workman | Utility Stunts |
| Darlene Ava Williams | Utility Stunts |
| Michael Weis | Utility Stunts |
| Shelly Ward | Utility Stunts |
| Aaron Walters | Utility Stunts |
| Jim Vickers | Utility Stunts |
| Jon Valera | Utility Stunts |
| Christopher J. Tuck | Utility Stunts |
| Tim Trella | Stunt Coordinator |
| Keith Tellez | Utility Stunts |
| Richard C. Taylor | Utility Stunts |
| Melissa R. Stubbs | Utility Stunts |
| Mark Stefanich | Utility Stunts |
| Chad Stahelski | Utility Stunts |
| Doug Snively | Utility Stunts |
| Gunter Simon | Utility Stunts |
| Karin Silvestri | Utility Stunts |
| Rick Shuster | Utility Stunts |
| Hashem Shaalan | Utility Stunts |
| Myke Schwartz | Stunts |
| David Schultz | Utility Stunts |
| Todd Schneider | Utility Stunts |
| James Ryan | Utility Stunts |
| Michael Runyard | Utility Stunts |
| Debbie Lynn Ross | Utility Stunts |
| Jason Rodriguez | Utility Stunts |
| Mic Rodgers | Stunt Coordinator |
| Troy Robinson | Utility Stunts |
| Shawn Robinson | Utility Stunts |
| Robby Robinson | Utility Stunts |
| Mario Roberts | Utility Stunts |
| Buster Reeves | Utility Stunts |
| Rex Reddick | Utility Stunts |
| Darrin Prescott | Utility Stunts |
| David Powledge | Utility Stunts |
| Jeff Podgurski | Utility Stunts |
| Gábor Piroch | Utility Stunts |
| Monte Rex Perlin | Utility Stunts |
| Chris Palermo | Utility Stunts |
| Jimmy Ortega | Utility Stunts |
| Casey O'Neill | Utility Stunts |
| Douglas Neithercut | Utility Stunts |
| Jack Moore | Utility Stunts |
| Heidi Moneymaker | Utility Stunts |
| Rick Miller | Utility Stunts |
| Rhys Millen | Utility Stunts |
| John C. Meier | Utility Stunts |
| Ed McDermott II | Stunt Driver |
| Matt McColm | Utility Stunts |
| Meredith Majors | Utility Stunts |
| Bob MacDougall | Utility Stunts |
| Dana C. Lynch | Utility Stunts |
| Billy D. Lucas | Utility Stunts |
| Michael Li | Utility Stunts |
| David Leitch | Stunt Double |
| Oakley Lehman | Utility Stunts |
| Gene LeBell | Utility Stunts |
| Samuel Le | Utility Stunts |
| Kevin LaRosa | Utility Stunts |
| Kevin LaRosa Jr. | Utility Stunts |
| Shawn Patrick Lane | Utility Stunts |
| Paul M. Lane | Utility Stunts |
| Theo Kypri | Utility Stunts |
| Mark Kubr | Utility Stunts |
| Joel Kramer | Utility Stunts |
| Ralf Koch | Utility Stunts |
| Dorian Kingi | Stunts |
| Henry Kingi Jr. | Utility Stunts |
| Shawn Kautz | Utility Stunts |
| Mike Justus | Utility Stunts |
| Brandon Johnson | Utility Stunts |
| Terry Jackson | Utility Stunts |
| Jeff Imada | Utility Stunts |
| Eunice Huthart | Stunt Double |
| David Hugghins | Utility Stunts |
| Tommy J. Huff | Utility Stunts |
| Toby Holguin | Utility Stunts |
| Freddie Hice | Utility Stunts |
| Nick Hermz | Utility Stunts |
| Alisa Hensley | Utility Stunts |
| Gene Hartline | Stunts |
| Gene Hartline | Utility Stunts |
| Anita Hart | Utility Stunts |
| Greg Harris | Utility Stunts |
| Tom Harper | Utility Stunts |
| Thomas Robinson Harper | Utility Stunts |
| James M. Halty | Utility Stunts |
| Charles Grisham | Utility Stunts |
| Steven Graves | Utility Stunts |
| Sean Graham | Stunt Double |
| Marvin Graham | Utility Stunts |
| Mickey Giacomazzi | Utility Stunts |
| Duffy Gaver | Utility Stunts |
| J. Armin Garza II | Utility Stunts |
| Christian J. Fletcher | Utility Stunts |
| Brent Fletcher | Utility Stunts |
| Debbie Evans | Utility Stunts |
| Corey Michael Eubanks | Utility Stunts |
| Richard Epper | Utility Stunts |
| Annie Ellis | Utility Stunts |
| Tom Elliott | Utility Stunts |
| Sandy East | Utility Stunts |
| Andy Dylan | Utility Stunts |
| Doc Duhame | Stunts |
| Doc Duhame | Utility Stunts |
| Dino Dos Santos | Utility Stunts |
| Mark De Alessandro | Utility Stunts |
| Tim A. Davison | Utility Stunts |
| Keith Splinter Davis | Utility Stunts |
| Jeffrey J. Dashnaw | Utility Stunts |
| Clay Cullen | Utility Stunts |
| Scott Cosgrove | Utility Stunts |
| Edward Conna | Utility Stunts |
| Norm Compton | Utility Stunts |
| Liisa Cohen | Stunt Double |
| Mark Chapman | Utility Stunts |
| Jacob Chambers | Utility Stunts |
| Richard Cetrone | Utility Stunts |
| David Castillo | Utility Stunts |
| Erin Carufel | Stunts |
| Jack Carpenter | Utility Stunts |
| Damon Caro | Utility Stunts |
| Troy Brown | Utility Stunts |
| Bob Brown | Utility Stunts |
| Eddie Braun | Utility Stunts |
| Kenny Bates | Utility Stunts |
| Stanton Barrett | Utility Stunts |
| Tammie Baird | Utility Stunts |
| Dean Bailey | Utility Stunts |
| Hank Amos | Utility Stunts |
| Wade Allen | Utility Stunts |
| Kenny Alexander | Utility Stunts |
| Vanessa White | Stunt Double |
| Mic Rodgers | Second Unit Director |
| Randal Johnson | Utility Stunts |
| Scott Waugh | Utility Stunts |
| Lisa Cohen | Utility Stunts |
