 | Megan Hilty als Patsy Cline |
 | Jessie Mueller als Loretta Lynn |
 | Kyle Schmid als Charlie Dick |
 | Janine Turner als Hilda Hensley |
 | Joe Tippett als Doolittle Lynn |
 | Billy Slaughter als Randy Hughes |
 | Justice Leak als Doyle Wilburn |
 | Jason Loughlin als Teddy Wilburn |
 | Jeremy Childs als Lamar Sneed |
 | Jane McNeill als Whiskey Soaked Lady |
 | Wynn Everett als Jeanette Davis |
 | Natalie Renee Long als Dottie West |
 | Erin Beute als June Carter |
| Jake Etheridge als Bill West |
| Hayden Blane als Blonde (uncredited) |
 | Cannon Bosarge als 13-Year-Old Jack Benny Lynn (uncredited) |
| Carla Bush als Background Guest (uncredited) |
| Emily Conley als Featured (uncredited) |
 | Johnny Counterfit als Announcer (uncredited) |
| Delaine Dobbs als Opry Musical Act (uncredited) |
 | Emma Duchesneau als 14-Year-Old Betty Sue Lynn (uncredited) |
| Virouna Elia als Honky Tonk Patron (uncredited) |
| Brian Scott Gilmore als Bartender (uncredited) |
 | Karen B. Greer als Hospital Visitor (uncredited) |
 | Garrett Kruithof als Delwood (uncredited) |
| Chelsea Lynn als Pregnant Woman (uncredited) |
 | John Michael Morris als Photographer (uncredited) |
 | Rosalyn R. Ross als Gertie (uncredited) |
| Walter Swierk als Agent (uncredited) |
 | Briana Tedesco als 10-Year-Old Cissy Lynn (uncredited) |
| Dave Tinsley als Hotel Guest (uncredited) |
| Amanda Torp als Hotel Guest (uncredited) |
| Robert Way als Honky Tonk Patron (uncredited) |
 | Alan Wells als DJ Ralph Emery (uncredited) |
| Jeffrey Wilkerson als Doctor (uncredited) |
| Hendley Williams als 10-Year-Old Betty Sue Lynn (uncredited) |
| Deb Yates als Ryman Attendee / Party Guest (uncredited) |
| Neil Meron | Executive Producer |
| Callie Khouri | Director |
| Angelina Burnett | Writer |
| Julie Fudge | Co-Producer |
| Mark Nicholson | Co-Executive Producer |
| Patsy Lynn Russell | Co-Producer |
| Susan Edelman | Casting Director |
| Tim Lauer | Original Music Composer |
| Scott Vickrey | Editor |
| Kendall Bennett | Production Design |
| Michael Lohmann | Director of Photography |
| Michael Lohmann | Producer |
| Callie Khouri | Executive Producer |
| Iddo Lampton Enochs Jr. | Unit Production Manager |
| Rick Kelly | First Assistant Director |
| Richard Welch | Second Assistant Director |
| Leigh Leverett | Costume Design |
| Tyler Sheldon | Set Decoration |
| Jim Diekhoff | Special Effects Coordinator |
| Jori Jenae | Makeup Department Head |
| Julie Callihan | Key Makeup Artist |
| Yvette Stone | Hair Department Head |
| Teresa Morgan | Key Hair Stylist |
| Kenny Barrickman | Post Producer |
| Fred Paragano | Supervising Sound Editor |
| Andrew Mayer | Supervising Sound Editor |
