 | Robert John Burke als Robocop |
 | Nancy Allen als Anne Lewis |
 | Rip Torn als The CEO |
 | John Castle als McDaggett |
 | Jill Hennessy als Dr. Marie Lazarus |
 | CCH Pounder als Bertha |
 | Mako als Kanemitsu |
 | Robert DoQui als Sergeant Reed |
 | Remy Ryan Hernandez als Nikko |
 | Bruce Locke als Otomo |
 | Stanley Anderson als Zack |
 | Stephen Root als Coontz |
 | Daniel von Bargen als Moreno |
 | Felton Perry als Johnson |
 | Bradley Whitford als Fleck |
 | Mario Machado als Casey Wong |
 | Jodi Long als Nikko's Mom |
 | John Posey als Nikko's Dad |
 | S.D. Nemeth als Bixby Snyder |
 | Edith Ivey als Elderly Woman in Bathrobe |
 | Curtis Taylor als Rehab #1 |
| Judson Vaughn als Seltz |
| Ken Strong als Rehab Patrol |
| Kenny Raskin als Security Monitor |
 | Blaise Corrigan als Officer at Ordnance Depot |
 | Jeff Garlin als Donut Jerk |
 | Lee Arenberg als Hold-Up Man |
| Randy Randolph als Cop in Donut Shop |
 | Shane Black als Donnelly |
| John Nesci als Jensen |
 | Randall Taylor als Starkweather |
 | James Lorinz als Upset Driver |
| Bryan Mercer als Splatterpunk #1 |
| Kenny Jones als Splatterpunk #2 |
 | Doug Yasuda als Kanemitsu's Aide |
 | Marc Gowan als Sleazy Lawyer |
| Thomas Boyd als Hooker |
| Eddie Billups als Man at Booking Desk |
| Gordon Mark als Techie in Robochamber |
 | Angie Bolling als Ellen Murphy |
| Graciela Marin als Cop with Body Armor |
| Michael H. Moss als Unfortunate Rehab |
| Dianne Butler als Woman on Vidphone |
 | David de Vries als Informative Yuppie |
 | Gary Bullock als Gas Station Clerk |
 | Wilbur Fitzgerald als Rebel with Weapons Cart |
| Beth Burns als Teen Prostitute |
 | Lonnie R. Smith Jr. als 1st Rehab at Hotel |
| Tommy Chappelle als Hotel Desk Clerk |
| Rick Seaman als Rehab Driver |
| Ron Leggett als Pimp |
 | Eva LaRue als Debbie Dix |
 | Alex Van als Rehab in War Room |
 | Jesse D. Goins als Joe P. Cox (archive footage) |
 | Kurtwood Smith als Clarence Boddicker (archive footage) |
 | Ray Wise als Leon Nash (archive footage) |
 | Paul McCrane als Emil M. Antonowsky (archive footage) |
 | Calvin Jung als Steve Minh (archive footage) |
| Fred Dekker | Director |
| Michael Miner | Characters |
| Patrick Crowley | Producer |
| Frank Miller | Screenplay |
| Steven Jacobs | Casting |
| Edward Neumeier | Characters |
| Fred Dekker | Screenplay |
| Bert Lovitt | Editor |
| Gary B. Kibbe | Director of Photography |
| Basil Poledouris | Original Music Composer |
| Jane Bartelme | Co-Producer |
| Frank Miller | Story |
| Andrew G. La Marca | Associate Producer |
| Phil Tippett | Visual Effects |
| Mike Johnson | Stunts |
| Steven Lambert | Stunts |
| Hilda Stark | Production Designer |
| Ha Nguyen | Costume Designer |
| Patrick Crowley | Unit Production Manager |
| Stephen J. Fisher | First Assistant Director |
| Thomas A. Irvine | First Assistant Director |
| John Wildermuth | Second Assistant Director |
| W. Alexander Ellis | Second Assistant Director |
| Dick Hancock | Stunt Coordinator |
| Russell Towery | Stunts |
| Michael Adams | Stunts |
| G. A. Aguilar | Stunts |
| Bruce Paul Barbour | Stunts |
| Davis Bates | Stunts |
| Dana Bertolette | Stunts |
| Richard L. Blackwell | Stunts |
| Eddie Braun | Stunts |
| Carl Ciarfalio | Stunts |
| Mark Chadwick | Stunts |
| George Cheung | Stunts |
| Tim Chitwood | Stunts |
| Roger Creed | Stunts |
| Blaise Corrigan | Stunts |
| Scott Dale | Stunts |
| Greg Wayne Elam | Stunts |
| Jeffrey Lee Gibson | Stunts |
| Tom Harper | Stunts |
| Diane Hoover | Stunts |
| Terry Jackson | Stunts |
| Shawn Patrick Lane | Stunts |
| Christopher Derek Lee | Stunts |
| Ben Loggins | Stunts |
| David Paul Lord | Stunts |
| Danny Mabry | Stunts |
| Anderson Martin | Stunts |
| Tim Moran | Stunts |
| Dean Mumford | Stunts |
| Christopher S. Nelson | Stunts |
| Jay Pearson | Stunts |
| Debbie Lynn Ross | Stunts |
| Bill M. Ryusaki | Stunts |
| Rick Seaman | Stunts |
| Tony Snegoff | Stunts |
| James Taenaka | Stunts |
| Adam Trammell | Stunts |
| Greg Walker | Stunts |
| Brian J. Williams | Stunts |
| Conrad E. Palmisano | Stunt Coordinator |
| Cate Bangs | Art Direction |
| Robert J. Franco | Set Decoration |
| Chris Shriver | First Assistant Art Direction |
| Bob Shaw | Assistant Set Decoration |
| Tom Warren | Assistant Art Director |
| Kate Sullivan | Assistant Art Director |
| Len Morganti | Storyboard Artist |
| Keith Tucker | Storyboard Artist |
| Jeff Jarvis | Special Effects Supervisor |
| Mike Reedy | Special Effects |
| Tim Moran | Special Effects |
| Kirk Francis | Sound Mixer |
| Alonzo Wilson | Costume Supervisor |
| Marciann Shapiro | Key Costumer |
| Chris Miller | Key Costumer |
| Kathryn Bihr | Key Makeup Artist |
| Sarah Mays | Assistant Makeup Artist |
| Emanuel Millar | Key Hair Stylist |
| Gail Hunter | Script Supervisor |
| Teresa M. Yarbrough | Production Coordinator |
| Katie Willard Troebs | Assistant Production Coordinator |
| Florent Danny Retz | Additional Editing |
| Yoko Seto | First Assistant Editor |
| Carol Folgate | Assistant Editor |
| Jeremiah O'Driscoll | Assistant Editor |
| Paul A. Levin | Post Production Supervisor |
| Kiki Morris | Post Production Supervisor |
| Jenifer Chatfield | Post Production Coordinator |
| Bruce Richardson | Supervising Sound Editor |
| Jay Kamen | Supervising ADR Editor |
| Victoria Rose Sampson | ADR Editor |
| Shelley Rae Hinton | ADR Editor |
| Scott Burrow | ADR Editor |
| John Haeny | Sound Effects Editor |
| Myron Nettinga | Sound Effects Editor |
| Julie Feiner | Dialogue Editor |
| Dave Kulczycki | Dialogue Editor |
| Larry Mann | Dialogue Editor |
| Marshall Winn | Dialogue Editor |
| Gary Wright | Dialogue Editor |
| Julie Feiner | Foley Editor |
| Dave Kulczycki | Foley Editor |
| Larry Mann | Foley Editor |
| Marshall Winn | Foley Editor |
| Gary Wright | Foley Editor |
| Eric Orlow | Assistant Sound Editor |
| Tom Villano | Music Editor |
| Weldon Brown | ADR Mixer |
| Paul J. Zydel | ADR Mixer |
| Debby de Gorter | ADR Recordist |
| Michael J. Cerone | ADR Recordist |
| Dean Drabin | Foley Mixer |
| Brian Ruberg | Foley Recordist |
| Maggie Murphy | Second Second Assistant Director |
| Evelyn D. Voight | Extras Casting |
| Conrad E. Palmisano | Second Unit Director |
| J. Tom Archuleta | Second Unit First Assistant Director |
| Frank M. Holgate | Second Unit Director of Photography |
| Maida N. Morgan | Second Unit Location Manager |
| Barbara Anne Klein | Stunts |
