 | Casey Kasem als Shaggy Rogers (voice) |
 | Don Messick als Scooby-Doo / Scrappy-Doo (voice) |
 | Rob Paulsen als Shreako / Dispatcher (voice) |
 | Ronnie Schell als Freako / Demonstrator Ghost (voice) |
 | Jerry Houser als Meako (voice) |
 | Sorrell Booke als Sheriff Rufus Buzby / T.J. Buzby (voice) |
 | Arte Johnson als Farquard / Skull Ghost (voice) |
 | William Callaway als Billy Bob Scroggins / Beaureguard / Horseman / Ape (voice) |
 | Victoria Carroll als Sadie Mae Scroggins (voice) |
 | Michael Rye als Mayor (voice) |
 | Hamilton Camp als Ghostly Laugh (uncredited voice) |
 | June Foray als Witch (uncredited voice) |
| Paul Sommer | Director |
| Carl Urbano | Director |
| Jim Ryan | Writer |
| Ray Patterson | Director |
| William Hanna | Executive Producer |
| Joseph Barbera | Executive Producer |
| Kay Wright | Producer |
| Robert Ciaglia | Editor |
| Gil Iverson | Editor |
| Andrea Romano | Casting |
| Jim Stenstrum | Character Designer |
| James T. Walker | Animation Director |
| Donna Zeller | Character Designer |
| Don Lusk | Animation |
| Bill Justice | Animation |
| Ray Patterson | Animation Director |
| Don Patterson | Animation Director |
| Sven Libaek | Original Music Composer |
| William Hanna | Songs |
