 | Christian Bale als John Connor |
 | Sam Worthington als Marcus Wright |
 | Moon Bloodgood als Blair Williams |
 | Helena Bonham Carter als Serena |
 | Anton Yelchin als Kyle Reese |
 | Common als Barnes |
 | Zach McGowan als Soldier on Osprey |
 | Bryce Dallas Howard als Kate Connor |
 | Jane Alexander als Virginia |
 | Michael Ironside als General Ashdown |
 | Ivan G'Vera als General Losenko |
 | Dorian Nkono als David |
 | Chris Browning als Morrison |
 | Beth Bailey als Lisa |
 | Victor J. Ho als Mark |
 | Buster Reeves als Tunney |
 | Jadagrace als Star |
 | Kevin Wiggins als General Olsen |
 | Greg Serano als Hideki |
 | Bruce McIntosh als Priest |
 | Po Chan als Naima |
 | Babak Tafti als Malik |
 | Treva Etienne als Len |
 | Michael Papajohn als Carnahan |
 | Dylan Kenin als Turnbull |
 | Chris Ashworth als Richter |
 | Diego Joaquin Lopez als Soilder |
| Greg Plitt als Hybrid Male |
 | Omar Paz Trujillo als Guard #2 |
 | Terry Crews als Captain Jericho |
 | Isaac Kappy als Barbarosa |
 | Boots Southerland als Warden |
 | David Midthunder als Soldier #1 |
| Rafael Herrera als Mexican Husband |
 | Maria Bethke als Mexican Wife |
| Marc Maurin als French Fighter |
 | Anjul Nigam als Rahul |
 | Emerson Brooks als First Soldier |
 | Lorenzo Callender als Comms Officer |
 | David Douglas als Technician |
 | Joe Basile als Radar Operator |
 | Esodie Geiger als Transmitter Technician |
 | Roland Kickinger als T-800 |
 | Brian Steele als T-600 Suit Performer |
 | Linda Hamilton als Sarah Connor (voice) (uncredited) |
 | Luke Kearney als Resistance Soldier (uncredited) |
 | Aaron Mastriani als Harvester Captive (uncredited) |
| Frank Powers als Resistance Fighter (uncredited) |
 | Mark Rayner als Helicopter Gunner (uncredited) |
| Chris Bentley als Execution Witness (uncredited) |
| Scott Flick als Skynet Prisoner (uncredited) |
| Neil Harbisson als Cyborg (uncredited) |
| Casey Wayne Hupp als Resistance fighter (uncredited) |
| Shani Klein-Madden als Execution Witness (uncredited) |
| Cynthia Lee als Harvester Captive (uncredited) |
| Gregory Leiker als Hardy (uncredited) |
 | Paul J. Porter als Infirmary Fighter (uncredited) |
| Scott Wyman als Driver (uncredited) |
| Foued Zayani als Skynet Prisoner (uncredited) |
 | John Gibbs als Harvester Captive (uncredited) |
| Martin Laing | Production Design |
| Danny Elfman | Original Music Composer |
| Moritz Borman | Producer |
| John Brancato | Writer |
| Michael Ferris | Writer |
| Troy Sizemore | Art Direction |
| McG | Director |
| Jeffrey Silver | Producer |
| Shane Hurlbut | Director of Photography |
| Conrad Buff IV | Editor |
| Victor Kubicek | Producer |
| Derek Anderson | Producer |
| Kim Davis-Wagner | Casting |
| Justine Arteta | Casting |
| Kimberly Greene | Makeup Department Head |
| Robert Q. Mathews | Costume Supervisor |
| Michael Wilkinson | Costume Design |
| Hugo Dominguez | Digital Effects Supervisor |
| Steven E. Gordon | Storyboard |
| Kathrine Gordon | Hair Department Head |
| Mark Ulano | Production Sound Mixer |
| Carol Kiefer | Art Department Coordinator |
| William Ballard | Transportation Coordinator |
| Jeanne Allgood | Executive Producer |
| Anjalika Mathur Nigam | Associate Producer |
| Don Zepfel | Associate Producer |
| Don Zepfel | Production Manager |
| Steve Gaub | Associate Producer |
| Roland N. Thai | Sound Effects Editor |
| Mario Kassar | Executive Producer |
| April A. Janow | Associate Producer |
| Trudy Ramirez | Script Supervisor |
| Doug Hemphill | Sound Re-Recording Mixer |
| Chris Moseley | Camera Operator |
| Ron Bartlett | Sound Re-Recording Mixer |
| Andrew G. Vajna | Executive Producer |
| Bruce Franklin | Associate Producer |
| Cameron Frankley | Supervising Sound Editor |
| Victor J. Zolfo | Set Decoration |
| Ai-Ling Lee | Sound Designer |
| George Billinger III | Steadicam Operator |
| Glenn Brown | First Assistant Camera |
| Dan Lin | Executive Producer |
| Joel B. Michaels | Executive Producer |
| Peter D. Graves | Executive Producer |
| Chantal Feghali | Co-Producer |
| Tom Struthers | Stunt Coordinator |
| Bill Abbott | Music Editor |
| Carole A. Kenneally | First Assistant Editor |
| Richard Foreman Jr. | Still Photographer |
| Lee Gilmore | Sound Effects Editor |
| Jason W. Jennings | Sound Designer |
| Cesar Angobaldo | Transportation Captain |
| Nadia Paine | Production Supervisor |
| John Walker | VFX Artist |
| Denise Gallo | Stunts |
| Deidre Parness | Makeup Artist |
| Betty Lou Skinner | Key Hair Stylist |
| Erin Wooldridge | Key Makeup Artist |
| Christopher Trujillo | Makeup Artist |
| Rolf John Keppler | Makeup Artist |
| Melissa Yonkey | Hair Department Head |
| Lisa Taylor Roberts | Makeup Department Head |
| Joy Zapata | Hair Department Head |
| Ed French | Makeup Artist |
| David V. Butler | Dialogue Editor |
| Stephen P. Dunn | First Assistant Director |
| Charles Gibson | Second Unit Director |
| Bryan Snodgrass | Second Second Assistant Director |
| Bruce Franklin | First Assistant Director |
| Zach Hunter | Second Second Assistant Director |
| Cyndi Martin | Second Second Assistant Director |
| Aimée Schaefer | Script Supervisor |
| Jeff Okabayashi | Second Assistant Director |
| Kathy McHugh | Script Supervisor |
| Adolfo Martínez Pérez | Additional Director of Photography |
| Paul Byrne Prenderville | Second Assistant Director |
| Katie Pruitt | Second Second Assistant Director |
| Lily García | Second Second Assistant Director |
| Stan Winston | Creature Effects Technical Director |
| Mark Hicks | Stunts |
| Mark Hicks | Stunt Double |
| Stan Winston | In Memory Of |
| Ben Snow | Visual Effects Supervisor |
| Susan Greenhow | Visual Effects Producer |
| Marc Chu | Animation Supervisor |
| Tom Hartig | Boom Operator |
| Michael Sexton | Property Master |
| Michael J. Burmeister | Location Manager |
| Freddy Waff | Leadman |
| Ann Foley | Assistant Costume Designer |
| Jacquelyn Palmquist | Casting Associate |
| Freya Krasnow | Casting Assistant |
| Lee Anne Muldoon | Unit Publicist |
| Bob Beher | Foley Editor |
| Thomas J. O'Connell | ADR Mixer |
| Troy Porter | ADR Mixer |
| Rick Canelli | ADR Recordist |
| Jason Oliver | ADR Recordist |
| Barbara Harris | ADR Voice Casting |
| John Roesch | Foley Artist |
| Alyson Dee Moore | Foley Artist |
| David Lee Fein | Foley Artist |
| Mary Jo Lang | Foley Mixer |
| Rick Wentworth | Conductor |
| Greg John Callas | Construction Coordinator |
| Christian Alzmann | Visual Effects Art Director |
| Jim Milton | Visual Effects Editor |
| Patrick Loungway | Second Unit Director of Photography |
| Andy Potvin | Dolby Consultant |
| Chantal Feghali | Visual Effects Producer |
| Dana Hee | Stunts |
| Ed Duran | Stunts |
| Kevin Black | Set Production Assistant |
| Angelique Midthunder | Stunts |
