 | Rob Schneider als Clive Maxtone/Jessica Spencer |
 | Rachel McAdams als Jessica Spencer/Clive Maxtone |
 | Anna Faris als April |
 | Matthew Lawrence als Billy |
 | Eric Christian Olsen als Jake |
 | Robert Davi als Stan |
 | Melora Hardin als Carol Spencer |
 | Alexandra Holden als Lulu |
 | Maritza Murray als Keecia |
 | Fay Hauser als Mrs. Thomas |
 | Jodi Long als Korean Mother |
 | Tia Mowry-Hardrict als Venetia |
 | Tamera Mowry-Housley als Sissy |
 | Lee Garlington als Vice Principal Bernard |
 | Angie Stone als Madame Mambuza |
| Matt Weinberg als Booger |
 | Leila Kenzle als Julie |
 | Michelle Branch als DJ |
 | Michael O'Keefe als Richie |
| Megan Kuhlmann als Hildenburg |
 | Ashlee Simpson als Monique |
 | Maria-Elena Laas als Bianca |
 | Adam Sandler als Mambuza Bongo Guy |
 | Katie Lohmann als Pole Cat Stripper |
| Scott Dolezal als Night Club Bartender |
 | Rebecca Lin als Palace Girl |
| Berglind Icey als Stripper |
 | Louis Lombardi als Pole Cat Bar Patron |
 | Teresa Espinosa als Hip Hop Freestyle Dancer |
 | Michael Papajohn als Security Guard |
| John Debney | Original Music Composer |
| Tim Suhrstedt | Director of Photography |
| Rob Schneider | Writer |
| John Hartigan | Special Effects Coordinator |
| Emjay Olson | Hairstylist |
| Jon Danniells | Set Decoration |
| Adam Sandler | Executive Producer |
| Jack Giarraputo | Executive Producer |
| Marc Fisichella | Production Design |
| Peck Prior | Editor |
| Marcia Ross | Casting |
| Guy Riedel | Executive Producer |
| Alix Friedberg | Costume Design |
| Peter Afterman | Music Supervisor |
| Sandy S. Solowitz | First Assistant Editor |
| Gail Goldberg | Casting |
| Kate Lacey | Casting Coordinator |
| Tom Brady | Director |
| Tom Brady | Writer |
| John Schneider | Producer |
| David Bach | Supervising Sound Editor |
| Corrina Duran | Makeup Artist |
| R. Michael Stringer | Rigging Grip |
| Christopher 'Critter' Antonucci | Stunt Double |
| Eric Reichardt | Scenic Artist |
| Marijane Cole | Stunts |
| Larry Waggoner | Hair Department Head |
| Udi Nedivi | Unit Production Manager |
| John P. Aguirre | Second Assistant Director |
| George Doering | Musician |
| Donna Morong | Casting |
| Bryan S. Sexton | Production Secretary |
| Kelly Moran-Brown | Production Coordinator |
| Ian Maxtone-Graham | Co-Producer |
| Keith Rogers | Sound Re-Recording Mixer |
| Tom Frohling | Art Direction |
| Tom Hartig | Boom Operator |
| Carme Tenuta | Key Makeup Artist |
| Dan DiPrima | Music Editor |
| Lisa Nichols | Studio Teachers |
| John C. Kruize | Production Accountant |
| Peggy Casey | Set Decoration Buyer |
| Clayton Weber | First Assistant Sound Editor |
| Ray McIntyre Jr. | Visual Effects Supervisor |
| Robert Jackson | Dialogue Editor |
| Monique Reymond | Foley Artist |
| James Lowder | Transportation Coordinator |
| Jeffrey Greeley | Camera Operator |
| Lawrence Karman | Steadicam Operator |
| Jim Moores | Picture Car Coordinator |
| Deborah Hall | Costume Supervisor |
| Mike Hardison | CG Supervisor |
| Cameron Steenhagen | ADR Editor |
| Reid Paul | Digital Effects Supervisor |
| Shane Reed | Leadman |
| Gregg Smrz | Stunt Coordinator |
| Gregg Smrz | Second Unit Director |
| Orada Jusatayanond | Sound Effects Editor |
| Rose Librizzi | Makeup Department Head |
| Tyra Youland | Ager/Dyer |
| Carr D'Angelo | Producer |
| Robin Mulcahy Fisichella | Associate Producer |
| Nathan Talbert Reimann | Co-Producer |
| Nicole Hilliard-Forde | Casting Associate |
| Cara Giallanza | First Assistant Director |
| Cesar Orozco | Propmaker |
| Chris Cuevas | Second Assistant Camera |
| Tony Gonzalez | Choreographer |
| Erich W. Schultz | Construction Coordinator |
| Jeff Smithwick | Color Timer |
| Mark Ulano | Production Sound Mixer |
| Max E. Brehme | Property Master |
| K.G. Ramsey | Key Hair Stylist |
| Deborah Simmrin | Unit Publicist |
| J. Armin Garza II | Driver |
| Frank Bennett | Orchestrator |
| Shane Buttle | Electrician |
| Angela Athayde | Production Assistant |
| Ivonne Olguin | Art Department Coordinator |
| Paulette Fox | Painter |
| James Van Houten | Sculptor |
| Camille M. Bratkowski | Set Designer |
| Mark Figueroa | First Assistant Camera |
| Darwin Montana Browne | Key Grip |
| Tim Fassino | Set Dresser |
| Michael D. Alvarez | Camera Loader |
| Alex Barnoya | Set Medic |
| Randolph Saucedo | Sound Recordist |
| Cashalà L'Shauntyelle | Stand In |
| Krister C. Johnson | Transportation Captain |
| Scott Crabbe | Video Assist Operator |
| Hope Garrison | Assistant Director |
| Julian Smirke | Editorial Production Assistant |
| Matt Bardocz | Best Boy Electric |
| Paul McIlvaine | Gaffer |
| John Bratlien | Lighting Technician |
| Brian Cantrell | Rigging Gaffer |
| Paul Schreiber | Location Manager |
| Josh Egnew | Sound Editor |
| Ralph Merzbach | 24 Frame Playback |
| Clay Dale | Visual Effects |
| Jana Spotts | Visual Effects Coordinator |
| Robin Richesson | Storyboard Artist |
| Nadia Aleyd | Casting Assistant |
| Bill Daimant | Dolly Grip |
| Scott W. Leslie | Assistant Property Master |
| Josh Denering | Grip |
| Christopher K. Grap | Assistant Production Coordinator |
| Adam Blantz | Utility Sound |
| Jessica Clements | Music Coordinator |
| Patrick Flanagan | Digital Compositor |
| Jeff Williams | Assistant Editor |
| David Yonson | ADR Recordist |
| Jim Stephan | Utility Stunts |
| Andrew Osborne | Assistant Camera |
| Celeste LaChance | Costumer |
| Mark Avery | Additional Second Assistant Director |
| Sharon Speller | Decorator |
| Jerry Miscevich | Special Effects Technician |
| Matt Evans | Post Production Coordinator |
| David Anthony | Extras Casting |
| Tiffany Fraser | First Assistant Accountant |
| Mark Vollmer | Key Rigging Grip |
| Timber Kislan | Payroll Accountant |
| Rudy Coblentz Jr. | Second Assistant Accountant |
