 | Keira Knightley als Domino Harvey |
 | Mickey Rourke als Ed Mosbey |
 | Edgar Ramírez als Choco |
 | Delroy Lindo als Claremont Williams |
 | Mo'Nique als Lateesha Rodriguez |
 | Christopher Walken als Mark Heiss |
 | Lucy Liu als Taryn Miles |
 | Mena Suvari als Kimmie |
 | Brian Austin Green als Self |
 | Ian Ziering als Self |
 | Macy Gray als Lashandra Davis |
 | Shondrella Avery als Lashindra Davis |
 | Riz Abbasi als Alf |
 | Dabney Coleman als Drake Bishop |
 | Joe Nuñez als Raul Chavez |
 | Peter Jacobson als Burke Beckett |
 | Kel O'Neill als Francis |
 | Jacqueline Bisset als Sophie Wynn |
 | Dale Dickey als Edna Fender |
 | Lew Temple als Locus Fender |
 | Liza Lapira als Chinegro Woman |
 | Tom Waits als Wanderer |
 | Jerry Springer als Self |
 | Tabitha Brownstone als Young Domino |
| Domino Harvey als Girl Walking from Exploding Car |
 | Charles Paraventi als Howie Stein |
 | Donna W. Scott als Agent Dina Wilson |
 | Michael Papajohn als Cigliutti Goon (uncredited) |
 | Vic Manni als Bishop Goon #1 |
 | T.K. Carter als Lester Kincaid |
 | Frederick Koehler als Chuckie |
 | Stanley Kamel als Anthony Cigliutti |
| Chad Parker als Underwater Mobster |
 | Cheryl Francis Harrington als Outraged Woman |
 | Ashley Monique Clark als Kee Kee Rodriguez |
 | Patrick Kerr als DMV Manager |
| Adam Clark als Agent Eric Cosgrove |
| Michael Andolini als Mobster |
| Janet Gonzalez als Louise Maldonado |
 | Mike G. als Hector Maldonado |
| Eddie Hernandez als Larenz 'Creep' Dexter |
| Mark Newsom als Dr. Waldman |
 | Jack McGee als Detective Chris Cudlitz |
 | Rolando Molina als Security Manager |
 | Morgan Nagler als Stacee Stevens |
| Ginger Kinison als Ariana Bower |
 | Andy Milder als FBI Agent #1 |
 | Neal Matarazzo als FBI Agent #2 |
| Michelle Fabiano als Mrs. Cigliutti |
| Phillip Darlington als Zendejas |
 | Celesta Hodge als Runway Model |
 | Julian Berlin als Sorority Girl |
 | Jackson Bolt als Bounty Hunter (uncredited) |
 | Heidi Hawking als Entertainer (uncredited) |
| Tony Scott | Director |
| Skip Chaisson | Executive Producer |
| Victor Hadida | Executive Producer |
| Tony Scott | Producer |
| Samuel Hadida | Producer |
| Lisa Ellzey | Executive Producer |
| Harry Gregson-Williams | Original Music Composer |
| Barry H. Waldman | Executive Producer |
| Denise Chamian | Casting |
| William Goldenberg | Editor |
| Drew Boughton | Art Direction |
| Zach Schiff-Abrams | Executive Producer |
| Keith Neely | Art Direction |
| Nancy Nye | Set Decoration |
| Dan Mindel | Director of Photography |
| Christian Wagner | Editor |
| Chris Seagers | Production Design |
| Toby Emmerich | Executive Producer |
| B. Åkerlund | Costume Design |
| Martin Samuel | Hairstylist |
| Lucia Mace | Hairstylist |
| Fiona Connon | Makeup Department Head |
| Karin Anderson | Script Coordinator |
| Julie Pitkanen | Script Supervisor |
| Dan Bell | Stunts |
| David Hadida | Co-Producer |
| Peter Toumasis | Co-Producer |
| Martin Samuel | Hair Department Head |
| Anthony Miner | Hairstylist |
| Luisa Abel | Key Makeup Artist |
| Amanda Fernald Jones | Art Department Assistant |
| Nithya Shrinivasan | Assistant Art Director |
| Dennis Richardson | Carpenter |
| David Harris | Greensman |
| Roderick Nunnally | Standby Painter |
| Mark Alfrey | Sculptor |
| Nancy Deren | Set Designer |
| Billy Campbell | Set Dresser |
| Chris Ingram | Assistant Sound Editor |
| Timothy P. Salmon | Boom Operator |
| Gloria D'Alessandro | Dialogue Editor |
| Andy Potvin | Dolby Consultant |
| Matthew Harrison | Foley Editor |
| Jeff Jingle | Animatronics Designer |
| David Dresher | Post Production Supervisor |
| Trevor Waterson | Production Supervisor |
| Barry H. Waldman | Unit Production Manager |
| Joe Pancake | Special Effects Coordinator |
| John Frazier | Special Effects Supervisor |
| Sean Andrew Faden | CG Supervisor |
| John Wildermuth | First Assistant Director |
| Mark Alan Loso | Compositor |
| Emma McGuinness | Executive Visual Effects Producer |
| Chuck Picerni Jr. | Stunt Coordinator |
| Christina Fong | Utility Stunts |
| Mark Meyers | Additional Camera |
| Richard Brooks Burton | Aerial Camera |
| David B. Nowell | Aerial Director of Photography |
| Christopher Prampin | Best Boy Electric |
| Stephanie Higgins Frey | Art Department Coordinator |
| Andy Bertelson | Grip |
| Chris Weigand | Lighting Technician |
| John R. Manocchia | Rigging Gaffer |
| Alan Downs | Rigging Grip |
| Maryellen Aviano | Extras Casting |
| Scout Masterson | Casting Associate |
| Jimmy Jay | Ager/Dyer |
| Matthew Goldman | Assistant Costume Designer |
| Dale DeStefani | Construction Coordinator |
| Joe Hathaway | Digital Color Timer |
| Claudius Neal | Digital Intermediate |
| Emile Hanton | Post Production Assistant |
| Lori A. Balton | Location Scout |
| Kim Carroll | Musician |
| Gil Amaral | Driver |
| Ron Kunecke | Transportation Captain |
| R. Scott Doran | Leadman |
| Michael Papac | Armorer |
| Elona Tsou | Production Coordinator |
| Mike Blaze | Property Master |
| Michael Aronson | Propmaker |
| T. Scott Elliott | Props |
| Jim Smith | Craft Service |
| Michael Barnes | Legal Services |
| Monica Rust | Set Medic |
| Cyril O'Neil | Picture Car Coordinator |
| Julie Hansen | Post Production Accountant |
| Donna Glasser-Hancock | Production Accountant |
| Michael Cosmano | Production Office Assistant |
| Katie Pruitt | Set Production Assistant |
| Randle Akerson | Sound Effects Editor |
| Art Rochester | Sound Mixer |
| Craig Mann | Sound Recordist |
| Casey Lowe | Stand In |
| Judith M. Brown | Studio Teacher |
| F. Hudson Miller | Supervising Sound Editor |
| Gabriela Gutentag | Unit Publicist |
| Sam Rockwell | Thanks |
| Michael Off | Gaffer |
| J. Michael Popovich | Key Grip |
| David Lai | Music Supervisor |
| Brandon M. Cox | Loader |
| Nathan McGuinness | Visual Effects Supervisor |
| Brian Berdan | Additional Editor |
| Ryan Meredith | Visual Effects Coordinator |
| Kosta Saric | Visual Effects Editor |
| Kirk Bennett | Orchestrator |
| Maya Evans Judd | Costumer |
| Annie Hill | Key Costumer |
| Kathy Chasen-Hay | Visual Effects Producer |
| Tom Callinicos | On Set Dresser |
| Eric Glasser | Additional Second Assistant Director |
| Christina Fong | Second Assistant Director |
| Marisa Ferrey | Second Second Assistant Director |
| Andres L. Porras | Camera Operator |
| Greg Etheredge | Electrician |
| Rick Chavez | Assistant Property Master |
| John T. Connor | First Assistant Camera |
| Wendy Drapanas | Graphic Designer |
| Frank Masi | Still Photographer |
| Melissa Pergola | Set Decorating Coordinator |
| Andrea Horta | ADR Editor |
| Colin Cooper | ADR Mixer |
| Rick Canelli | ADR Recordist |
| Bob Morgan | Costume Supervisor |
| David Dietch | Set Costumer |
| Dan O'Connell | Foley Artist |
| James Ashwill | Foley Mixer |
| Juno J. Ellis | Supervising ADR Editor |
| Lucy Coldsnow-Smith | Supervising Dialogue Editor |
| Cindy Braga | Special Effects Technician |
| Paul Luna | 2D Artist |
| Lisa Hoyle | Stunt Double |
| Janice Polley | Location Manager |
| Ed McDermott II | Stunt Driver |
| Richard Whitfield | Music Editor |
| Mariana Sánchez de Antuñano | Assistant Camera |
| Ray D. Chase | Best Boy Grip |
| Bryce Guy Williams | Transportation Coordinator |
| Hector Gutierrez | Dolly Grip |
| Steve Wolfe | Second Assistant "A" Camera |
| Michael T. Coruzzi | Second Assistant Camera |
| Angela Demo | Casting Assistant |
| dB Bracamontes | Additional Editing |
| Robert Berman | Assistant Editor |
| Gerald Ragland | Digital Intermediate Assistant |
| David Feldman | Digital Intermediate Producer |
| Skip Chaisson | Editorial Consultant |
| Betty Burkhart | Post Production Coordinator |
| Julie Hannum | Assistant Location Manager |
| Justin Duncan | Location Assistant |
| David Paris | Aerial Coordinator |
| Merrilee Dale | First Assistant Accountant |
| Dan Tipton | Assistant Production Coordinator |
| Andrea Paige Wilson | Choreographer |
| Tom Moran | Executive Assistant |
| Kari Mills | Extras Casting Assistant |
| Eric Glasser | Key Set Production Assistant |
| Joshua D. Thatcher | Lighting Programmer |
| Timothy Clark | Matte Painter |
| Brigitte Pauli | Payroll Accountant |
| David Calvert-Jones | Pilot |
| Braden Friedman | Production Assistant |
| Jason Salzman | Production Secretary |
| Corinne Fixmer | Second Assistant Accountant |
| René Brar | Story Editor |
| Gilda 'Granny' Granadino | Technical Advisor |
| Samuel Hadida | Presenter |
| Barbara Harris | ADR Voice Casting |
| Richard Kelly | Screenplay |
| Steve Barancik | Story |
| Richard Kelly | Story |
| Anita Hart | Stunts |
| Rob Hinderstein | Makeup Effects Designer |
| Joel Harlow | Makeup Effects Designer |
| Hunter Baxley | Stunts |
| Christopher 'Critter' Antonucci | Stunts |
| Freddy Bouciegues | Stunts |
| William H. Burton Jr. | Stunts |
| Jacob Chambers | Stunts |
| Cindy Daniels | Stunts |
| Norm Compton | Stunts |
| Preston Corbell | Stunts |
| Tim A. Davison | Stunts |
| Max Daniels | Stunts |
| Steve M. Davison | Stunts |
| Annie Ellis | Stunts |
| Richard Epper | Stunts |
| Jeff Evans | Stunts |
| Michael Endoso | Stunts |
| Brent Fletcher | Stunts |
| Frankie 'G' Garbutt | Stunts |
| Mitch Gould | Stunts |
| Troy Gilbert | Stunts |
| Tim Gilbert | Stunts |
| Tad Griffith | Stunts |
| Jeff Imada | Stunts |
| David LeBell | Stunts |
| James M. Halty | Stunts |
| Sammy Maloof | Stunts |
| Bof Matteo | Stunts |
| Randolph LeRoi | Stunts |
| Jeffrey McDancer | Stunts |
| Dan McCann | Stunts |
| Dustin Meier | Stunts |
| John C. Meier | Stunts |
| Don Charles McGovern | Stunts |
| Bennie Moore | Stunts |
| Marty Murray | Stunts |
| Julie Michaels | Stunts |
| Larry Nicholas | Stunts |
| Casey O'Neill | Stunts |
| Michael Owen | Stunts |
| Alan Oliney | Stunts |
| Vladimir Orlov | Stunts |
| J.J. Perry | Stunts |
| Chad Parker | Stunts |
| Michael Papajohn | Stunts |
| Steve Picerni | Stunts |
| William Rocha | Stunts |
| Jimmy N. Roberts | Stunts |
| Scotty Richards | Stunt Driver |
| Erik Rondell | Stunt Double |
| Pat Romano | Stunts |
| Danny Rogers | Stunts |
| Madison Saager | Stunt Double |
| Matthew Rugetti | Stunts |
| Lee Smith | Stunt Double |
| Paul Sklar | Stunts |
| Brian Simpson | Stunts |
| Justin Sundquist | Stunts |
| Buddy Sosthand | Stunts |
| Scott Wilder | Stunts |
| Marcus Young | Stunts |
| Garrett Warren | Stunt Double |
| Rex Reddick | Stunts |
| DJ Stefanich | Stunts |
| Philip Romano | Stunts |
| Eric Frazier | Special Effects |
