 | Chester Morris als Horatio 'Boston Blackie' Black |
 | Janis Carter als Dorothy Anderson |
 | William Wright als Paul Martens |
 | Richard Lane als Inspector Farraday |
 | George E. Stone als The Runt |
 | Robert B. Williams als Matt Healy |
 | Mark Roberts als George Daley |
 | Dorothy Malone als Eileen Daley (Uncredited) |
 | Joseph Crehan als Jumbo Madigan (Uncredited) |
 | Ben Taggart als Traffic Cop (Uncredited) |
 | Minerva Urecal als Miss Wilkinson (Uncredited) |
 | Constance Purdy als Woman in Daley's Office (Uncredited) |
 | Ed Allen als Policeman (Uncredited) |
 | Kenneth Brown als Boy (Uncredited) |
| Early Cantrell als Margaret Dean (Uncredited) |
| Lew Davis als Exhibit Attendee (Uncredited) |
| Edythe Elliott als Mother (Uncredited) |
| Jack Gardner als Frank (Uncredited) |
| Fred Graff als Reporter (Uncredited) |
| Harrison Greene als Arthur Manleder (Uncredited) |
| Fred Howard als Reporter (Uncredited) |
| Dick Jensen als Policeman (Uncredited) |
| Henry Jordan als Reporter (Uncredited) |
 | Edward Keane als Police Commissioner Howard (Uncredited) |
| Tom Kingston als News Photographer (Uncredited) |
 | Lyle Latell als Detective Sergeant Matthews (Uncredited) |
 | Billy Lenhart als Boy (Uncredited) |
| Anne Loos als Newsstand Clerk (Uncredited) |
 | George Magrill als Police Guard (Uncredited) |
| Cy Malis als Policeman (Uncredited) |
 | George McKay als Police Sergeant McNulty (Uncredited) |
 | Pat O'Malley als Police Sergeant (Uncredited) |
 | John Tyrrell als Austin (Uncredited) |
 | Bob Walker als Man in Office with Matthews (Uncredited) |
| Cecil Weston als Mother (Uncredited) |
| Ted Richmond | Producer |
| L. William O'Connell | Director of Photography |
| Al Clark | Editor |
| Budd Boetticher | Director |
| Paul Yawitz | Writer |
| Jack Boyle | Writer |
| Paul Sawtell | Original Music Composer |
| Lionel Banks | Art Direction |
| George Brooks | Art Direction |
| Robert Priestley | Set Decoration |
| Milton Feldman | Assistant Director |
| Lambert E. Day | Sound |
| Mischa Bakaleinikoff | Music Director |
| Werner R. Heymann | Additional Music |
| Earl E. Lawrence | Additional Music |
| Ben Oakland | Additional Music |
| Gregory Stone | Additional Music |
