 | Anthony Gonzalez als Miguel Rivera (voice) |
 | Gael García Bernal als Héctor (voice) |
 | Benjamin Bratt als Ernesto de la Cruz (voice) |
 | Alanna Ubach als Mamá Imelda Rivera (voice) |
 | Renée Victor als Elena Rivera (voice) |
 | Ana Ofelia Murguía als Mamá Socorro "Coco" Rivera (voice) |
 | Edward James Olmos als Chicharrón (voice) |
 | Jaime Camil als Papá Enrique Rivera (voice) |
 | Alfonso Arau als Papá Julio Rivera (voice) |
 | Herbert Siguenza als Tío Oscar Rivera / Tío Felipe Rivera (voice) |
 | Lombardo Boyar als Mariachi / Gustavo (voice) |
 | Sofía Espinosa als Mamá Luisa Rivera (voice) |
 | Dyana Ortelli als Tía Victoria Rivera (voice) |
 | Gabriel Iglesias als Head Clerk (voice) |
 | Selene Luna als Tía Rosita Rivera (voice) |
 | Natalia Cordova-Buckley als Frida Kahlo (voice) |
 | Carla Medina als Departure Agent (voice) |
 | Luis Valdez als Tío Berto Rivera / Don Hidalgo (voice) |
 | Blanca Araceli als Emcee (voice) |
| Polo Rojas als Abel Rivera (voice) |
 | Montse Hernandez als Rosa Rivera (voice) |
| Octavio Solis als Arrival Agent (voice) |
 | Cheech Marin als Corrections Officer (voice) |
| Salvador Reyes als Security Guard (voice) |
 | John Ratzenberger als Juan Ortodoncia (voice) |
 | Daniel Edward Mora als Additional Voices (voice) |
| Lee Unkrich | Director |
| Harley Jessup | Production Design |
| Adrian Molina | Co-Director |
| Adrian Molina | Screenplay |
| Matthew Aldrich | Screenplay |
| Darla K. Anderson | Producer |
| Mary Alice Drumm | Associate Producer |
| Matt Aspbury | Director of Photography |
| Danielle Feinberg | Director of Photography |
| John Lasseter | Executive Producer |
| Lee Unkrich | Editor |
| Michael Giacchino | Original Music Composer |
| David Torres | Animation |
| Courtney Casper Kent | Art Department Manager |
| Aaron Koressel | Animation |
| Shaun Chacko | Animation |
| Dionys Heurtel | Animation |
| Matthew Strangio | Animation |
| Royce Wesley | Animation |
| Alonso Martinez | Character Designer |
| Meghan Kraft | Additional Editorial Assistant |
| Adam Rodriguez | Animation |
| K. C. Roeyer | Animation |
| Raphael Suter | Animation |
| Natalie Lyon | Casting |
| Anna Wolitzky | Additional Editing |
| Terri Douglas | ADR Voice Casting |
| Mike Stern | Animation |
| Tony Fucile | Character Designer |
| Greg Dykstra | Character Designer |
| Carla Hool | Casting |
| Jesus Martinez | Animation Manager |
| Cody Lyon | Animation |
| Michael Sauls | Animation |
| Daniel Lopez Muсoz | Character Designer |
| Shad Bradbury | Animation |
| Zaruhi Galstyan | Character Designer |
| Jessica Torres | Animation |
| Don Crum | Animation |
| Ben Rush | Animation |
| Tim Evatt | Art Direction |
| Andrew Atteberry | Animation |
| Simon Christen | Animation |
| Joshua Dai | Animation |
| Jayson Price | Animation |
| Catherine Hang-Hicks | Animation |
| Nicole Ridgwell | Animation |
| Daniel Arriaga | Character Designer |
| Kevin Reher | Casting |
| Michael Bidinger | Animation |
| Paul Diaz | Animation |
| Lance Fite | Animation |
| Andrew Gonzalez | Animation |
| Charles Larrieu | Animation |
| Guillaume Chartier | Animation |
| Bruce Kuei | Animation |
| Benjamin Su | Animation |
| Carter Goodrich | Character Designer |
| Sarah K. Reimers | Additional Editorial Assistant |
| Frank E. Abney III | Animation |
| Amanda Wagner | Animation |
| J.D. Aguilar | Conductor |
| Youri Dekker | Fix Animator |
| George Doering | Musician |
| Michael Venturini | Supervising Animator |
| Germaine Franco | Songs |
| Marshall Winn | Dialogue Editor |
| Jessica Katz | Editorial Coordinator |
| Freddie Sulit | Editorial Coordinator |
| Luis Carlos Uribe | Fix Animator |
| Dorien Gunnels | Lighting Artist |
| Farhez Rayani | Lighting Artist |
| Tim Best | Lighting Supervisor |
| Germaine Franco | Additional Soundtrack |
| Tom MacDougall | Music Supervisor |
| Gates Roberg-Clark | Software Engineer |
| BoB 'Naked BoB' Morgan | Systems Administrators & Support |
| John Henry Frankenhauser | Systems Administrators & Support |
| Jonathan Pytko | Visual Effects |
| David Ryu | Visual Effects |
| Daniela Strijleva | Character Designer |
| Germaine Franco | Orchestrator |
| Burt Peng | Lighting Artist |
| Shaun Galinak | VFX Artist |
| Geoff Vaughan | Foley |
| Luis David Reyes Reyes | Music Supervisor |
| Antonio Sol | Playback Singer |
| Maura Turner | Production Office Assistant |
| Baraka May | Musician |
| Tiffany Taira | Archival Footage Research |
| Bruce White | Musician |
| Doc Kane | ADR & Dubbing |
| Adrian Bell | Software Engineer |
| Shawn Hovis | Systems Administrators & Support |
| Emron Grover | Visual Effects |
| Philip Shoebottom | Master Lighting Artist |
| Jana Vance | Foley |
| Jim Likowski | Foley Editor |
| Mimia Arbelaez | Lighting Artist |
| Stephen M. Davis | Music Editor |
| Kristen Anderson-Lopez | Songs |
| Collin Allen | Systems Administrators & Support |
| Michael Frederickson | Visual Effects |
| Michael O'Brien | Visual Effects Supervisor |
| Sam Kriger | Vocal Coach |
| Dee Selby | Foley Editor |
| Dan Berman | Systems Administrators & Support |
| Ling Hsu | Systems Administrators & Support |
| Jamie Hecker | Visual Effects |
| Lucas Miller | Sound Design Assistant |
| Nic Bishop | Systems Administrators & Support |
| Aaron Conover | Visual Effects |
| Stephen Matthew Gustafson | Visual Effects |
| Max Sachar | Editorial Manager |
| Teresa Eckton | Foley Editor |
| Ken Lao | Master Lighting Artist |
| Greg Snyder | Second Film Editor |
| Justin Doyle | Sound Effects Editor |
| Teresa Conaty | Systems Administrators & Support |
| Erik Shepherd | VFX Artist |
| Carolina Ángel | Production Coordinator |
| Krissy Cababa | Editorial Manager |
| Teresa Eckton | Sound Effects Editor |
| Maria Dominique Lopez | Musician |
| Joel Iwataki | Scoring Mixer |
| Tim Fox | Second Film Editor |
| Alison Leaf | Set Dressing Artist |
| Gini Cruz Santos | Supervising Animator |
| Shaun Brown | Systems Administrators & Support |
| Dave Strick | Visual Effects |
| Michael Silvers | Dialogue Editor |
| Lisa Fotheringham | Lighting Manager |
| Michael Semanick | Sound Re-Recording Mixer |
| Mike H. Mahony | Software Engineer |
| J.R. Grubbs | Supervising Sound Editor |
| Kristopher Campbell | Visual Effects |
| Michael Honsel | Visual Effects |
| Chris Bolwyn | VFX Artist |
| Marshall Bowen | Conductor |
| Federico Ramos | Musician |
| Jeff Kryka | Orchestrator |
| Amy L. Allen | Lead Set Dresser |
| Jack Whittaker | Sound Effects Editor |
| Susanne Rublein | Systems Administrators & Support |
| Tyler Bay | VFX Artist |
| Jennifer Neysa Jew | First Assistant Editor |
| Linhan Li | Lighting Artist |
| Charu Clark | Master Lighting Artist |
| Jordan Rempel | Master Lighting Artist |
| Christopher Boyes | Sound Designer |
| Andy Thomas | Systems Administrators & Support |
| Jonathan Hoffman | Visual Effects |
| Lisa Chino | First Assistant Sound Editor |
| Michael Miller | ADR & Dubbing |
| Robert Lopez | Songs |
| Christopher Boyes | Sound Re-Recording Mixer |
| Jonathan Hadden | Systems Administrators & Support |
| Dennie Thorpe | Foley |
| Blake Collins | Foley |
| Jose Luis Ramos | Master Lighting Artist |
| Warren Brown | Music Editor |
| Félix O. Santiago | Software Engineer |
| Andrew Synowiec | Musician |
| Dana Frankoff | Production Coordinator |
| David Park | Production Manager |
| Daryn Cash | Systems Administrators & Support |
| Don Shank | Set Designer |
| Steve Bloom | Editor |
| Vladimir Kooperman | Story Artist |
| Tony Maki | Story Artist |
| Rachael Bigelow | Additional Production Sound Mixer |
| Jason Johnston | VFX Artist |
| Jamie Williams | Visual Effects Technical Director |
| Becky Neiman | Thanks |
| Seong-Young Kim | Layout |
| Hikari Toriumi | Animation |
| Madeline Sharafian | Story Artist |
| Lee Unkrich | Original Story |
| Adrian Molina | Original Story |
| Jason Katz | Original Story |
| Matthew Aldrich | Original Story |
| Kenny Pickett | Sound |
| Nathaniel McLaughlin | Art Direction |
| Enrico Casarosa | Story Artist |
