 | Jude Law als Sky Captain |
 | Gwyneth Paltrow als Polly Perkins |
 | Angelina Jolie als Franky |
 | Giovanni Ribisi als Dex |
 | Michael Gambon als Paley |
 | Bai Ling als Mysterious Woman |
 | Omid Djalili als Kaji |
 | Laurence Olivier als Dr. Totenkopf (archive footage) |
 | Trevor Baxter als Dr Walter Jennings |
 | Julian Curry als Dr. Vargas |
| Peter Law als Dr. Kessler |
 | Jon Rumney als German Scientist |
 | Khan Bonfils als Creepy |
| Samta Gyatso als Scary |
 | Louis Hilyer als Executive Officer |
| Mark Wells als Communication Engineer |
| James Cash als Uniformed Officer |
| Tenzin Bhagen als Kalacakra Priest |
| Thupten Tsondru als Dying Old Man |
| Matthew Grant als Crewman #1 |
 | Steve Morphew als Crewman #2 |
 | Nancy Crane als Receptionist |
 | Stuart Milligan als Police Sergeant |
| Paul Canter als Police Officer |
 | Demetri Goritsas als Radio Operator |
 | William Hope als American Broadcaster |
 | Jonathan Keeble als British Broadcaster |
 | Stephane Cornicard als French Broadcaster |
 | Stephen Ballantyne als German Broadcaster |
| Victor Sobchak als Russian Broadcaster |
 | Mido Hamada als Soldier |
 | Gerard Monaco als Technician |
| Chris Robson als Hindenburg Porter |
| Matthew Coulter als Hindenburg Boy |
| Merritt Yohnka als Construction Worker |
| Charlotte Kyle als Hindenberg Passenger (uncredited) |
 | James Bannon als Voice Actor (uncredited) |
| Karl Champley als Pilot (uncredited) |
| David Decio als Pilot (uncredited) |
| Matthew Feitshans als Officer (uncredited) |
 | Sky Soleil als Officer (uncredited) |
| Chuen Tsou als Buddhist Monk (uncredited) |
| Jude Law | Producer |
| Jon Avnet | Producer |
| Raffaella De Laurentiis | Executive Producer |
| Kevin Conran | Production Design |
| Sadie Frost | Producer |
| Bill Haber | Executive Producer |
| Kevin Conran | Costume Design |
| Sabrina Plisco | Editor |
| Marsha Oglesby | Producer |
| Kerry Conran | Writer |
| Kerry Conran | Director |
| Sheila Trezise | Casting |
| Ed Shearmur | Original Music Composer |
| Eric Adkins | Director of Photography |
| Kirsten Conran | Art Direction |
| Aurelio De Laurentiis | Executive Producer |
| Hester Hargett | Co-Producer |
| Brooke Breton | Co-Producer |
| Stella McCartney | Costume Design |
| Miae Kim | Color Designer |
| Colin Sittig | Compositors |
| Justin Hammond | Lighting Technician |
| Rachel Wyn Dunn | Compositors |
| Brett Paton | Animation |
| John Dillon | Compositors |
| Merrick Rustia | Animation |
| Robert Gordon | Associate Producer |
| Tom Barrett | Visual Effects Editor |
| Tom Chichester-Clark | Additional Music |
| Jeff Goldman | Digital Effects Supervisor |
| Gary Pollard | Makeup Effects |
| Mark Henson | Stunt Coordinator |
| Judy Bradbury | Set Designer |
| Dylan Jones | Loader |
| Richard O. Helmer | Special Effects Coordinator |
| Jason Beale | Post Production Assistant |
| Clark Henderson | Post Production Supervisor |
| Tony Rush | Video Assist Operator |
| Marcia Gay | Assistant Director |
| Jonathan Downing | Standby Painter |
| James Rothrock | Software Engineer |
| Paul Sadeghi | Editorial Coordinator |
| Mark Barrs | First Assistant Camera |
| Keith Hamshere | Still Photographer |
| Eloisa De Laurentiis | Makeup Artist |
| Devin Bunje | Systems Administrators & Support |
| Tony Rowland | Grip |
| Carrie Wilksen | Art Department Coordinator |
| Sophia M. Crawford | Utility Stunts |
| Darren Thackeray | Driver |
| Thom Schillinger | Conceptual Design |
| Pie Lombardi | Assistant Costume Designer |
| David Wainstain | Sequence Supervisor |
| Colette Appleby | Stand In |
| Steven Hall | Camera Operator |
| Kay Georgiou | Key Hair Stylist |
| Shadi Almassizadeh | CG Supervisor |
| Elton Farla | Set Medic |
| Betty Glasow | Hairstylist |
| Sally Jones | Script Supervisor |
| Marcia Gay | Production Manager |
| Todd Toon | Supervising Sound Editor |
| Anthony Fung | Lighting Artist |
| Todd Toon | Sound Designer |
| Trevor Wood | Special Effects Supervisor |
| Aaron Sims | Visual Effects Art Director |
| Janet Farris | Casting Associate |
| Adam Kopald | Sound Effects Editor |
| Christopher Almerico | Visual Effects Coordinator |
| John Casali | Boom Operator |
| Brandon Evans | Rigging Gaffer |
| Mark A. Tracy | First Assistant Sound Editor |
| Marc Sadeghi | Executive Visual Effects Producer |
| Alec Bartsch | Supervising Technical Director |
| Valance Eisleben | Editorial Services |
| Sean Haeseler | Gaffer |
| Omar McClinton | Production Coordinator |
| Robert Elhai | Orchestrator |
| Margaux Mackay | Supervising Producer |
| Erik Jessen | First Assistant Editor |
| Steven Swanson | Lighting Supervisor |
| Christopher Hobbs | Visual Effects |
| David Crozier | Sound Mixer |
| Mauricio Baiocchi | Animation Supervisor |
| Lindsay Adams | Digital Compositors |
| Simon Eves | Researcher |
| Bonnie Lemon | Digital Producer |
| Matthew Feitshans | Production Supervisor |
| Michael K. Bauer | Music Editor |
| Melissa Almeida | 3D Supervisor |
| Melissa Brockman | Visual Effects Producer |
| Tim Alexander | Visual Effects Supervisor |
| Brian Miller | I/O Supervisor |
| Laurence Harvey | Armorer |
| David E. Harshbarger | Property Master |
| Terry Porter | Sound Re-Recording Mixer |
| Gary Summers | Additional Sound Re-Recording Mixer |
| Devon Heffley Curry | ADR Supervisor |
| John Kwiatkowski | Dialogue Editor |
| Christopher Boyes | Additional Sound Re-Recording Mixer |
| Lyoung Hui Kim | CG Artist |
| Randy Singer | Foley Mixer |
| Robin Harlan | Foley Artist |
| Chris Burgess | Third Assistant Director |
| Eric Aupetit | Dolly Grip |
| John Velazquez | Senior Animator |
| Donnie Creighton | Digital Intermediate Assistant |
| Bill Murphy | Visual Effects Production Manager |
| Steven Kirkby | Wardrobe Master |
| Anne Brault | Wardrobe Supervisor |
| Christopher Brennan | Special Effects Technician |
| Kate Reid | Camera Trainee |
| Steve Bowen | Digital Color Timer |
| H Haden Hammond | Lead Animator |
| Simon Drew | Casting Assistant |
| Steven J. Scott | Digital Intermediate Colorist |
| Valerie Davidson | Foley Supervisor |
| Sarah Ogletree | Post Production Coordinator |
| Andy Hopkins | Best Boy Grip |
| Jarik Van Sluijs | Creative Director |
| James Dornoff | Visual Effects Production Assistant |
| Tim Coulter | Associate Editor |
| Nicola 'Nikki' Berwick | Stunt Double |
| Richard Pagano | Casting Consultant |
| Rebecca Gore | Wardrobe Assistant |
| Georgina Napier | Costume Assistant |
| Doc Kane | ADR Mixer |
| Michael Kennedy | Digital Intermediate Producer |
| Jenny Hawkins | Dresser |
| Chad Danieley | Title Designer |
| Scott E. Anderson | Senior Visual Effects Supervisor |
| Radost Yonkova Ridlen | Visual Effects Compositor |
| Ben Howard | Second Assistant Director |
| Kevin O'Neill | 2D Supervisor |
| John M. Barbour | Assistant Camera |
| Dana B. Wilson | Assistant Editor |
| Amy Pawlowski | Digital Intermediate Editor |
| Susan A. Campbell | Digital Imaging Technician |
| Jesse D'Angelo | Storyboard Artist |
| Alexander Beddow | ADR Recordist |
| Craig Campobasso | Additional Casting |
| Ben Estrada | Digital Colorist |
| Carole Cowley | Head of Production |
| Richard Gervan | Rotoscoping Artist |
| Jennifer Alessi | Extras Casting |
| Tim Dobbert | Matchmove Supervisor |
| Caroline Richards | Assistant Production Coordinator |
| Jacqueline Rosado | Coordinating Producer |
| Matthias Gohl | Music Producer |
| Jon Avnet | Presenter |
| Michael Taylor | Production Executive |
| Greg Manke | Intern |
| Dylan Cole | Matte Painter |
| Olivier Beaulieu | Production Assistant |
| Catherine Charlton | Dialogue Coach |
| Jance Allen | Compositing Supervisor |
| Tim Coulter | Visual Effects Editor |
| James Mann | Rigging Grip |
