 | John Boyega als Fontaine |
 | Jamie Foxx als Slick Charles |
 | Teyonah Parris als Yo-Yo |
 | Kiefer Sutherland als Nixon |
 | David Alan Grier als The Preacher |
 | J. Alphonse Nicholson als Isaac |
 | Tamberla Perry als Biddy |
 | Eric Robinson Jr. als Big Moss |
 | Trayce Malachi als JuneBug |
 | Shariff Earp als Crutches |
 | Leon Lamar als Frog |
 | Joshua Mikel als DJ Strangelove |
 | Ryan Dinning als Cleanroom Suit Guy |
 | Swift Rice als The Deacon |
 | Megan Sousa als Ree-Ree |
 | Charity Jordan als Split Ends |
 | Austin Freeman als Bespectacled Tech |
 | David Shae als Chicken Manager |
 | Jessica Fontaine als Another Prostitute |
 | Patrick Fleming als Bored Tech #1 |
 | Nick Arapoglou als Bored Tech #2 |
 | Shinar Frazier als The John |
 | Jason Burkey als Oversight Tech |
| Randy Waters als Buddy with the Phone |
 | Al-Teron als Tank Top |
| Kia Shine als Dreads |
| Lou Young als Swole Muhfucka |
 | Juel Taylor als The Homie |
| Garin Flowers als CNN Reporter |
| Ms. Boo als Middle Aged Lady |
| Danny Zartman als Goop Tech #1 |
 | Adam Cronan als Goop Tech #2 |
| Dajanae Cole als Clone Ma'am |
 | Elliott Dixon als Clone Sir |
| Alvin Ashby als Person 1 (Comm) |
| Raianna Brown als Person 2 (Comm) |
| Justin J. Jordan als Clerk (Comm.) |
 | Marc Inniss als Devin (20s) (Comm.) |
| Jalen Jordan als Pod Kid |
| Osahon Tongo als The Mighty O (or, the screaming man in the cell) |
| Urquida Davis als Ol' Girl |
 | Michael A. Dean als The Cashier |
| Jatona King als Angry Girlfriend |
| Bricine Brown als Angry Boyfriend |
 | Suzanne C. Robertson als The First Reporter |
 | Tangela Large als The Second Reporter |
 | Mark Pettit als The Third Reporter |
| Prescott Morgan als The Carjackee |
| Darrell Stewart als Swole Muhfucka #2 |
 | Big Boy als Big Boy (voice) |
 | Jason Louder als Gold Grill (uncredited) |
 | Robert Tinsley als Scientist (uncredited) |
| Juel Taylor | Director |
| Jamie Foxx | Producer |
| Charles D. King | Producer |
| Stephen "Dr" Love | Producer |
| Jack L. Murray | Executive Producer |
| Juel Taylor | Producer |
| Datari Turner | Producer |
| Mark R. Wright | Executive Producer |
| Tony Rettenmaier | Producer |
| Ken Seng | Director of Photography |
| Saira Haider | Editor |
| Franco-Giacomo Carbone | Production Design |
| Jesse Rosenthal | Supervising Art Director |
| Tangela Large | Dialect Coach |
| Kim Taylor-Coleman | Casting |
| Monte Lipman | Executive Producer |
| Dana Sano | Executive Producer |
| Nathan Krochmal | Art Direction |
| Pierre Charles | Original Music Composer |
| Sarah Carter | Set Decoration |
| Kim Roth | Executive Producer |
| Poppy Hanks | Co-Executive Producer |
| James Lopez | Co-Executive Producer |
| Juel Taylor | Writer |
| Tony Rettenmaier | Writer |
| Jeremy Dell | Makeup Department Head |
| J. Denelle | Makeup Artist |
| Shawn Janifer | Makeup Artist |
| Tracey Moss | Key Hair Stylist |
| Ralph A. Ochoa | Hair Department Head |
| Danielle Peebles | Makeup Artist |
| Jovanti Robinson | Makeup Artist |
| Tomica Sarver | Hairstylist |
| Demario Ward | Makeup Artist |
| Brian Avery | Second Unit Director |
| Kaylee Johnson | Second Assistant Director |
| Osahon Tongo | Second Unit Director |
| Marvin Williams | First Assistant Director |
| Mayumi Konishi-Valentine | Set Designer |
| Sedrick Lakpa | Set Dresser |
| Lyndsey Monconduit | Set Decoration Buyer |
| Alexander K. Riba | Set Dresser |
| Ryan Sbaratta | Set Designer |
| Michael H. Ward | Set Designer |
| Brandon Bak | Foley Artist |
| Jan Bezouška | Sound Effects Editor |
| Greg Crawford | ADR Mixer |
| Aaron Diecker | ADR Editor |
| Dusty Fields | Utility Sound |
| Trevor Gates | Supervising Sound Editor |
| Judah Getz | ADR Mixer |
| Zack Goldsborough | Sound Recordist |
| Craig Mann | Supervising Sound Editor |
| Craig Mann | Sound Re-Recording Mixer |
| Sean Miller | ADR Recordist |
| Chris Navarro | ADR Mixer |
| Matthew Nicolay | Sound Mixer |
| Jeffrey Roy | ADR Mixer |
| Russell Topal | Sound Effects Editor |
| Laura Wiest | Sound Re-Recording Mixer |
| Ryan Maharaj | Casting Associate |
| Ian Clampett | Camera Operator |
| Devin Doyle | Camera Operator |
| Danny Durr | Gaffer |
| Ashton A Miller | Grip |
| Brendan Urckfitz | Grip |
| Sundari Moneek Reid | Costume Supervisor |
| Brian Avery | Stunt Coordinator |
| Tennison Barry | Stunt Double |
| Sadiqua Bynum | Stunt Double |
| Dave Cutler | Stunt Driver |
| Niko Dalman | Stunts |
| Thomas DuPont | Stunts |
| Kevin Dyer | Stunts |
| Jermaine Edmondson | Stunt Double |
| Simeon Freeman | Stunts |
| Jason Elwood Hanna | Stunt Driver |
| Jermaine Holt | Stunt Driver |
| Crystal Hooks | Stunt Double |
| Bobby James | Stunts |
| Floyd Anthony Johns Jr. | Stunts |
| Karin Justman | Stunts |
| Michelle Ladd | Stunt Driver |
| Steven Legate | Stunts |
| T. Ryan Mooney | Stunts |
| David Andrew Nash | Stunt Driver |
| Taraja Ramsess | Stunt Driver |
| Stephon Rodgers | Stunt Double |
| Dena Sodano | Stunts |
| Todd Rogers Terry | Stunt Double |
| Jeremy Chapman Webb | Stunt Double |
| Al Thompson | Stunts |
| Joshua Wade | Stunts |
| Donte Walker | Stunts |
| Mark R. Byers | Special Effects Supervisor |
| Samantha Goodelle | Special Effects |
| Shannon Pitts | Special Effects |
| Garrett V. Martin | Special Effects Technician |
| Wes Mattox | Special Effects Technician |
| Ian McCall | Special Effects Technician |
| Abdullah Azizi | Visual Effects Coordinator |
| Tierra Harris | Visual Effects Coordinator |
| Mark LeDoux | Visual Effects Supervisor |
| Sean Lyndon Martin | VFX Artist |
| Bobby Tucker | Visual Effects Producer |
| Joshwa Walton | VFX Artist |
| Jennifer Badger | Stunt Driver |
| Justin J. Jordan | Graphic Designer |
| Suzanne C. Robertson | Visual Effects Coordinator |
