 | Meg Ryan als Kate McKay |
 | Hugh Jackman als Leopold 'Leo' Mountbatten, Duke of Albany |
 | Liev Schreiber als Stuart Besser |
 | Breckin Meyer als Charlie McKay |
 | Natasha Lyonne als Darci |
 | Bradley Whitford als J.J. Camden |
 | Paxton Whitehead als Uncle Millard |
 | Spalding Gray als Dr. Geisler |
 | Josh Stamberg als Colleague Bob |
 | Matthew Sussman als Ad Executive Phil |
 | Philip Bosco als Otis |
 | Stephanie Sanditz als Gretchen |
 | Charlotte Ayanna als Patrice |
 | Andrew Jack als Roebling |
| Stan Tracy als Photographer |
 | Kristen Schaal als Miss Tree |
| William Sanford als Barry |
 | Arthur J. Nascarella als Gracy |
 | Robert Ray Manning Jr. als Passerby |
| Roma Torre als TV Newscaster |
 | Viola Davis als Policewoman |
| Ray Seiden als Sanitation Worker |
 | Jonathan Fried als Faux Wolfgang |
 | Francis Dumaurier als Faux Emeril |
 | Cole Hawkins als Hector |
| Stephanie Montalvo als CRG Intern |
 | Ebony Jo-Ann als Nurse Ester |
 | George Hahn als Assistant Director |
| Joseph Mosso als Cameraman |
| Cornelius Byrne als Carriage Driver |
 | Chazz Menendez als Purse Thief |
| Brandon Parrish als Dennis |
 | Ginger Britt Daniels als Monica |
 | Martha Madison als Office Woman |
| Nai Yuan Hu als Rooftop Violinist |
| Michael Shelle als Distinguished Actor |
| Matthew Beisner als Commercial Director |
| Bill Corsair als Limo Driver |
 | John Rothman als Executive #1 |
| Dennis Rees als Executive #2 |
| Michael Cassady als Executive #3 |
 | Brian Letscher als Ad Executive |
 | Meg Gibson als Executive's Wife |
 | Kevin Daniels als Doorman at Party |
| Henry Boyle als Cab Driver |
| Russell Di Perna als Bridge Cop |
| Frank Arcuri als 1876 Doorman |
| Andrea Barnes als Clara (uncredited) |
 | Del Pentecost als Marty (uncredited) |
 | Domenick Lombardozzi als Counterman (Uncredited) |
 | Craig Bierko als Actor in Advertisement (uncredited) |
 | James Mangold als Irate Director Richard (uncredited) |
 | David Aaron Baker als 2nd Studio Executive (uncredited) |
 | Shalom Harlow als Woman in Movie (uncredited) |
| Eddie Marrero als Hospital Orderly (uncredited) |
| Todd Poudrier als Bartender (uncredited) |
| Colby Ryan als Flower Shop Clerk (uncredited) |
| Jorjeana Marie als Leopold's Maid (uncredited) |
 | Diana Brownstone als Prospective Fiancée (uncredited) |
 | Peggy Flood als Prospective Fiancée (uncredited) |
| James Mangold | Director |
| Steven Rogers | Screenplay |
| Cathy Konrad | Producer |
| Rolfe Kent | Original Music Composer |
| Stuart Dryburgh | Director of Photography |
| David Brenner | Editor |
| James Mangold | Screenplay |
| Stephanie Carroll | Set Decoration |
| Sheila Waldron | Script Supervisor |
| Mark Friedberg | Production Design |
| Amy Andrews | Costume Supervisor |
| Laura Steinman | Set Costumer |
| Steven Rogers | Story |
| Kerry Barden | Casting |
| Carla White | Makeup Department Head |
| Jess Gonchor | Art Direction |
| Frankie Ritacco | Costume Supervisor |
| Claire Kirk | Art Department Coordinator |
| Suzanne Smith Crowley | Casting |
| Karen Kawahara | Makeup Artist |
| Billy Hopkins | Casting |
| Bob Weinstein | Executive Producer |
| Harvey Weinstein | Executive Producer |
| Christopher Goode | Co-Producer |
| Kerry Orent | Executive Producer |
| Meryl Poster | Executive Producer |
| Peter Bucossi | Stunt Coordinator |
| Paul Bucossi | Stunts |
| Christopher Goode | Unit Production Manager |
| Nicholas Mastandrea | First Assistant Director |
| Amy Lauritsen | Second Assistant Director |
| Jennifer Truelove | Second Second Assistant Director |
| Miguel López-Castillo | Assistant Art Director |
| Stephen Consentino | "B" Camera Operator |
| Stephen Consentino | Steadicam Operator |
| John Baer | Still Photographer |
| Mathew Price | Production Sound Mixer |
| Dan Guachione | Boom Operator |
| Timothy Metzger | Leadman |
| Peggy Schierholz | Hairstylist |
| John Quaglia | Key Hair Stylist |
| Hilary Niederer | Wardrobe Assistant |
| Michael McCusker | First Assistant Editor |
| Howell Gibbens | Supervising Sound Editor |
| Elizabeth Kenton | Dialogue Editor |
| Larry Kemp | Dialogue Editor |
| Mike Chock | Dialogue Editor |
| Mary Andrews | Supervising ADR Editor |
| James Morioka | Assistant Sound Editor |
| David Boulton | ADR Mixer |
| Robert Deschaine | ADR Mixer |
| Peter Gleaves | ADR Mixer |
| Howard London | ADR Mixer |
| David Weisberg | ADR Mixer |
| Vincent Guisetti | Foley Artist |
| Pamela Kahn | Foley Artist |
| Kyle Rochlin | Foley Mixer |
| James Wright | Dolby Consultant |
| Jeffrey J. Haboush | Sound Re-Recording Mixer |
| Bill W. Benton | Sound Re-Recording Mixer |
| Nick South | Music Editor |
| Paul Rabjohns | Music Editor |
| Tony Blondal | Orchestrator |
| William T. Stromberg | Conductor |
| Michael Farrow | Scoring Mixer |
| Robert Stromberg | Visual Effects Supervisor |
| Julia Frey | Visual Effects Producer |
| Robert Scifo | Matte Painter |
| Patrick Zentis | Matte Painter |
| Diana Burton | Property Master |
| Keri Lederman | Assistant Property Master |
| Connie Brink | Special Effects Coordinator |
| Ralph Volpe | Transportation Captain |
| Gene Engels | Gaffer |
| Steve Comesky | Best Boy Electric |
| Francis J. McBride | Rigging Gaffer |
| Dennis Gamiello | Key Grip |
| Edward W. Lowry | Dolly Grip |
| Carla Raij | Location Manager |
| Jessica Archer | Location Coordinator |
| Mark Paul Selemon | Greensman |
| Thomas Costabile | Construction Coordinator |
| Michael Herlihy | Construction Foreman |
| Patricia Porter | Payroll Accountant |
| Molly Clayton | Casting Assistant |
| Barbara Harris | ADR Voice Casting |
| Cara Leibovitz | Unit Publicist |
| Matvey Shatz | Color Timer |
| Audrey Wells | Additional Writing |
| Danny Aiello III | Stunts |
| Jerry Cetrulo | Stunts |
| Stracy Diaz | Stunts |
| Don Hewitt Jr. | Stunts |
| Vic Bucossi | Stunts |
| Michael Russo | Stunts |
| John Copeman | Stunts |
| Ken Harris | Stunts |
| Donal Oldaker | Stunt Double |
| Amy Yanagisawa | Stunts |
| Victor Chan | Stunts |
| Roy Farfel | Stunts |
| Jery Hewitt | Stunts |
| David Shumbris | Stunts |
| Jay Carrado | Stunts |
| Pete Corby | Stunts |
| Don Hewitt Sr. | Stunts |
| Jodi Michelle Pynn | Stunts |
| Donna Zakowska | Costume Designer |
