 | William Shatner als Admiral James T. Kirk |
 | Leonard Nimoy als Mr. Spock |
 | DeForest Kelley als Dr. Leonard 'Bones' McCoy |
 | James Doohan als Cmdr. Montgomery 'Scotty' Scott |
 | George Takei als Lt. Cmdr. Hikaru Sulu |
 | Walter Koenig als Lt. Pavel Chekov |
 | Nichelle Nichols als Lt. Cmdr. Uhura |
 | Stephen Collins als Captain William Decker |
 | Persis Khambatta als Lt. Ilia / The Probe |
 | Majel Barrett als Dr. Christine Chapel |
 | Grace Lee Whitney als CPO Janice Rand |
 | Mark Lenard als Klingon Captain |
 | Billy Van Zandt als Alien Boy |
 | Roger Aaron Brown als Epsilon Technician |
 | Gary Faga als Airlock Technician |
 | Franklyn Seales als Crew Member |
 | Joel Kramer als Klingon Crewman |
 | David Gautreaux als Cmdr. Branch |
 | John Gowans als Assistant to Rand |
| Howard Itzkowitz als Cargo Deck Ensign |
| Jon Rashad Kamal als Lt. Cmdr. Sonak |
 | Marcy Lafferty als Chief DiFalco |
| Michele Povill als Lieutenant |
| Jeri McBride als Technician |
| Terrence O'Connor als Chief Ross |
| Michael Rougas als Lt. Cleary |
| Susan O'Sullivan als Woman |
| Ralph Brannen als Crew Member |
| Ralph Byers als Crew Member |
| Paula Crist als Crew Member |
| Iva Lane als Crew Member |
| Momo Yashima als Crew Member |
| Jimmie Booth als Klingon Crewman |
| Dave Moordigian als Klingon Crewman |
 | Tom Morga als Klingon Crewman |
| Tony Rocco als Klingon Crewman |
| Joel Schultz als Klingon Crewman |
| Craig Thomas als Klingon Crewman |
| Edna Glover als Vulcan Master |
| Norman Stuart als Vulcan Master |
| Paul Weber als Vulcan Master |
| Joshua Gallegos als Security Officer |
| Lisa Chess als Yeoman |
| Leslie C. Howard als Yeoman |
| Sayra Hummel als Technical Assistant |
| Junero Jennings als Technical Assistant |
 | Christopher Doohan als Extra (uncredited) |
| Richard H. Kline | Director of Photography |
| Harold Michelson | Production Design |
| Linda DeScenna | Set Decoration |
| Robert Wise | Director |
| John Vallone | Art Direction |
| Robert Fletcher | Costume Design |
| Gene Roddenberry | Producer |
| Marvin Paige | Casting |
| Todd C. Ramsay | Editor |
| Alexander Courage | Original Music Composer |
| Jon Povill | Producer |
| Leon Harris | Art Direction |
| Joseph R. Jennings | Art Direction |
| Jerry Goldsmith | Original Music Composer |
| Ve Neill | Makeup Artist |
| Harold Livingston | Screenplay |
| Alan Dean Foster | Story |
| Douglas Trumbull | Visual Effects |
| Robert Elswit | Visual Effects Camera |
| Janna Phillips | Makeup Artist |
| Fred B. Phillips | Makeup Artist |
| Carlos Yeaggy | Makeup Artist |
| Rick Stratton | Makeup Effects |
| Phil Rawlins | Unit Production Manager |
| Lindsley Parsons Jr. | Executive In Charge Of Production |
| Douglas E. Wise | Second Assistant Director |
| Daniel McCauley | Assistant Director |
| Noyan Cosarer | Sound Re-Recording Mixer |
| Richard L. Anderson | Supervising Sound Editor |
| Steve Maslow | Sound Re-Recording Mixer |
| Gregg Landaker | Sound Re-Recording Mixer |
| Bill Varney | Sound Re-Recording Mixer |
| Keith Lane Jensen | Stunts |
| Bob Bralver | Stunts |
| Bill Couch | Stunts |
| John Hugh McKnight | Stunts |
| Kym Washington Longino | Stunts |
| Tom Morga | Stunt Double |
| Larry D. Howard | Gaffer |
| Bonnie Prendergast | Script Supervisor |
| John Dykstra | Visual Effects |
| Richard Yuricich | Visual Effects |
| Robert Swarthe | Animation Supervisor |
| Tom Overton | Sound Mixer |
| Stephen Hunter Flick | Sound Editor |
| Cecelia Hall | Sound Editor |
| Alan Robert Murray | Sound Editor |
| Colin Waddy | Sound Editor |
| George Watters II | Sound Editor |
| Dirk Dalton | Sound Effects |
| Joel Goldsmith | Sound Effects |
| Alan Howarth | Sound Effects |
| Francesco Lupica | Sound Effects |
| Frank Serafine | Sound Effects |
| Alex Weldon | Special Effects Coordinator |
| Darrell Pritchett | Special Effects Coordinator |
| Ray Mattey | Special Effects Coordinator |
| Martin Bresin | Special Effects Coordinator |
| Matthew Yuricich | Matte Painter |
| Rocco Gioffre | Matte Painter |
| Harry Moreau | Animation |
| Richard Foy | Title Designer |
| Robert Abel | Visual Effects |
