 | Ewan McGregor als Ed Bloom (young) |
 | Albert Finney als Ed Bloom (senior) |
 | Billy Crudup als Will Bloom |
 | Jessica Lange als Sandra Bloom (senior) |
 | Helena Bonham Carter als Jenny (young & senior) / The Witch |
 | Alison Lohman als Sandra Bloom (young) |
 | Robert Guillaume als Dr. Bennett (senior) |
 | Marion Cotillard als Josephine |
 | Matthew McGrory als Karl the Giant |
 | David Denman als Don Price (age 18-22) |
 | Missi Pyle als Mildred |
 | Loudon Wainwright III als Beamen |
 | Ada Tai als Ping |
 | Arlene Tai als Jing |
 | Steve Buscemi als Norther Winslow |
 | Danny DeVito als Amos Calloway |
 | Deep Roy als Mr. Soggybottom |
 | Perry Walston als Ed Bloom (age 10) |
 | Hailey Anne Nelson als Jenny (age 8) |
| Grayson Stone als Will Bloom (age 6-8) |
 | R. Keith Harris als Ed's Father |
 | Karla Droege als Ed's Mother |
| Zac Gardner als Zacky Price (age 10) |
 | John Lowell als Don Price (age 12) |
 | Darrell Vanterpool als Wilbur (age 10) |
 | Miley Cyrus als Ruthie (age 8) |
| Joseph Humphrey als Little Brave |
 | Morgan Grace Jarrett als Will's Date |
| Sallie Hedrick als Pretty Girl |
| Charles McLawhorn als Mayor |
 | Frank Hoyt Taylor als Sharecropper |
| Savanna James als Little Girl |
 | Billy Redden als Banjo man |
 | James DeForest Parker als Shotgun Toter |
 | Russell Hodgkinson als Some Farmer |
| Don Young als Shephard |
| Jayne Morgan als Townsperson |
| David Ramsey als Townsperson |
| Greg Hohn als Townsperson |
 | Zach Hanner als Cashier |
| George McArthur als Colossus |
| Jeff Campbell als Jump Leader |
 | Lawrence Sykkmon als Chinese Emcee |
 | Bonnie Johnson als Teller Woman |
| Howard Houston Jr. als Piano Student |
| Joanne Pankow als Heavy Set Nurse |
 | Trevor Gagnon als Will's son |
| Jacob Radford als Kid |
| Karlos Walkes als Dr. Bennett (young) |
| Cathy Berry als Lobster Woman |
| John Fugate als Side Show Barker |
| Daniel Wallace als Econ Professor |
| Metz Duites als Ventriloquist |
| Vincent J. Ybiernas als Asian Officer |
| Barry C. Harvard als Chicken Plant Operator |
| Edward Aldag als Municipal Dump Owner |
| Michael Garnet Stewart als Auctioneer |
| C. Alan Rawlins Sr. als Pretty Man |
| Jake Brake als Old Zacky |
 | Bevin Kaye als River Woman |
 | L.C. Holt als Spectre Citizen (uncredited) |
| Will Thomas als Spectre Citizen (uncredited) |
| Richard D. Zanuck | Producer |
| Colleen Atwood | Costume Design |
| Roy Barnes | Art Direction |
| Richard L. Johnson | Art Direction |
| Dan Jinks | Producer |
| Jean-Michel Ducourty | Art Direction |
| Arne Schmidt | Executive Producer |
| Denise Chamian | Casting |
| Philippe Rousselot | Director of Photography |
| Bruce Cohen | Producer |
| Danny Elfman | Original Music Composer |
| Chris Lebenzon | Editor |
| Nancy Haigh | Set Decoration |
| John August | Screenplay |
| Tim Burton | Director |
| Jack Johnson | Art Direction |
| Robert Fechtman | Art Direction |
| Philippe Gallichet | Chef |
| Debra James | Unit Production Manager |
| Matthew Harrison | Foley Editor |
| Donna O'Neal | Key Set Costumer |
| Greg P. Russell | Sound mixer |
| Bob Badami | Music Supervisor |
| Dennis J. Lootens | Rigging Gaffer |
| Zade Rosenthal | Still Photographer |
| Guy Ferrandis | Still Photographer |
| Janna Stern | Script Supervisor |
| Mary Ellen Mark | Still Photographer |
| Jack English | Gaffer |
| Dorothy J. Pearl | Makeup Artist |
| Sherri Bramlett | Hairstylist |
| James M. Davis | Construction Foreman |
| Dawn Brown | Set Designer |
| Alice Powell | Seamstress |
| Petur Hliddal | Production Sound Mixer |
| David Guilbeau | Craft Service |
| Meyerer Miller | Production Office Assistant |
| Pedro Barquin | Stunts |
| Michel Aller | First Assistant Editor |
| Dennis S. Sands | Scoring Mixer |
| Ted Caplan | Sound Effects Editor |
| Domi Piturro | 3D Supervisor |
| Jeff Passanante | Construction Coordinator |
| Val Drake | Sculptor |
| Bill Diaz | Supervising Animator |
| Robin Citrin | Location Manager |
| Dennis Gassner | Production Design |
| Robert Ruiz | First Assistant Camera |
| Ellen Segal | Music Editor |
| Rohan Claassen | Visual Effects |
| Neal Norton | Steadicam Operator |
| Linda De Andrea | Hair Department Head |
| Jean Ann Black | Makeup Department Head |
| Cynthia Onrubia | Choreographer |
| Skip Lievsay | Supervising Sound Editor |
| Christina Ann Wilson | Assistant Art Director |
| Ben Shepherd | CGI Supervisor |
| Jos'h Hancher | Loader |
| John B. Clarey III | Propmaker |
| Michael J. Flynn | Greensman |
| David Norris | Camera Operator |
| Carla Meyer | Dialect Coach |
| Charles Croughwell | Stunt Coordinator |
| Steve Bowen | Color Timer |
| Chris Cummings | Art Department Coordinator |
| Scott Troha | Leadman |
| John Radcliff | Utility Stunts |
| Carl Fischer | Boom Operator |
| John E. Sasaki | Digital Compositors |
| Sara Philpott | Set Dressing Supervisor |
| Paddy Eason | Digital Effects Supervisor |
| Evan Schiff | Systems Administrators & Support |
| Lucy Ainsworth-Taylor | Visual Effects Producer |
| Michelle Skoby | Assistant Costume Designer |
| May Porter | Stand In |
| Dena Berman | Casting Associate |
| Geraldine Niche | Production Coordinator |
| Chamonix Bosch | Set Production Assistant |
| Christine Bodelot | Production Accountant |
| Jeff Atmajian | Orchestrator |
| Susan Antonelli | Set Costumer |
| Julie Saegert | Post Production Assistant |
| Steve Rhee | Visual Effects Editor |
| Kevin Scott Mack | Visual Effects Supervisor |
| John Eric Seay | Prop Maker |
| Timothy Michael Cairns | Quality Control Supervisor |
| Cha Blevins | Costume Supervisor |
| Tommy Harper | Second Unit |
| Bryan Booth | Electrician |
| Stephen Eno | Painter |
| Steve Humphrey | Picture Car Coordinator |
| Tina Canny | Projection |
| Michael Antunez | Transportation Coordinator |
| Jacky Hardouin | Carpenter |
| Taylor Bennett | Scenic Artist |
| Eileen Peterson | Unit Publicist |
| J. Wayne Parker | Rigging Grip |
| Katterli Frauenfelder | Associate Producer |
| Keith Marbory | Special Effects Supervisor |
| Benjamin Edelberg | Leadman |
| Robert Dawson | Title Graphics |
| Larry Hopkins | Sound Mixer |
| Stan Parks | Special Effects |
| Denis Samoilov | Animation |
| Gabriel Solana | Makeup Effects |
| Gloria Belz | Makeup Artist |
| Melissa Lytle | Assistant Sound Editor |
| Mark Berrow | Musician |
| Katterli Frauenfelder | First Assistant Director |
| Mo Henry | Negative Cutter |
| Rémy Boudet | Title Designer |
| Felipe Sanchez | Costume Illustrator |
| Colin Drobnis | Visual Effects Technical Director |
| Jack Blanchard | Set Dresser |
| Kerin Ferallo | Assistant Production Coordinator |
| Teri E. Dorman | Supervising Dialogue Editor |
| Ingrid Jungermann | Casting Assistant |
| Aaron Sims | Character Designer |
| Lee Clayton | Tailor |
| Rick Chavez | Assistant Property Master |
| Kevin Flatow | Assistant Production Manager |
| Vanessa Mujica | Third Assistant Director |
| C. Alan Rawlins Sr. | Key Grip |
| Craig Berkey | Sound Effects Designer |
| Kimberly Harris | Supervising ADR Editor |
| Darryl Humber | Dolly Grip |
| Susan Dawes | Dialogue Editor |
| Jerry Moss | Property Master |
| Daniel Wallace | Novel |
| Paul McGhee | Digital Color Timer |
| Curtis Lindersmith | Digital Intermediate Editor |
| Janella Bersabal | Extras Casting Assistant |
| Carlos De La Torre | Second Second Assistant Director |
| Dawn Blacksten | Assistant Location Manager |
| James Babineaux | Assistant Chief Lighting Technician |
| Stéphanie Champault | Second Assistant Director |
| Murray Barber | Digital Compositor |
| Michael Elson | Head of Production |
| Ségolène Amice Lagny | Production Secretary |
| Riko Schatke | Best Boy Grip |
| Meredith Apel | Assistant Editor |
| Joseph P. Hurt | Assistant Makeup Artist |
| Ben Estrada | Digital Colorist |
| Jeff W. Curtis | Grip |
| Marianne Shiffrar | Payroll Accountant |
| Howard London | ADR Mixer |
| Rick Baca | First Assistant Accountant |
| Don Baer | Driver |
| Dianne Chadwick | Graphic Designer |
| Lindsay MacGowan | Effects Supervisor |
| Niamh Murphy | Textile Artist |
| Amy Arnold | Costumer |
| Chris Baker | Storyboard Artist |
| Michael Forte | Stunt Driver |
| Mary Small | Catering |
| Scott Berrie | Production Assistant |
| Dean Zanuck | Production Executive |
| Tony Vandenecker | Special Effects Technician |
| Xiomara Comrie | Assistant Camera |
| Gary A. Hecker | Foley Artist |
| Brian Ruberg | Foley Mixer |
| Louis Smith | Second Assistant Camera |
| J. Wayne Parker | Key Rigging Grip |
| Noelle Coughlan | Second Assistant Accountant |
| Chris Bogart | Set Painter |
| Jason Arrington | Key Production Assistant |
| Olivier Suffert | Production Driver |
| Sean Landeros | Sound Recordist |
| Maryellen Aviano | Extras Casting Coordinator |
| Michelle Martin | Visual Effects Coordinator |
| Bevin Kaye | Stunts |
| Al Goto | Stunts |
| Corey Michael Eubanks | Stunts |
